Comparison of GnRH antagonist protocol with or without oral contraceptive pill pretreatment and GnRH agonist low-dose long protocol in low responders undergoing IVF/intracytoplasmic sperm injection
Chung-Hoon Kim, Gyun-Ho Jeon, Yong-Pil Cheon, Ilkyung Jeon, Sung-Hoon Kim, Hee-Dong Chae, Byung-Moon Kang, Chung-Hoon Kim, Gyun-Ho Jeon, Yong-Pil Cheon, Ilkyung Jeon, Sung-Hoon Kim, Hee-Dong Chae, Byung-Moon Kang
Abstract
This prospective randomized study was performed to compare the efficacy of GnRH antagonist multiple-dose protocol (MDP) with or without oral contraceptive pill (OCP) pretreatment and GnRH agonist low-dose long protocol (LP) in 82 patients undergoing IVF/intracytoplasmic sperm injection (ICSI). GnRH antagonist MDP with OCP pretreatment was at least as effective as GnRH agonist low-dose LP in low responders, and can benefit the low responders by reducing the amount of FSH and the number of days of stimulation required for follicular maturation.
Source: PubMed