Evaluating the Acceptability of AI-Personalized Virtual Reality Picture Books for Hospitalized Pediatric Patients (LLM-audiobook)
Hospitalization strips pediatric patients of the environments, objects, and people that shape their daily lives. Hospitalized pediatric patients routinely experience painful procedures, psychological distress, boredom, and a disorienting loss of personal identity. These experiences measurably worsen anxiety, reduce cooperation with care, and diminish the quality of the inpatient experience for both patients and families. Immersive digital interventions, including VR and tablet-based experiences, have emerged as a promising class of tools for addressing these challenges. Prior studies from The Stanford Chariot Program have demonstrated that digitally delivered, patient-centered experiences can meaningfully reduce procedural anxiety and improve engagement in hospitalized children.
Yet, an important limitation persists in these technologies - current digital interventions largely remain in one-size-fits-all formats. Every child receives the same content, regardless of who they are, what they love, or what makes them feel at home in the world. This design limits therapeutic relevance, constrains engagement, and represents a missed opportunity to engage children, reduce anxiety, and enhance their quality of life during hospital stays.
연구 개요
연구 유형
등록 (추정된)
단계
- 해당 없음
연락처 및 위치
연구 연락처
- 이름: Samuel Rodriguez, MD
- 전화번호: 650-723-5728
- 이메일: sr1@stanford.edu
연구 연락처 백업
- 이름: ManYee Suen, MMedSc
- 전화번호: 650-723-5728
- 이메일: smy822@stanford.edu
참여기준
자격 기준
공부할 수 있는 나이
- 어린이
건강한 자원 봉사자를 받아들입니다
설명
Inclusion Criteria:
- Between age 9-17
- Current admission in inpatient unit
- Able to understand and interact with a virtual reality audiobook in English
Exclusion Criteria:
- Legal guardian not present to obtain consent
- Significant cognitive impairment and/or developmental delay
- History of seizures
- History of severe motion sickness
- Severe visual or motor impairment limiting picture book participation
- Child with active infection of the face or hand
- Acute medical instability
- Inability to understand English
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 지지 요법
- 할당: 해당 없음
- 중재 모델: 단일 그룹 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
|
실험적: Pediatric patient
|
Develop and refine a two-stage personalization LLM pipeline: (1) a structured brief interview template and (2) an LLM prompt chain for content generation. The interview instrument will be a structured guide (~20 minutes) capturing details about the child's background, interests, and aspirations. All information collected during the interview will be deidentified prior to being passed into the LLM. Content Generation: Deidentified interview responses will be input to a standardized LLM prompt pipeline. The pipeline generates a structured patient profile that interprets the participant's interests, personality, and preferences, then uses that profile to produce a personalized narrative, formatted as a picture book story. AI voice synthesis will generate an audio narration of the story. AI image generation tools will produce a set of 6-10 accompanying illustrations. The final product - a synchronized audio picture book - will be delivered via VR headset at bedside. |
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
Determine the acceptability of the Large Language Model generated audiobook
기간: Immediately after intervention
|
Semi-structured focus group interviews conducted in person immediately after intervention.
Six core questions plus probing prompts assessing attitudes and opinions, and perceptions of the intervention experience
|
Immediately after intervention
|
2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
|
To assess the degree to which participants identified with the protagonist of the personalized audio picture book.
기간: Immediately after intervention
|
Participants will complete the Cohen Identification Scale following the VR experience. Items are answered using a 5-point Likert scale ranging from 1 = strongly disagree to 5 = strongly agree. Item responses will be averaged to generate a composite score, with higher scores indicating greater identification with the main character. |
Immediately after intervention
|
|
To assess emotional state using Positive and Negative Affect Schedule - Child Form (PANAS-C)
기간: baseline, Immediately after intervention
|
The PANAS-C measures the degree to which children experience positive and negative affective states, yielding two subscale scores: Positive Affect and Negative Affect.
Items are answered using a 5-point Likert scale ranging from 1 = very slightly or not at all to 5 = extremely.
Higher Positive Affect (PA) Score indicates a higher level of positive emotions while higher Negative Affect (NA) Score indicates a higher level of negative emotions.
|
baseline, Immediately after intervention
|
|
To assess subjective wellbeing using the World Health Organization-Five Child Well-Being Index (WHO-5)
기간: baseline, Immediately after intervention
|
The WHO-5 is a brief, validated self-report measure assessing current mental wellbeing across five positively worded items covering mood, relaxation, energy, rest, and daily interest.
The WHO-5 instructs respondents to rate how they have felt "over the last two weeks,"; the scale will be modified in this study to ask the participants to reflect on their current state.
Items are answered using a 5-point Likert scale ranging from 0 = never to 5 = all of the time.
To calculate the overall wellbeing score, the responses to the five items are summed and the total is multiplied by 5, yielding a final score between 0 and 100.
Higher scores reflect higher levels of wellbeing.
|
baseline, Immediately after intervention
|
공동 작업자 및 조사자
수사관
- 연구 책임자: Samuel Rodriguez, MD, Stanford University
- 수석 연구원: Thomas Caruso, MD,PhD, Stanford University
연구 기록 날짜
연구 주요 날짜
연구 시작 (추정된)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
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