The Use of Infrared Cameras for Detecting Juvenile Idiopathic Arthritis (InfraAJI)
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children, causing persistent joint inflammation, pain, and functional impairment. Current monitoring relies on clinical scores, laboratory markers, and imaging, which are often resource intensive. Infrared thermography (IRT) is a non-invasive, radiation-free method that detects skin temperature changes potentially reflecting joint inflammation. Evidence in pediatric populations is limited, but IRT could provide an objective, reproducible, and child-friendly tool. This study aims to evaluate IRT's diagnostic accuracy by comparing it with clinical scores, laboratory markers, and ultrasound Doppler, to assess its utility as a complementary monitoring tool.
Patients with JIA will undergo clinical examination, routine blood tests, and IRT at baseline, 1 month, and 3 months. Control patients will participate in a single IRT session and, a CRP/ESR/blood test; if a biological workup is already planned as part of their routine care, existing results will be collected, and no additional sampling will be performed. IRT will follow a standardized protocol, including an acclimatization period, predefined positioning, and acquisition of three consecutive images per joint. After completion of the study, JIA patients will resume their standard-of-care follow-up.
연구 개요
상태
연구 유형
등록 (추정된)
단계
- 해당 없음
연락처 및 위치
연구 연락처
- 이름: Djamal-Dine DJEDDI, Pr
- 전화번호: 33+322035590
- 이메일: Djeddi.Djamal-Dine@chu-amiens.fr
연구 장소
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Amiens, 프랑스, 80480
- 모병
- CHRU Amiens
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연락하다:
- Djamal-Dine Djeddi, Pr
- 전화번호: 33+322087632
- 이메일: djeddi.djamal-dine@chu-amiens.fr
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부수사관:
- Maud ULLMO ULLMO, MD
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참여기준
자격 기준
공부할 수 있는 나이
건강한 자원 봉사자를 받아들입니다
연구 대상 성별
설명
Inclusion Criteria:
- children aged 2-16 years with clinically suspected arthritis affecting the knee, ankle, wrist, or hand, irrespective of disease stage,
- control group : children with non-inflammatory conditions and no history of autoimmune or inflammatory disease.
Exclusion Criteria:
- other inflammatory or non-inflammatory diseases or recent trauma/surgery explaining joint symptoms,
- local skin conditions interfering with infrared imaging, and treatments or comorbidities likely to alter joint or body temperature.
공부 계획
연구는 어떻게 설계됩니까?
디자인 세부사항
- 주 목적: 상영
- 할당: 무작위화되지 않음
- 중재 모델: 병렬 할당
- 마스킹: 없음(오픈 라벨)
무기와 개입
참가자 그룹 / 팔 |
개입 / 치료 |
|---|---|
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실험적: Patients with JIA
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Patients with JIA will undergo a standardized evaluation including a clinical joint examination, routine blood tests (CRP, NFS, ionogram, liver function, coagulation), and IRT of selected joints |
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활성 비교기: Control patients
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Control patients will undergo a single IRT session and a minimal blood test (CRP, ESP, blood count). IRT will be performed under controlled conditions with a defined joint positioning, 15-30 minutes of acclimatization, and acquisition of three consecutive images per joint. |
연구는 무엇을 측정합니까?
주요 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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variation of IRT measure between both groups
기간: at baseline
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variation of IRT measure between both groups |
at baseline
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variation of IRT measure between both groups
기간: at 1 month
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variation of IRT measure between both groups |
at 1 month
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variation of IRT measure between both groups
기간: at 3 months
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variation of IRT measure between both groups |
at 3 months
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2차 결과 측정
결과 측정 |
측정값 설명 |
기간 |
|---|---|---|
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longitudinal changes in thermographic measurements
기간: at 3 months
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longitudinal changes in thermographic measurements by comparing temperature differences (ΔT) between baseline (D0) and 3 months |
at 3 months
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correlation of longitudinal changes in thermographic measurements with clinical parameters
기간: at 3 months
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at 3 months
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correlation of longitudinal changes in thermographic measurements with functional parameters
기간: at 3 months
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at 3 months
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correlation of longitudinal changes in thermographic measurements with biological parameters
기간: at 3 months
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at 3 months
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correlation of diagnostic performance of IRT with clinical examination
기간: at 3 months
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at 3 months
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correlation of diagnostic performance of IRT with ultrasounds
기간: at 3 months
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at 3 months
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correlation of diagnostic performance of IRT with MRI
기간: at 3 months
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at 3 months
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reproducibility of IRT measurements
기간: at 3 months
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at 3 months
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공동 작업자 및 조사자
연구 기록 날짜
연구 주요 날짜
연구 시작 (실제)
기본 완료 (추정된)
연구 완료 (추정된)
연구 등록 날짜
최초 제출
QC 기준을 충족하는 최초 제출
처음 게시됨 (실제)
연구 기록 업데이트
마지막 업데이트 게시됨 (실제)
QC 기준을 충족하는 마지막 업데이트 제출
마지막으로 확인됨
추가 정보
이 연구와 관련된 용어
기타 연구 ID 번호
- PI2026_843_0096
개별 참가자 데이터(IPD) 계획
개별 참가자 데이터(IPD)를 공유할 계획입니까?
약물 및 장치 정보, 연구 문서
미국 FDA 규제 의약품 연구
미국 FDA 규제 기기 제품 연구
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