Assessment of localisation to auditory stimulation in post-comatose states: use the patient's own name

Lijuan Cheng, Olivia Gosseries, Limei Ying, Xiaohua Hu, Dan Yu, Hongxing Gao, Minhui He, Caroline Schnakers, Steven Laureys, Haibo Di, Lijuan Cheng, Olivia Gosseries, Limei Ying, Xiaohua Hu, Dan Yu, Hongxing Gao, Minhui He, Caroline Schnakers, Steven Laureys, Haibo Di

Abstract

Background: At present, there is no consensus on how to clinically assess localisation to sound in patients recovering from coma. We here studied auditory localisation using the patient's own name as compared to a meaningless sound (i.e., ringing bell).

Methods: Eighty-six post-comatose patients diagnosed with a vegetative state/unresponsive wakefulness syndrome or a minimally conscious state were prospectively included. Localisation of auditory stimulation (i.e., head or eyes orientation toward the sound) was assessed using the patient's own name as compared to a ringing bell. Statistical analyses used binomial testing with bonferroni correction for multiple comparisons.

Results: 37 (43%) out of the 86 studied patients showed localisation to auditory stimulation. More patients (n=34, 40%) oriented the head or eyes to their own name as compared to sound (n=20, 23%; p<0.001).

Conclusions: When assessing auditory function in disorders of consciousness, using the patient's own name is here shown to be more suitable to elicit a response as compared to neutral sound.

Figures

Figure 1
Figure 1
Auditory localisation. Number of patients in vegetative/unresponsive state (VS/UWS) and minimally conscious state (MCS) showing localisation to sound (n=37) as a function of the employed stimulus (own name in black and ringing bell in white).

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