Effects of Whole-Body HIIT and Moderate Continuous Exercise on Immune Function (WBHIIT-IMM)
Effects of Whole-Body High-Intensity Interval Training and Moderate-Intensity Continuous Exercise on Immune Function in Recreationally Active Men
연구 개요
상태
상세 설명
This study was designed as a two-arm, parallel-group, randomized controlled trial. A total of 20 recreationally active male participants were randomly assigned to either the Whole Body High-Intensity Interval Training (WB-HIIT) group or the Moderate-Intensity Continuous Training (MICT) group. The intervention lasted 12 weeks and involved supervised training sessions multiple times a week.
The WB-HIIT protocol consisted of repeated high-intensity whole-body exercises performed at near-maximum effort with intermittent rest periods, while the MICT group performed moderate-intensity continuous aerobic exercise. Immune function was assessed through selected hematological and biochemical markers collected at baseline and post-intervention. In addition, physical performance variables were evaluated to examine secondary adaptations to different exercise modalities. The primary aim of the study was to compare the effects of WB-HIIT and MICT on immune system responses, while secondary outcomes included changes in exercise performance. This study provides insights into how different training intensities affect immune regulation in individuals who are active in their leisure time.
연구 유형
등록 (실제)
단계
- 해당 없음
연락처 및 위치
연구 장소
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Merkez
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Bitlis, Merkez, 터키 (Türkiye), 13100
- Bitlis Eren University
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참여기준
자격 기준
공부할 수 있는 나이
- 성인
- 고령자
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
Healthy male adults Aged 18-25 years Not engaged in regular structured exercise training (>3 sessions/week) VO₂max within normal healthy range Willingness to participate and provide informed consent No acute or chronic inflammatory, metabolic, or cardiovascular disease
Exclusion Criteria:
Female participants (not included in study design) Smoking or alcohol abuse Use of anti-inflammatory or immunomodulatory drugs Participation in regular high-intensity training programs Musculoskeletal limitations preventing exercise testing or training Acute infection within last 2 weeks Chronic metabolic, cardiovascular, or autoimmune diseases
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 치료
- 할당: 무작위
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
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실험적: Whole-Body HIIT
Participants will perform Whole-Body High-Intensity Interval Training (WB-HIIT) protocol.
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Whole-body high-intensity interval training protocol performed under supervision.
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활성 비교기: MICT
Participants will perform Moderate-Intensity Continuous Training (MICT) protocol.
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Moderate-intensity continuous training protocol performed under supervision.
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연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Peripheral immune cell counts
기간: Baseline and 8 weeks (post-intervention)
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Changes in peripheral blood leukocyte, lymphocyte subsets, neutrophil, and monocyte counts from baseline to post-intervention (8 weeks).
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Baseline and 8 weeks (post-intervention)
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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Inflammatory cytokine levels
기간: Baseline and 8 weeks (post-intervention)
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Changes in serum IL-6, TNF-α, and CRP levels from baseline to post-intervention (8 weeks).
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Baseline and 8 weeks (post-intervention)
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Immunoglobulin levels
기간: Baseline and 8 weeks (post-intervention)
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Changes in serum immunoglobulin (IgA, IgG, IgM) concentrations from baseline to post-intervention (8 weeks).
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Baseline and 8 weeks (post-intervention)
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Cortisol levels
기간: Baseline and 8 weeks (post-intervention)
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Changes in serum cortisol levels as a marker of exercise-induced stress response from baseline to post-intervention (8 weeks).
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Baseline and 8 weeks (post-intervention)
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Maximal oxygen uptake (VO₂max)
기간: Baseline and 8 weeks (post-intervention)
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Changes in VO₂max measured by cardiopulmonary exercise testing from baseline to post-intervention.
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Baseline and 8 weeks (post-intervention)
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공동 작업자 및 조사자
수사관
- 수석 연구원: Melih Çalışır, PhD, Bitlis Eren Üniversitesi University
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (실제)
연구 완료 (실제)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- 2020-189
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
IPD 계획 설명
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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