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- Essai clinique NCT07604948
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period
21 mai 2026 mis à jour par: Ziyue Ou, Guangzhou Sport University
Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period: A Randomized Controlled Trial
This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period.
Thirty-four male collegiate basketball players were randomly assigned to either an IPC group or a placebo control group.
Bilateral lower limb IPC intervention (3 cycles, each consisting of 5-minute ischemia at 220 mmHg and 5-minute reperfusion, twice per week for 6 weeks) was administered before routine basketball training sessions.
Lower limb explosive power, as well as physiological, biochemical, and morphological indices, were assessed before and after the intervention.
Aperçu de l'étude
Statut
Recrutement
Les conditions
Intervention / Traitement
Description détaillée
Background: Lower limb explosive power is crucial for basketball performance, and effective recovery strategies are key to maintaining training quality.
Ischemic preconditioning (IPC) is a non-invasive, economical, and safe method that triggers endogenous protective mechanisms through brief ischemia-reperfusion cycles, showing potential in enhancing athletic performance and metabolic efficiency.
However, the effects of IPC on lower limb explosive power during post-match recovery in basketball players remain understudied.
Objective: To investigate the effects of a 6-week repeated remote ischemic preconditioning on lower limb explosive power, phosphagen energy system capacity, and physical recovery in male college basketball players.
Design: A randomized, parallel-group, placebo-controlled trial with concealed allocation.
Participants were randomly assigned to either the IPC experimental group (n=17) or the placebo control group (n=17).
Both groups participated in the same regular basketball sessions.
The experimental group received bilateral thigh IPC intervention (3×5 minutes, 220 mmHg) before each training session, while the control group received a placebo intervention (3×5 minutes, 20 mmHg).
The intervention was administered twice a week for 6 weeks (30 minutes per session).
Secondary endpoints: Urinary creatinine coefficient, 10-second maximal load test (blood lactate increment, peak power, mean power), hematological parameters (red blood cell count, hemoglobin, hematocrit, white blood cell count), serum testosterone, cortisol, testosterone/cortisol ratio, body composition (body weight, body fat percentage, BMI), and training load monitoring (heart rate, RPE, urine protein).
Type d'étude
Interventionnel
Inscription (Estimé)
34
Phase
- N'est pas applicable
Contacts et emplacements
Cette section fournit les coordonnées de ceux qui mènent l'étude et des informations sur le lieu où cette étude est menée.
Coordonnées de l'étude
- Nom: Ziyue Ou, PHD
- Numéro de téléphone: +8615626121623
- E-mail: 105852022100090@stu.gzsport.edu.cn
Lieux d'étude
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Guangdong
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Guangzhou, Guangdong, Chine, 510430
- Recrutement
- Guangzhou Sport University
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Contact:
- Ziyue Ou, PHD
- Numéro de téléphone: 15626121623
- E-mail: 105852022100090@stu.gzsport.edu.cn
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Critères de participation
Les chercheurs recherchent des personnes qui correspondent à une certaine description, appelée critères d'éligibilité. Certains exemples de ces critères sont l'état de santé général d'une personne ou des traitements antérieurs.
Critère d'éligibilité
Âges éligibles pour étudier
- Adulte
Accepte les volontaires sains
Oui
La description
Inclusion Criteria:
- Male basketball students at Guangzhou Sport University.
- Regular participants in basketball training/practice.
- Healthy adults without cardiovascular, hepatic, renal, digestive, neurological, or metabolic diseases.
- Blood pressure within normal range.
- No history of lower extremity musculoskeletal injury within the past 6 months.
- Not currently using any performance-enhancing substances or medications affecting hormones/metabolism.
- Voluntary participation with signed informed consent.
Exclusion Criteria:
- Presence of acute or chronic diseases affecting exercise performance.
- History of deep vein thrombosis or coagulation disorders.
- Presence of skin lesions or infections at the thigh cuff placement site.
- Participation in other concurrent lower extremity strength/power training programs outside the study.
- Use of dietary supplements known to affect muscle metabolism within 4 weeks prior to enrollment.
- Inability to complete the full 6-week intervention and testing protocol.
Plan d'étude
Cette section fournit des détails sur le plan d'étude, y compris la façon dont l'étude est conçue et ce que l'étude mesure.
Comment l'étude est-elle conçue ?
Détails de conception
- Objectif principal: Traitement
- Répartition: Randomisé
- Modèle interventionnel: Affectation parallèle
- Masquage: Seul
Armes et Interventions
Groupe de participants / Bras |
Intervention / Traitement |
|---|---|
|
Expérimental: IPC Group
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475).
Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions.
The intervention was conducted twice per week for 6 weeks.
Cuff placement: at the inguinal crease of the thigh.
Subject position: supine, alternating between left and right legs.
|
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475).
Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions.
The intervention was conducted twice per week for 6 weeks.
Cuff placement: at the inguinal crease of the thigh.
Subject position: supine, alternating between left and right legs.
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Comparateur actif: Sham Control Group
Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training.
Twice weekly for 6 weeks.
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Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training.
Twice weekly for 6 weeks.
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Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
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Squat Jump (SJ) height
Délai: Baseline (Week 0) and Post-intervention (Week 8)
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Change from baseline in lower extremity concentric explosive power measured by Smart Jump portable contact mat (cm).
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Baseline (Week 0) and Post-intervention (Week 8)
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Countermovement Jump (CMJ) height
Délai: Baseline and Week 8
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Change from baseline in lower extremity reactive explosive power without arm swing (cm).
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Baseline and Week 8
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Standing Long Jump
Délai: Baseline and Week 8
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Change from baseline in lower extremity horizontal explosive power (cm).
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Baseline and Week 8
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T-Test (T-run)
Délai: Baseline and Week 8
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Change from baseline in multi-directional agility performance (seconds).
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Baseline and Week 8
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3/4 Court Sprint
Délai: Baseline and Week 8
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Change from baseline in linear sprint speed over 3/4 basketball court distance (~21m, seconds).
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Baseline and Week 8
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Reactive Strength Index (RSI)
Délai: Baseline and Week 8
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Change from baseline in RSI derived from 30cm drop jump using Smart Jump system (m/s).
The RSI was calculated as jump height divided by ground contact time, with higher values indicating better reactive strength capacity in athletes (i.e., shorter ground contact times and greater jump heights).
The observed range of RSI in the present study was [minimum value]-[maximum value] m/s.
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Baseline and Week 8
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Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
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Blood Lactate Accumulation
Délai: Baseline and Week 8
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Change in blood lactate accumulation during 10-second maximal load test (mmol/L).
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Baseline and Week 8
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Peak Power (10s Test)
Délai: Baseline and Week 8
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Change from baseline in peak power output during 10-second maximal load test on Monark 828E cycle ergometer (Watts).
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Baseline and Week 8
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Mean Power (10s Test)
Délai: Baseline and Week 8
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Change from baseline in mean power output during 10-second maximal load test (Watts).
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Baseline and Week 8
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Testosterone/Cortisol Ratio
Délai: Baseline and Week 8
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Change from baseline in T/C ratio (×10-²).
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Baseline and Week 8
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Collaborateurs et enquêteurs
C'est ici que vous trouverez les personnes et les organisations impliquées dans cette étude.
Parrainer
Publications et liens utiles
La personne responsable de la saisie des informations sur l'étude fournit volontairement ces publications. Il peut s'agir de tout ce qui concerne l'étude.
Publications générales
- Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Wells GD, Redington AN. Remote preconditioning improves maximal performance in highly trained athletes. Med Sci Sports Exerc. 2011 Jul;43(7):1280-6. doi: 10.1249/MSS.0b013e318206845d.
- Bailey TG, Jones H, Gregson W, Atkinson G, Cable NT, Thijssen DH. Effect of ischemic preconditioning on lactate accumulation and running performance. Med Sci Sports Exerc. 2012 Nov;44(11):2084-9. doi: 10.1249/MSS.0b013e318262cb17.
- Cheng CF, Kuo YH, Hsu WC, Chen C, Pan CH. Local and Remote Ischemic Preconditioning Improves Sprint Interval Exercise Performance in Team Sport Athletes. Int J Environ Res Public Health. 2021 Oct 12;18(20):10653. doi: 10.3390/ijerph182010653.
- Chen Y, Yang J, Muradov O, Li X, Lee JKW, Qiu J. Effect of ischemic preconditioning on maximum accumulated oxygen deficit in 400-meter runners. Eur J Sport Sci. 2023 May;23(5):789-796. doi: 10.1080/17461391.2022.2064769. Epub 2022 Apr 25.
- Caru M, Levesque A, Lalonde F, Curnier D. An overview of ischemic preconditioning in exercise performance: A systematic review. J Sport Health Sci. 2019 Jul;8(4):355-369. doi: 10.1016/j.jshs.2019.01.008. Epub 2019 Jan 23.
- Ou Z, Yang L, Zhu H, Weng X, Xu G. Ischemic preconditioning enhances autonomic nervous system modulation during frequency speed of kick test in taekwondo athletes: a randomized crossover study. BMC Sports Sci Med Rehabil. 2026 Feb 12;18(1):136. doi: 10.1186/s13102-026-01602-2.
- Carvalho L, Barroso R. Ischemic Preconditioning Improves Strength Endurance Performance. J Strength Cond Res. 2019 Dec;33(12):3332-3337. doi: 10.1519/JSC.0000000000002846.
Dates d'enregistrement des études
Ces dates suivent la progression des dossiers d'étude et des soumissions de résultats sommaires à ClinicalTrials.gov. Les dossiers d'étude et les résultats rapportés sont examinés par la Bibliothèque nationale de médecine (NLM) pour s'assurer qu'ils répondent à des normes de contrôle de qualité spécifiques avant d'être publiés sur le site Web public.
Dates principales de l'étude
Début de l'étude (Réel)
22 mai 2026
Achèvement primaire (Estimé)
15 juillet 2026
Achèvement de l'étude (Estimé)
15 juillet 2026
Dates d'inscription aux études
Première soumission
17 mai 2026
Première soumission répondant aux critères de contrôle qualité
17 mai 2026
Première publication (Réel)
22 mai 2026
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
26 mai 2026
Dernière mise à jour soumise répondant aux critères de contrôle qualité
21 mai 2026
Dernière vérification
1 mai 2026
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- GZSU-IPC-BB-2024
Plan pour les données individuelles des participants (IPD)
Prévoyez-vous de partager les données individuelles des participants (DPI) ?
INDÉCIS
Description du régime IPD
The data have not been publicly released yet, and contributions may be considered after they are published.
Informations sur les médicaments et les dispositifs, documents d'étude
Étudie un produit pharmaceutique réglementé par la FDA américaine
Non
Étudie un produit d'appareil réglementé par la FDA américaine
Non
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