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Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period

21 mei 2026 bijgewerkt door: Ziyue Ou, Guangzhou Sport University

Effect of Ischemic Preconditioning on Lower Extremity Motor Ability and Recovery in Basketball Players During Post-Match Recovery Period: A Randomized Controlled Trial

This study aimed to evaluate the effects of ischemic preconditioning on lower limb explosive power and post-exercise recovery in basketball players during a 6-week post-season recovery training period. Thirty-four male collegiate basketball players were randomly assigned to either an IPC group or a placebo control group. Bilateral lower limb IPC intervention (3 cycles, each consisting of 5-minute ischemia at 220 mmHg and 5-minute reperfusion, twice per week for 6 weeks) was administered before routine basketball training sessions. Lower limb explosive power, as well as physiological, biochemical, and morphological indices, were assessed before and after the intervention.

Studie Overzicht

Toestand

Werving

Conditie

Interventie / Behandeling

Gedetailleerde beschrijving

Background: Lower limb explosive power is crucial for basketball performance, and effective recovery strategies are key to maintaining training quality. Ischemic preconditioning (IPC) is a non-invasive, economical, and safe method that triggers endogenous protective mechanisms through brief ischemia-reperfusion cycles, showing potential in enhancing athletic performance and metabolic efficiency. However, the effects of IPC on lower limb explosive power during post-match recovery in basketball players remain understudied. Objective: To investigate the effects of a 6-week repeated remote ischemic preconditioning on lower limb explosive power, phosphagen energy system capacity, and physical recovery in male college basketball players. Design: A randomized, parallel-group, placebo-controlled trial with concealed allocation. Participants were randomly assigned to either the IPC experimental group (n=17) or the placebo control group (n=17). Both groups participated in the same regular basketball sessions. The experimental group received bilateral thigh IPC intervention (3×5 minutes, 220 mmHg) before each training session, while the control group received a placebo intervention (3×5 minutes, 20 mmHg). The intervention was administered twice a week for 6 weeks (30 minutes per session). Secondary endpoints: Urinary creatinine coefficient, 10-second maximal load test (blood lactate increment, peak power, mean power), hematological parameters (red blood cell count, hemoglobin, hematocrit, white blood cell count), serum testosterone, cortisol, testosterone/cortisol ratio, body composition (body weight, body fat percentage, BMI), and training load monitoring (heart rate, RPE, urine protein).

Studietype

Ingrijpend

Inschrijving (Geschat)

34

Fase

  • Niet toepasbaar

Contacten en locaties

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Studiecontact

Studie Locaties

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

  • Volwassen

Accepteert gezonde vrijwilligers

Ja

Beschrijving

Inclusion Criteria:

  • Male basketball students at Guangzhou Sport University.
  • Regular participants in basketball training/practice.
  • Healthy adults without cardiovascular, hepatic, renal, digestive, neurological, or metabolic diseases.
  • Blood pressure within normal range.
  • No history of lower extremity musculoskeletal injury within the past 6 months.
  • Not currently using any performance-enhancing substances or medications affecting hormones/metabolism.
  • Voluntary participation with signed informed consent.

Exclusion Criteria:

  • Presence of acute or chronic diseases affecting exercise performance.
  • History of deep vein thrombosis or coagulation disorders.
  • Presence of skin lesions or infections at the thigh cuff placement site.
  • Participation in other concurrent lower extremity strength/power training programs outside the study.
  • Use of dietary supplements known to affect muscle metabolism within 4 weeks prior to enrollment.
  • Inability to complete the full 6-week intervention and testing protocol.

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Behandeling
  • Toewijzing: Gerandomiseerd
  • Interventioneel model: Parallelle opdracht
  • Masker: Enkel

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Experimenteel: IPC Group
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475). Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions. The intervention was conducted twice per week for 6 weeks. Cuff placement: at the inguinal crease of the thigh. Subject position: supine, alternating between left and right legs.
Apparaat: Ischemic Preconditioning
Bilateral thigh compression was applied using a Theratools pneumatic cuff (T-bfr-0475). Three cycles, each consisting of 5 minutes of ischemia (pressure 220 mmHg) and 5 minutes of reperfusion (total 30 minutes), were performed before regular basketball training sessions. The intervention was conducted twice per week for 6 weeks. Cuff placement: at the inguinal crease of the thigh. Subject position: supine, alternating between left and right legs.
Actieve vergelijker: Sham Control Group
Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training. Twice weekly for 6 weeks.
Apparaat: Placebo Ischemic Preconditioning
Identical procedure to IPC group except cuff pressure maintained at 20 mmHg (non-ischemic), applied before regular basketball training. Twice weekly for 6 weeks.

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Squat Jump (SJ) height
Tijdsspanne: Baseline (Week 0) and Post-intervention (Week 8)
Change from baseline in lower extremity concentric explosive power measured by Smart Jump portable contact mat (cm).
Baseline (Week 0) and Post-intervention (Week 8)
Countermovement Jump (CMJ) height
Tijdsspanne: Baseline and Week 8
Change from baseline in lower extremity reactive explosive power without arm swing (cm).
Baseline and Week 8
Standing Long Jump
Tijdsspanne: Baseline and Week 8
Change from baseline in lower extremity horizontal explosive power (cm).
Baseline and Week 8
T-Test (T-run)
Tijdsspanne: Baseline and Week 8
Change from baseline in multi-directional agility performance (seconds).
Baseline and Week 8
3/4 Court Sprint
Tijdsspanne: Baseline and Week 8
Change from baseline in linear sprint speed over 3/4 basketball court distance (~21m, seconds).
Baseline and Week 8
Reactive Strength Index (RSI)
Tijdsspanne: Baseline and Week 8
Change from baseline in RSI derived from 30cm drop jump using Smart Jump system (m/s). The RSI was calculated as jump height divided by ground contact time, with higher values indicating better reactive strength capacity in athletes (i.e., shorter ground contact times and greater jump heights). The observed range of RSI in the present study was [minimum value]-[maximum value] m/s.
Baseline and Week 8

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Blood Lactate Accumulation
Tijdsspanne: Baseline and Week 8
Change in blood lactate accumulation during 10-second maximal load test (mmol/L).
Baseline and Week 8
Peak Power (10s Test)
Tijdsspanne: Baseline and Week 8
Change from baseline in peak power output during 10-second maximal load test on Monark 828E cycle ergometer (Watts).
Baseline and Week 8
Mean Power (10s Test)
Tijdsspanne: Baseline and Week 8
Change from baseline in mean power output during 10-second maximal load test (Watts).
Baseline and Week 8
Testosterone/Cortisol Ratio
Tijdsspanne: Baseline and Week 8
Change from baseline in T/C ratio (×10-²).
Baseline and Week 8

Medewerkers en onderzoekers

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Sponsor

Guangzhou Sport University

Publicaties en nuttige links

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Algemene publicaties

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Werkelijk)

22 mei 2026

Primaire voltooiing (Geschat)

15 juli 2026

Studie voltooiing (Geschat)

15 juli 2026

Studieregistratiedata

Eerst ingediend

17 mei 2026

Eerst ingediend dat voldeed aan de QC-criteria

17 mei 2026

Eerst geplaatst (Werkelijk)

22 mei 2026

Updates van studierecords

Laatste update geplaatst (Werkelijk)

26 mei 2026

Laatste update ingediend die voldeed aan QC-criteria

21 mei 2026

Laatst geverifieerd

1 mei 2026

Meer informatie

Termen gerelateerd aan deze studie

Trefwoorden

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

  • GZSU-IPC-BB-2024

Plan Individuele Deelnemersgegevens (IPD)

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Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Nee

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

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