Validation of a short disease specific quality of life scale for hemifacial spasm: correlation with SF-36
E K Tan, S Fook-Chong, S-Y Lum, J Thumboo, E K Tan, S Fook-Chong, S-Y Lum, J Thumboo
Abstract
Background: A short, practical, and validated quality of life (QoL) scale for hemifacial spasm (HFS) is not currently available.
Objectives: To examine the reliability and validity of a short self-rating scale (HFS-7) by comparing HFS patients with healthy controls. We also evaluated the correlation of HFS-7 with the physical and mental domains of SF-36, a generic QoL scale.
Methods: Seven self-rating items (HFS-7) were administered to HFS patients and healthy controls. In addition, HFS patients answered the SF-36 questionnaire. The validity and reliability of HFS-7 were analysed and correlation between HFS-7 and SF-36 examined.
Results: A total of 178 subjects were enrolled in the study, including 85 HFS patients with mean age of 54.8 (SD 11.0) years, of whom 52 (61.2%) were women, and 93 controls with mean age of 51.4 (SD 10.0) years, of whom 59 (63.4%) were women. The test-retest intraclass correlation coefficient for the seven items was between 0.75 and 0.90 and Cronbach's coefficient of reliability for the HFS-7 scale was 0.88. Every item in HFS-7 discriminated between disease and controls (p<0.0001). The HFS-7 summary index correlated with the SF-36 summary score (Spearman's correlation r = -0.28, p = 0.009), in particular the mental health summary score (r = -0.416, p<0.0001) and the emotional domain (r = -0.466, p<0.00001).
Conclusion: HFS-7 could prove useful as a simple clinical tool to assess and monitor QoL measures in HFS patients.
References
- Arch Neurol. 2000 Aug;57(8):1224-7
- Qual Life Res. 2001;10(2):175-88
- J Neurol Neurosurg Psychiatry. 2002 Feb;72(2):241-8
- QJM. 2002 Aug;95(8):493-500
- J Health Soc Behav. 1997 Mar;38(1):21-37
- J Neurol Sci. 2004 Apr 15;219(1-2):151-5
- Biometrics. 1977 Mar;33(1):159-74
- N Engl J Med. 1991 Apr 25;324(17):1186-94
- Neurology. 2003 Jan 28;60(2):343-4
Source: PubMed