Small-bowel Capsule Endoscopic Features in Patients with Eosinophilic Gastroenteritis: Three Case Reports

Naoko Mizumoto, Yu Sasaki, Yasuhiko Abe, Makoto Yagi, Takashi Kon, Yusuke Onozato, Takayuki Sakai, Minami Ito, Matsuki Umehara, Yoshiyuki Ueno, Naoko Mizumoto, Yu Sasaki, Yasuhiko Abe, Makoto Yagi, Takashi Kon, Yusuke Onozato, Takayuki Sakai, Minami Ito, Matsuki Umehara, Yoshiyuki Ueno

Abstract

Eosinophilic gastroenteritis (EGE) is an uncommon disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes and presents with a variety of gastrointestinal manifestations. Important diagnostic evidence for EGE can be provided by endoscopy; however, the specific small-bowel capsule endoscopic (SBCE) findings remain unknown. We herein report the SBCE findings of three cases of EGE as well as those of the previous cases. The most common findings in patients with EGE were multiple erythema and erosions with surrounding redness on SBCE; these findings should be considered for the diagnostic evaluation for EGE.

Keywords: eosinophilic enteritis; erythema; small bowel erosion; video-capsule endoscopy.

Conflict of interest statement

The authors state that they have no Conflict of Interest (COI).

Figures

Figure 1.
Figure 1.
Representative images of case 1. a-c: Capsule endoscopy (PillCam SB3; Covidien, Tokyo, Japan) showing multiple small erosions with surrounding redness, c: Numerous lesions were shown in one screen in the ileum, d: Swollen villi, erosions, and linear ulceration in the terminal ileum, e: Double-balloon enteroscopy showing multiple small erosions with surrounding redness, f: Histological images (Hematoxylin and Eosin staining, ×400) of biopsy specimens from the ileum showed eosinophilic infiltration.
Figure 2.
Figure 2.
Representative images of case 2. a-c: Capsule endoscopy (PillCam SB3; Covidien) showing multiple small erosions with surrounding redness, d: Linear ulcers in the terminal ileum, e: Histological images (Hematoxylin and Eosin staining, ×400) of biopsy specimens from the ileum showed eosinophilic infiltration.
Figure 3.
Figure 3.
Representative images of case 3. a, b: Capsule endoscopy (PillCam SB3; Covidien) showing small erosions with surrounding redness, c, d: Multiple erosions in the distal ileum, e: Marked eosinophilic infiltration (Hematoxylin and Eosin staining, ×400).

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