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- Ensaio Clínico NCT07604948
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period
21 de maio de 2026 atualizado por: Ziyue Ou, Guangzhou Sport University
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period: A Randomized Controlled Trial
This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period.
Thirty-four male collegiate basketball players were randomly assigned to either an IPC group or a placebo control group.
Bilateral lower limb IPC intervention (3 cycles, each consisting of 5-minute ischemia at 220 mmHg and 5-minute reperfusion, twice per week for 6 weeks) was administered before routine basketball training sessions.
Lower limb explosive power, as well as physiological, biochemical, and morphological indices, were assessed before and after the intervention.
Visão geral do estudo
Status
Recrutamento
Condições
Intervenção / Tratamento
Descrição detalhada
Background: Lower limb explosive power is crucial for basketball performance, and effective recovery strategies are key to maintaining training quality.
Ischemic preconditioning (IPC) is a non-invasive, economical, and safe method that triggers endogenous protective mechanisms through brief ischemia-reperfusion cycles, showing potential in enhancing athletic performance and metabolic efficiency.
However, the effects of IPC on lower limb explosive power during post-match recovery in basketball players remain understudied.
Objective: To investigate the effects of a 6-week repeated remote ischemic preconditioning on lower limb explosive power, phosphagen energy system capacity, and physical recovery in male college basketball players.
Design: A randomized, parallel-group, placebo-controlled trial with concealed allocation.
Participants were randomly assigned to either the IPC experimental group (n=17) or the placebo control group (n=17).
Both groups participated in the same regular basketball sessions.
The experimental group received bilateral thigh IPC intervention (3×5 minutes, 220 mmHg) before each training session, while the control group received a placebo intervention (3×5 minutes, 20 mmHg).
The intervention was administered twice a week for 6 weeks (30 minutes per session).
Secondary endpoints: Urinary creatinine coefficient, 10-second maximal load test (blood lactate increment, peak power, mean power), hematological parameters (red blood cell count, hemoglobin, hematocrit, white blood cell count), serum testosterone, cortisol, testosterone/cortisol ratio, body composition (body weight, body fat percentage, BMI), and training load monitoring (heart rate, RPE, urine protein).
Tipo de estudo
Intervencional
Inscrição (Estimado)
34
Estágio
- Não aplicável
Contactos e Locais
Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.
Contato de estudo
- Nome: Ziyue Ou, PHD
- Número de telefone: +8615626121623
- E-mail: 105852022100090@stu.gzsport.edu.cn
Locais de estudo
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Guangdong
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Guangzhou, Guangdong, China, 510430
- Recrutamento
- Guangzhou Sport University
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Contato:
- Ziyue Ou, PHD
- Número de telefone: 15626121623
- E-mail: 105852022100090@stu.gzsport.edu.cn
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Critérios de participação
Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.
Critérios de elegibilidade
Idades elegíveis para estudo
- Adulto
Aceita Voluntários Saudáveis
Sim
Descrição
Inclusion Criteria:
- Male basketball students at Guangzhou Sport University.
- Regular participants in basketball training/practice.
- Healthy adults without cardiovascular, hepatic, renal, digestive, neurological, or metabolic diseases.
- Blood pressure within normal range.
- No history of lower extremity musculoskeletal injury within the past 6 months.
- Not currently using any performance-enhancing substances or medications affecting hormones/metabolism.
- Voluntary participation with signed informed consent.
Exclusion Criteria:
- Presence of acute or chronic diseases affecting exercise performance.
- History of deep vein thrombosis or coagulation disorders.
- Presence of skin lesions or infections at the thigh cuff placement site.
- Participation in other concurrent lower extremity strength/power training programs outside the study.
- Use of dietary supplements known to affect muscle metabolism within 4 weeks prior to enrollment.
- Inability to complete the full 6-week intervention and testing protocol.
Plano de estudo
Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.
Como o estudo é projetado?
Detalhes do projeto
- Finalidade Principal: Tratamento
- Alocação: Randomizado
- Modelo Intervencional: Atribuição Paralela
- Mascaramento: Solteiro
Armas e Intervenções
Grupo de Participantes / Braço |
Intervenção / Tratamento |
|---|---|
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Experimental: IPC Group
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475).
Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions.
The intervention was conducted twice per week for 6 weeks.
Cuff placement: at the inguinal crease of the thigh.
Subject position: supine, alternating between left and right legs.
|
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475).
Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions.
The intervention was conducted twice per week for 6 weeks.
Cuff placement: at the inguinal crease of the thigh.
Subject position: supine, alternating between left and right legs.
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Comparador Ativo: Sham Control Group
Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training.
Twice weekly for 6 weeks.
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Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training.
Twice weekly for 6 weeks.
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O que o estudo está medindo?
Medidas de resultados primários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
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Squat Jump (SJ) height
Prazo: Baseline (Week 0) and Post-intervention (Week 8)
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Change from baseline in lower extremity concentric explosive power measured by Smart Jump portable contact mat (cm).
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Baseline (Week 0) and Post-intervention (Week 8)
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Countermovement Jump (CMJ) height
Prazo: Baseline and Week 8
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Change from baseline in lower extremity reactive explosive power without arm swing (cm).
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Baseline and Week 8
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Standing Long Jump
Prazo: Baseline and Week 8
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Change from baseline in lower extremity horizontal explosive power (cm).
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Baseline and Week 8
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T-Test (T-run)
Prazo: Baseline and Week 8
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Change from baseline in multi-directional agility performance (seconds).
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Baseline and Week 8
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3/4 Court Sprint
Prazo: Baseline and Week 8
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Change from baseline in linear sprint speed over 3/4 basketball court distance (~21m, seconds).
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Baseline and Week 8
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Reactive Strength Index (RSI)
Prazo: Baseline and Week 8
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Change from baseline in RSI derived from 30cm drop jump using Smart Jump system (m/s).
The RSI was calculated as jump height divided by ground contact time, with higher values indicating better reactive strength capacity in athletes (i.e., shorter ground contact times and greater jump heights).
The observed range of RSI in the present study was [minimum value]-[maximum value] m/s.
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Baseline and Week 8
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Medidas de resultados secundários
Medida de resultado |
Descrição da medida |
Prazo |
|---|---|---|
|
Blood Lactate Accumulation
Prazo: Baseline and Week 8
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Change in blood lactate accumulation during 10-second maximal load test (mmol/L).
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Baseline and Week 8
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Peak Power (10s Test)
Prazo: Baseline and Week 8
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Change from baseline in peak power output during 10-second maximal load test on Monark 828E cycle ergometer (Watts).
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Baseline and Week 8
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Mean Power (10s Test)
Prazo: Baseline and Week 8
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Change from baseline in mean power output during 10-second maximal load test (Watts).
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Baseline and Week 8
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Testosterone/Cortisol Ratio
Prazo: Baseline and Week 8
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Change from baseline in T/C ratio (×10-²).
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Baseline and Week 8
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Colaboradores e Investigadores
É aqui que você encontrará pessoas e organizações envolvidas com este estudo.
Patrocinador
Publicações e links úteis
A pessoa responsável por inserir informações sobre o estudo fornece voluntariamente essas publicações. Estes podem ser sobre qualquer coisa relacionada ao estudo.
Publicações Gerais
- Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD, Redington AN. Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sports Exerc. 2011 Jul;43(7):1280-6. doi: 10.1249/MSS.0b013e318206845d.
- Bailey TG, Jones H, Gregson W, Atkinson G, Cable NT, Thijssen DH. Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sports Exerc. 2012 Nov;44(11):2084-9. doi: 10.1249/MSS.0b013e318262cb17.
- Cheng CF, Kuo YH, Hsu WC, Chen C, Pan CH. Local and Remote Ischemic Preconditioning Improves Sprint Interval Exercise Performance in Team Sport Athletes. Int J Environ Res Public Health. 2021 Oct 12;18(20):10653. doi: 10.3390/ijerph182010653.
- Chen Y, Yang J, Muradov O, Li X, Lee JKW, Qiu J. Effect of ischemic preconditioning on maximum accumulated oxygen deficit in 400-meter runners. Eur J Sport Sci. 2023 May;23(5):789-796. doi: 10.1080/17461391.2022.2064769. Epub 2022 Apr 25.
- Caru M, Levesque A, Lalonde F, Curnier D. An overview of ischemic preconditioning in exercise performance: A systematic review. J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23.
- Ou Z, Yang L, Zhu H, Weng X, Xu G. Ischemic preconditioning enhances autonomic nervous system modulation during frequency speed of kick test in taekwondo athletes: a randomized crossover study. BMC Sports Sci Med Rehabil. 2026 Feb 12;18(1):136. doi: 10.1186/s13102-026-01602-2.
- Carvalho L, Barroso R. Ischemic Preconditioning Improves Strength Endurance Performance. J Strength Cond Res. 2019 Dec;33(12):3332-3337. doi: 10.1519/JSC.0000000000002846.
Datas de registro do estudo
Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.
Datas Principais do Estudo
Início do estudo (Real)
22 de maio de 2026
Conclusão Primária (Estimado)
15 de julho de 2026
Conclusão do estudo (Estimado)
15 de julho de 2026
Datas de inscrição no estudo
Enviado pela primeira vez
17 de maio de 2026
Enviado pela primeira vez que atendeu aos critérios de CQ
17 de maio de 2026
Primeira postagem (Real)
22 de maio de 2026
Atualizações de registro de estudo
Última Atualização Postada (Real)
26 de maio de 2026
Última atualização enviada que atendeu aos critérios de controle de qualidade
21 de maio de 2026
Última verificação
1 de maio de 2026
Mais Informações
Termos relacionados a este estudo
Palavras-chave
Termos MeSH relevantes adicionais
Outros números de identificação do estudo
- GZSU-IPC-BB-2024
Plano para dados de participantes individuais (IPD)
Planeja compartilhar dados de participantes individuais (IPD)?
INDECISO
Descrição do plano IPD
The data have not been publicly released yet, and contributions may be considered after they are published.
Informações sobre medicamentos e dispositivos, documentos de estudo
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