- ICH GCP
- 미국 임상 시험 레지스트리
- 임상시험 NCT07604948
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period
2026년 5월 21일 업데이트: Ziyue Ou, Guangzhou Sport University
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period: A Randomized Controlled Trial
This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period.
Thirty-four male collegiate basketball players were randomly assigned to either an IPC group or a placebo control group.
Bilateral lower limb IPC intervention (3 cycles, each consisting of 5-minute ischemia at 220 mmHg and 5-minute reperfusion, twice per week for 6 weeks) was administered before routine basketball training sessions.
Lower limb explosive power, as well as physiological, biochemical, and morphological indices, were assessed before and after the intervention.
연구 개요
상태
모병
상세 설명
Background: Lower limb explosive power is crucial for basketball performance, and effective recovery strategies are key to maintaining training quality.
Ischemic preconditioning (IPC) is a non-invasive, economical, and safe method that triggers endogenous protective mechanisms through brief ischemia-reperfusion cycles, showing potential in enhancing athletic performance and metabolic efficiency.
However, the effects of IPC on lower limb explosive power during post-match recovery in basketball players remain understudied.
Objective: To investigate the effects of a 6-week repeated remote ischemic preconditioning on lower limb explosive power, phosphagen energy system capacity, and physical recovery in male college basketball players.
Design: A randomized, parallel-group, placebo-controlled trial with concealed allocation.
Participants were randomly assigned to either the IPC experimental group (n=17) or the placebo control group (n=17).
Both groups participated in the same regular basketball sessions.
The experimental group received bilateral thigh IPC intervention (3×5 minutes, 220 mmHg) before each training session, while the control group received a placebo intervention (3×5 minutes, 20 mmHg).
The intervention was administered twice a week for 6 weeks (30 minutes per session).
Secondary endpoints: Urinary creatinine coefficient, 10-second maximal load test (blood lactate increment, peak power, mean power), hematological parameters (red blood cell count, hemoglobin, hematocrit, white blood cell count), serum testosterone, cortisol, testosterone/cortisol ratio, body composition (body weight, body fat percentage, BMI), and training load monitoring (heart rate, RPE, urine protein).
연구 유형
중재적
등록 (추정된)
34
단계
- 해당 없음
연락처 및 위치
이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.
연구 연락처
- 이름: Ziyue Ou, PHD
- 전화번호: +8615626121623
- 이메일: 105852022100090@stu.gzsport.edu.cn
연구 장소
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Guangdong
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Guangzhou, Guangdong, 중국, 510430
- 모병
- Guangzhou Sport University
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연락하다:
- Ziyue Ou, PHD
- 전화번호: 15626121623
- 이메일: 105852022100090@stu.gzsport.edu.cn
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참여기준
연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.
자격 기준
공부할 수 있는 나이
- 성인
건강한 자원 봉사자를 받아들입니다
예
설명
Inclusion Criteria:
- Male basketball students at Guangzhou Sport University.
- Regular participants in basketball training/practice.
- Healthy adults without cardiovascular, hepatic, renal, digestive, neurological, or metabolic diseases.
- Blood pressure within normal range.
- No history of lower extremity musculoskeletal injury within the past 6 months.
- Not currently using any performance-enhancing substances or medications affecting hormones/metabolism.
- Voluntary participation with signed informed consent.
Exclusion Criteria:
- Presence of acute or chronic diseases affecting exercise performance.
- History of deep vein thrombosis or coagulation disorders.
- Presence of skin lesions or infections at the thigh cuff placement site.
- Participation in other concurrent lower extremity strength/power training programs outside the study.
- Use of dietary supplements known to affect muscle metabolism within 4 weeks prior to enrollment.
- Inability to complete the full 6-week intervention and testing protocol.
공부 계획
이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 하나의
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: IPC Group
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475).
Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions.
The intervention was conducted twice per week for 6 weeks.
Cuff placement: at the inguinal crease of the thigh.
Subject position: supine, alternating between left and right legs.
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Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475).
Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions.
The intervention was conducted twice per week for 6 weeks.
Cuff placement: at the inguinal crease of the thigh.
Subject position: supine, alternating between left and right legs.
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활성 비교기: Sham Control Group
Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training.
Twice weekly for 6 weeks.
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Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training.
Twice weekly for 6 weeks.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Squat Jump (SJ) height
기간: Baseline (Week 0) and Post-intervention (Week 8)
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Change from baseline in lower extremity concentric explosive power measured by Smart Jump portable contact mat (cm).
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Baseline (Week 0) and Post-intervention (Week 8)
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Countermovement Jump (CMJ) height
기간: Baseline and Week 8
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Change from baseline in lower extremity reactive explosive power without arm swing (cm).
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Baseline and Week 8
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Standing Long Jump
기간: Baseline and Week 8
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Change from baseline in lower extremity horizontal explosive power (cm).
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Baseline and Week 8
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T-Test (T-run)
기간: Baseline and Week 8
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Change from baseline in multi-directional agility performance (seconds).
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Baseline and Week 8
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3/4 Court Sprint
기간: Baseline and Week 8
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Change from baseline in linear sprint speed over 3/4 basketball court distance (~21m, seconds).
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Baseline and Week 8
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Reactive Strength Index (RSI)
기간: Baseline and Week 8
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Change from baseline in RSI derived from 30cm drop jump using Smart Jump system (m/s).
The RSI was calculated as jump height divided by ground contact time, with higher values indicating better reactive strength capacity in athletes (i.e., shorter ground contact times and greater jump heights).
The observed range of RSI in the present study was [minimum value]-[maximum value] m/s.
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Baseline and Week 8
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
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Blood Lactate Accumulation
기간: Baseline and Week 8
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Change in blood lactate accumulation during 10-second maximal load test (mmol/L).
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Baseline and Week 8
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Peak Power (10s Test)
기간: Baseline and Week 8
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Change from baseline in peak power output during 10-second maximal load test on Monark 828E cycle ergometer (Watts).
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Baseline and Week 8
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Mean Power (10s Test)
기간: Baseline and Week 8
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Change from baseline in mean power output during 10-second maximal load test (Watts).
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Baseline and Week 8
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Testosterone/Cortisol Ratio
기간: Baseline and Week 8
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Change from baseline in T/C ratio (×10-²).
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Baseline and Week 8
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공동 작업자 및 조사자
여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.
간행물 및 유용한 링크
연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.
일반 간행물
- Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD, Redington AN. Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sports Exerc. 2011 Jul;43(7):1280-6. doi: 10.1249/MSS.0b013e318206845d.
- Bailey TG, Jones H, Gregson W, Atkinson G, Cable NT, Thijssen DH. Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sports Exerc. 2012 Nov;44(11):2084-9. doi: 10.1249/MSS.0b013e318262cb17.
- Cheng CF, Kuo YH, Hsu WC, Chen C, Pan CH. Local and Remote Ischemic Preconditioning Improves Sprint Interval Exercise Performance in Team Sport Athletes. Int J Environ Res Public Health. 2021 Oct 12;18(20):10653. doi: 10.3390/ijerph182010653.
- Chen Y, Yang J, Muradov O, Li X, Lee JKW, Qiu J. Effect of ischemic preconditioning on maximum accumulated oxygen deficit in 400-meter runners. Eur J Sport Sci. 2023 May;23(5):789-796. doi: 10.1080/17461391.2022.2064769. Epub 2022 Apr 25.
- Caru M, Levesque A, Lalonde F, Curnier D. An overview of ischemic preconditioning in exercise performance: A systematic review. J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23.
- Ou Z, Yang L, Zhu H, Weng X, Xu G. Ischemic preconditioning enhances autonomic nervous system modulation during frequency speed of kick test in taekwondo athletes: a randomized crossover study. BMC Sports Sci Med Rehabil. 2026 Feb 12;18(1):136. doi: 10.1186/s13102-026-01602-2.
- Carvalho L, Barroso R. Ischemic Preconditioning Improves Strength Endurance Performance. J Strength Cond Res. 2019 Dec;33(12):3332-3337. doi: 10.1519/JSC.0000000000002846.
연구 기록 날짜
이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.
연구 주요 날짜
연구 시작 (실제)
2026년 5월 22일
기본 완료 (추정된)
2026년 7월 15일
연구 완료 (추정된)
2026년 7월 15일
연구 등록 날짜
최초 제출
2026년 5월 17일
QC 기준을 충족하는 최초 제출
2026년 5월 17일
처음 게시됨 (실제)
2026년 5월 22일
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
2026년 5월 26일
QC 기준을 충족하는 마지막 업데이트 제출
2026년 5월 21일
마지막으로 확인됨
2026년 5월 1일
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- GZSU-IPC-BB-2024
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
미정
IPD 계획 설명
The data have not been publicly released yet, and contributions may be considered after they are published.
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
아니
미국 FDA 규제 기기 제품 연구
아니
이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .