Emergence of Klebsiella pneumoniae co-producing NDM-type and OXA-181 carbapenemases
M N D Balm, M-V La, P Krishnan, R Jureen, R T P Lin, J W P Teo, M N D Balm, M-V La, P Krishnan, R Jureen, R T P Lin, J W P Teo
Abstract
The emergence of carbapenemase-producing Enterobacteriaceae is a rapidly evolving threat worldwide. Here, we report the molecular characterization of two Klebsiella pneumoniae isolates carrying both bla(OXA -181) and bla(NDM -1) or bla(NDM -5) isolated from epidemiologically unrelated patients in Singapore. The bla(OXA -181) genes were found existing in different genetic environments.
Keywords: Carbapenemases; Enterobacteriaceae; gram-negative resistance; metallo-β-lactamases; oxacillinases.
© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.
Source: PubMed