Preventing the transmission of COVID-19 and other coronaviruses in older adults aged 60 years and above living in long-term care: a rapid review
Patricia Rios, Amruta Radhakrishnan, Chantal Williams, Naveeta Ramkissoon, Ba' Pham, Gordon V Cormack, Maura R Grossman, Matthew P Muller, Sharon E Straus, Andrea C Tricco, Patricia Rios, Amruta Radhakrishnan, Chantal Williams, Naveeta Ramkissoon, Ba' Pham, Gordon V Cormack, Maura R Grossman, Matthew P Muller, Sharon E Straus, Andrea C Tricco
Abstract
Background: The objective of this review was to examine the current guidelines for infection prevention and control (IPAC) of coronavirus disease-19 (COVID-19) or other coronaviruses in adults 60 years or older living in long-term care facilities (LTCF).
Methods: EMBASE, MEDLINE, Cochrane library, pre-print servers, clinical trial registries, and relevant grey literature sources were searched until July 31, 2020, using database searching and an automated method called Continuous Active Learning® (CAL®). All search results were processed using CAL® to identify the most likely relevant citations that were then screened by a single human reviewer. Full-text screening, data abstraction, and quality appraisal were completed by a single reviewer and verified by a second.
Results: Nine clinical practice guidelines (CPGs) were included. The most common recommendation in the CPGs was establishing surveillance and monitoring systems followed by mandating the use of PPE; physically distancing or cohorting residents; environmental cleaning and disinfection; promoting hand and respiratory hygiene among residents, staff, and visitors; and providing sick leave compensation for staff.
Conclusions: Current evidence suggests robust surveillance and monitoring along with support for IPAC initiatives are key to preventing the spread of COVID-19 in LTCF. However, there are significant gaps in the current recommendations especially with regard to the movement of staff between LTCF and their role as possible transmission vectors.
Systematic review registration: PROSPERO CRD42020181993.
Keywords: COVID-19; Clinical guidelines; Knowledge synthesis; Long-term care; Older adults.
Conflict of interest statement
All authors do not have any potential (or perceived) conflicts of interest.
Figures
References
- Liu K, Chen Y, Lin R, Han K. Clinical features of COVID-19 in elderly patients: a comparison with young and middle-aged patients. J Infect. 2020;80(6):e14–ee8.
- Onder G, Rezza G, Brusaferro S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. 2020;323(18):1775–1776.
- Pollock AM, Clements L, Harding-Edgar L. Covid-19: why we need a national health and social care service. BMJ. 2020;369:m1465.
- Fisman D, Lapointe-Shaw L, Bogoch I, McCready J, Tuite A. Failing our most vulnerable: COVID-19 and long-term care facilities in Ontario. medRxiv. 2020.
- Zhang Y. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) — China, 2020. CCDC Weekly. 2020;2(8):113–112.
- Wang Y, Wang Y, Chen Y, Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures. J Med Virol. 2020;92(6):568–576.
- Tricco AC, Langlois EV, Straus SE, editors. Rapid reviews to strengthen health policy and systems: a practical guide. Geneva: World Health Organization; 2017. Licence: CC BY-NC-SA 3.0 IGO.
- Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009;339:b2535.
- Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care: a rapid review of clinical practice guidelines. Knowledge Translation Program, Unity Health Toronto. 2020. Available from: .
- McGowan J, Sampson M, Salzwedel DM, Cogo E, Foerster V, Lefebvre C. PRESS peer review of electronic search strategies: 2015 guideline statement. J Clin Epidemiol. 2016;75:40–46.
- Cormack GG, MR. Technology-assisted review in empirical medicine: Waterloo participation in CLEF eHealth 2018. Waterloo: University of Waterloo; 2018.
- Health Canada . Long-term facilities-based care Ottawa. Government of Canada: ON; 2004.
- Ontario Long Term Care Association. Long-term care services and the application process. Toronto, ON. Available from: .
- Cochrane handbook for systematic reviews of interventions (version 6.0). Cochrane. 2019. Available from: .
- Brouwers MC, Kerkvliet K, Spithoff K. The AGREE reporting checklist: a tool to improve reporting of clinical practice guidelines. BMJ. 2016;352:i1152.
- Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ. 2017;358:j4008.
- Higgins JPT, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928.
- Wells G, Shea B, O'Connell D, Peterson J, Welch V, Losos M, et al. The Newcastle–Ottawa scale (NOS) for assessing the quality of non-randomized studies in meta-analysis. 2000.
- American Geriatrics Society American Geriatrics Society policy brief: COVID-19 and nursing homes. J Am Geriatr Soc. 2020;68(5):908–911.
- ECRI. Preparation is the best protection: lessons from the 2003 SARS outbreak. Health Devices. 2020b. Available from: .
- World Health Organization . Infection prevention and control guidance for long-term care facilities in the context of COVID-19: interim guidance. Geneva: WHO; 2020.
- Kelly GGL. Guidelines, standard operating procedures and clinical practice – preventing and managing COVID-19 infections in long-term care facilities. Cape Town, SA: Sifar Samson Institute for Ageing Research; 2020.
- Health Protection Scotland . COVID-19: information and guidance for care home settings (version 1.6) Scotland, UK: National Services Scotland; 2020.
- Lester PE, Holahan T, Siskind D, Healy E. Policy recommendations regarding skilled nursing facility management of coronavirus 19 (COVID-19): lessons from New York state. J Am Med Dir Assoc. 2020;21(7):888–892.
- Centers for Disease Control and Prevention. Interim additional guidance for infection prevention and control for patients with suspected or confirmed COVID-19 in nursing homes. CDC. 2020. Available from: .
- ECRI. Protecting against infectious disease transmission during equipment maintenance: lessons from the 2003 SARS outbreak. Health Devices. 2020a. Available from: .
- Ministry of Health (MOH). COVID-19 guidance: long-term care homes. Government of Ontario. 2020. Available from: .
Source: PubMed