CT features of novel coronavirus pneumonia (COVID-19) in children

Ya-Ni Duan, Yan-Qiu Zhu, Lei-Lei Tang, Jie Qin, Ya-Ni Duan, Yan-Qiu Zhu, Lei-Lei Tang, Jie Qin

Abstract

A serious epidemic of COVID-19 broke out in Wuhan, Hubei Province, China, and spread to other Chinese cities and several countries now. As the majority of patients infected with COVID-19 had chest CT abnormality, chest CT has become an important tool for early diagnosis of COVID-19 and monitoring disease progression. There is growing evidence that children are also susceptible to COVID-19 and have atypical presentations compared with adults. This review is mainly about the differences in clinical symptom spectrum, diagnosis of COVID-19, and CT imaging findings between adults and children, while highlighting the value of radiology in prevention and control of COVID-19 in pediatric patients. KEY POINTS: • Compared with adults, pediatric patients with COVID-19 have the characteristics of lower incidence, slighter clinical symptoms, shorter course of disease, and fewer severe cases. • The chest CT characteristics of COVID-19 in pediatric patients were atypical, with more localized GGO extent, lower GGO attenuation, and relatively rare interlobular septal thickening. • Chest CT should be used with more caution in pediatric patients with COVID-19 to protect this vulnerable population from risking radiation.

Keywords: COVID-19; Pneumonia, viral; Tomography, spiral computed.

Conflict of interest statement

The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Figures

Fig. 1
Fig. 1
Chest CT imaging of coronavirus disease 2019 (COVID-19) pneumonia in children and adults. a Female, 14 years old. Chest CT showed scattered GGO in the inferior lobe of the right lung, located subpleural or extended from subpleural lesions. b Male, 10 years old. Chest CT showed consolidation with halo sign in the inferior lobe of the left lung surrounded by GGO. c Male, 1 year old. Chest CT showed diffused consolidations and GGO in both lungs, with a “white lung” appearance of the right lung. d Male, 49 years old. Chest CT showed multiple subpleural GGO in both lungs. e Male, 64 years old. Chest CT showed multiple GGO and consolidations in the right upper lobe. f Male, 34 years old. Chest CT showed diffused consolidation in the right lower lobe and left lung with fewer GGO surrounded. * Fig. 1 a to c is reproduced with permission from Xia W et al. [33]

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Source: PubMed

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