Rediscovering the classic osteopathic literature to advance contemporary patient-oriented research: A new look at diabetes mellitus

John C Licciardone, John C Licciardone

Abstract

Patient care experiences represent opportunities for establishing theories, testable hypotheses, and data to assess the potential use of osteopathic manipulative treatment in various disease conditions. The re-analysis of Bandeen's 1949 raw data described herein summarizes the effects of osteopathic manipulative treatment involving pancreatic stimulatory and inhibitory techniques in diabetic and non-diabetic patients seen over a 25-year period of clinical practice. Bandeen's data demonstrate a reduction in blood glucose levels at 30 and 60 minutes following pancreatic stimulation in 150 diabetic patients, and an elevation in blood glucose levels at 30 and 60 minutes following pancreatic inhibition in 40 non-diabetic patients. Such patient-oriented research conducted during the classic era of osteopathy in the United States provides a foundation and data for generating hypotheses about the potential mechanisms of action of osteopathic manipulative treatment. Osteopathic investigators would be well-served to rediscover the classic osteopathic literature to help advance contemporary evidence-based medicine.

Figures

Figure 1
Figure 1
Mean blood glucose levels over time in diabetic patients receiving osteopathic manipulative treatment to stimulate pancreatic functioning. Baseline values are for fasting blood glucose (based on 150, 121, and 86 observations, respectively, at 0, 30, and 60 minutes post-pancreatic stimulation).
Figure 2
Figure 2
Mean blood glucose levels over time in non-diabetic patients receiving osteopathic manipulative treatment to inhibit pancreatic functioning. Baseline values are for random (non-fasting) blood glucose (based on 40 observations each at 0, 30, and 60 minutes post-pancreatic inhibition).

References

    1. Meyer CT, Price A. The crisis in osteopathic medicine. Acad Med. 1992;67:810–816. doi: 10.1097/00001888-199212000-00002.
    1. Meyer CT, Price A. Osteopathic medicine: a call for reform. J Am Osteopath Assoc. 1993;93:473–485.
    1. Midcareer Investigator Award in Patient-Oriented Research (K24)
    1. Castlio Y, Ferris-Swift L. Effects of splenic stimulation in normal individuals on the actual and differential blood cell count, and opsonic index. Coll J Kansas City Coll Osteopath Surg. 1932;16:111–120.
    1. Castlio Y, Ferris-Swift L. The effect of direct splenic stimulation on the cells and antibody content of the blood stream in acute infectious disease. Coll J Kansas City Coll Osteopath Surg. 1934;18:196–211.
    1. Smith RK. One hundred thousand cases of influenza with a death rate of one-fortieth of that officially reported under conventional medical treatment. J Am Osteopath Assoc. 1920;19:172–175.
    1. Noll DR, Johnson JC. Revisiting Castlio and Ferris-Swift's experiments testing the effects of splenic pump in normal individuals. Int J Osteopath Med. 2005;8:124–130. doi: 10.1016/j.ijosm.2005.11.002.
    1. Noll DR, Johnson JC, Brooks JE. Revisiting Castlio and Ferris-Swift's experiments on direct splenic stimulation in patients with acute infectious disease. J Am Osteopath Assoc. 2008;108:71–79.
    1. Hruby RJ, Hoffman KN. Avian influenza: an osteopathic component to treatment. Osteopath Med Prim Care. 2007;1:10. doi: 10.1186/1750-4732-1-10.
    1. Sanderlin BW, Licciardone JC. Osteopathic manipulative treatment for pandemic influenza: many questions, few answers. Osteopath Med Prim Care. 2007;1:12. doi: 10.1186/1750-4732-1-12.
    1. American Osteopathic Association . Fact Sheet 2006. Chicago, IL; 2006.
    1. Bandeen SG. Diabetes: report covering twenty-five years research on stimulation of pancreas, blood chemical changes. Osteopath Prof. 1949;17:11–15. 38, 40, 42, 44, 46–47.
    1. National Institutes of Health Diagnosis of Diabetes. US Department of Health and Human Services,: Publication No 05-4642. 2005.
    1. Centers for Disease Control and Prevention . National diabetes fact sheet: general information and national estimates on diabetes in the United States, 2003. Rev. Atlanta, GA: U.S. Department of Health and Human Services; 2004.
    1. Segal KR. Type 2 diabetes and disease management: exploring the connections. Dis Manag. 2004;7:S11–22. doi: 10.1089/1093507042317125.
    1. American Diabetes Association Economic costs of diabetes in the U.S. in 2002. Diabetes Care. 2003;26:917–932. doi: 10.2337/diacare.26.7.2194.
    1. Bergman RN. Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes. 1989;38:1512–1527. doi: 10.2337/diabetes.38.12.1512.
    1. Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest. 1999;104:787–794. doi: 10.1172/JCI7231.
    1. Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet. 2005;365:1333–1346. doi: 10.1016/S0140-6736(05)61032-X.
    1. Kristiansen OP, Mandrup-Poulsen T. Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes. 2005;54:S114–124. doi: 10.2337/diabetes.54.suppl_2.S114.
    1. Mantyselka P, Miettola J, Niskanen L, Kumpusalo E. Chronic pain, impaired glucose tolerance and diabetes: A community-based study. Pain. 2007
    1. Licciardone JC, Brimhall AK, King LN. Osteopathic manipulative treatment for low back pain: a systematic review and meta-analysis of randomized controlled trials. BMC Musculoskelet Disord. 2005;6:43. doi: 10.1186/1471-2474-6-43.
    1. Beal MC. Viscerosomatic reflexes: a review. J Am Osteopath Assoc. 1985;85:786–801.
    1. Hodge LM, King HH, Williams AG, Jr, Reder SJ, Belavadi T, Simecka JW, Stoll ST, Downey HF. Abdominal lymphatic pump treatment increases leukocyte count and flux in thoracic duct lymph. Lymphat Res Biol. 2007;5:127–133. doi: 10.1089/lrb.2007.1001.
    1. Gwirtz PA, Dickey J, Vick D, Williams MA, Foresman B. Viscerosomatic interaction induced by myocardial ischemia in conscious dogs. J Appl Physiol. 2007;103:511–517. doi: 10.1152/japplphysiol.00495.2006.
    1. Meltzer KR, Standley PR. Modeled repetitive motion strain and indirect osteopathic manipulative techniques in regulation of human fibroblast proliferation and interleukin secretion. J Am Osteopath Assoc. 2007;107:527–536.
    1. Degenhardt BF, Darmani NA, Johnson JC, Towns LC, Rhodes DC, Trinh C, McClanahan B, DiMarzo V. Role of osteopathic manipulative treatment in altering pain biomarkers: a pilot study. J Am Osteopath Assoc. 2007;107:387–400.

Source: PubMed

3
구독하다