Perceived function and physical performance are associated with pain and fatigue in women with fibromyalgia

Dana L Dailey, Laura A Frey Law, Carol G T Vance, Barbara A Rakel, Ericka N Merriwether, Leon Darghosian, Meenakshi Golchha, Katharine M Geasland, Rebecca Spitz, Leslie J Crofford, Kathleen A Sluka, Dana L Dailey, Laura A Frey Law, Carol G T Vance, Barbara A Rakel, Ericka N Merriwether, Leon Darghosian, Meenakshi Golchha, Katharine M Geasland, Rebecca Spitz, Leslie J Crofford, Kathleen A Sluka

Abstract

Background: Fibromyalgia is a condition characterized by chronic widespread muscle pain and fatigue and associated with significant impairment in perceived function and reduced physical performance. The purpose of this study was to determine the degree to which pain and fatigue are associated with perceived function and physical performance in women with fibromyalgia.

Methods: Hierarchical linear regression determined the contribution of pain and fatigue (Numeric Rating Scale (NRS) for resting, movement and combined) to perceived function (Fibromyalgia Impact Questionnaire Revised - Function Subscale, FIQR-Function), Multidimensional Assessment of Fatigue - Activities of Daily Living (MAF-ADL) and SF-36 Physical Function Subscale (SF-36-PF) and physical performance (6-Minute Walk Test, 6MWT and Five Time Sit To Stand, 5TSTS) while controlling for age, body mass index, pain catastrophizing, fear of movement, anxiety, and depression in women with fibromyalgia (N = 94).

Results: For perceived function, movement pain and movement fatigue together better predicted FIQR-function (adjusted R(2) = 0.42, p ≤ 0.001); MAF-ADL (adjusted R(2) = 0.41, p ≤ 0.001); and SF-36-PF function (adjusted R(2) = 0.34, p ≤ 0.001). For physical performance measures, movement pain and fatigue together predicted 6MWT distance (adjusted R(2) = 0.42, p ≤ 0.001) and movement fatigue alone predicted performance time on the 5TSTS (adjusted R(2) = 0.20, p ≤ 0.001).

Conclusions: Pain and fatigue are significantly associated with and explain more than one-third of the variance in perceived function and physical performance in women with fibromyalgia.

Trial registration: NIH Clinicaltrials.gov

Registration: NCT01888640 . Registered 13 June 2013.

References

    1. Anderson RJ, McCrae CS, Staud R, Berry RB, Robinson ME. Predictors of clinical pain in fibromyalgia: examining the role of sleep. J Pain. 2012;13:350–8. doi: 10.1016/j.jpain.2011.12.009.
    1. Arnold LM, Crofford LJ, Mease PJ, Burgess SM, Palmer SC, Abetz L, et al. Patient perspectives on the impact of fibromyalgia. Patient Educ Couns. 2008;73:114–20. doi: 10.1016/j.pec.2008.06.005.
    1. Bohannon RW. Test-retest reliability of the five-repetition sit-to-stand test: a systematic review of the literature involving adults. J Strength Cond Res. 2011;25:3205–7. doi: 10.1519/JSC.0b013e318234e59f.
    1. Bennett RM, Russell J, Cappelleri JC, Bushmakin AG, Zlateva G, Sadosky A. Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis. BMC Musculoskelet Disord. 2010;11:134. doi: 10.1186/1471-2474-11-134.
    1. Schaefer KM. Health patterns of women with fibromyalgia. J Adv Nurs. 1997;26:565–71. doi: 10.1046/j.1365-2648.1997.t01-17-00999.x.
    1. Bennett RM, Jones J, Turk DC, Russell IJ, Matallana L. An internet survey of 2,596 people with fibromyalgia. BMC Musculoskelet Disord. 2007;8:27. doi: 10.1186/1471-2474-8-27.
    1. Okifuji A, Bradshaw DH, Donaldson GW, Turk DC. Sequential analyses of daily symptoms in women with fibromyalgia syndrome. J Pain. 2011;12:84–93. doi: 10.1016/j.jpain.2010.05.003.
    1. Henriksson C, Gundmark I, Bengtsson A, Ek AC. Living with fibromyalgia. Consequences for everyday life. Clin J Pain. 1992;8:138–44. doi: 10.1097/00002508-199206000-00012.
    1. Silverman S, Sadosky A, Evans C, Yeh Y, Alvir JM, Zlateva G. Toward characterization and definition of fibromyalgia severity. BMC Musculoskelet Disord. 2010;11:66. doi: 10.1186/1471-2474-11-66.
    1. Goes SM, Leite N, Shay BL, Homann D, Stefanello JM, Rodacki AL. Functional capacity, muscle strength and falls in women with fibromyalgia. Clin Biomech (Bristol, Avon) 2012;27:578–83. doi: 10.1016/j.clinbiomech.2011.12.009.
    1. Wolfe F. Fibromyalgia. Rheum Dis Clin North Am. 1990;16:681–98.
    1. Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res (Hoboken) 2010;62:600–10. doi: 10.1002/acr.20140.
    1. Wolfe F, Hawley DJ, Wilson K. The prevalence and meaning of fatigue in rheumatic disease. J Rheumatol. 1996;23:1407–17.
    1. Ge HY, Nie H, Graven-Nielsen T, Danneskiold-Samsoe B, Arendt-Nielsen L. Descending pain modulation and its interaction with peripheral sensitization following sustained isometric muscle contraction in fibromyalgia. Eur J Pain. 2012;16:196–203. doi: 10.1016/j.ejpain.2011.06.008.
    1. Fisk JD, Ritvo PG, Ross L, Haase DA, Marrie TJ, Schlech WF. Measuring the functional impact of fatigue: initial validation of the fatigue impact scale. Clin Infect Dis. 1994;18(Suppl 1):S79–83. doi: 10.1093/clinids/18.Supplement_1.S79.
    1. Bennett R. The Fibromyalgia Impact Questionnaire (FIQ): a review of its development, current version, operating characteristics and uses. Clin Exp Rheumatol. 2005;23(5 Suppl 39):S154–62.
    1. Bennett RM, Bushmakin AG, Cappelleri JC, Zlateva G, Sadosky AB. Minimal clinically important difference in the fibromyalgia impact questionnaire. J Rheumatol. 2009;36:1304–11. doi: 10.3899/jrheum.081090.
    1. Bennett RM, Friend R, Jones KD, Ward R, Han BK, Ross RL. The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties. Arthritis Res Ther. 2009;11:R120. doi: 10.1186/ar2783.
    1. Centers for Disease Control and Prevention. Fibromyalgia Available at: . Date accessed: June 2013.
    1. Carbonell-Baeza A, Aparicio VA, Sjostrom M, Ruiz JR, Delgado-Fernandez M. Pain and functional capacity in female fibromyalgia patients. Pain Med. 2011;12:1667–75. doi: 10.1111/j.1526-4637.2011.01239.x.
    1. Culos-Reed SN, Brawley LR. Fibromyalgia, physical activity, and daily functioning: the importance of efficacy and health-related quality of life. Arthritis Care Res. 2000;13:343–51. doi: 10.1002/1529-0131(200012)13:6<343::AID-ART3>;2-P.
    1. Bohannon RW, Bubela D, Magasi S, McCreath H, Wang YC, Reuben D, et al. Comparison of walking performance over the first 2 minutes and the full 6 minutes of the Six-Minute Walk Test. BMC Res Notes. 2014;7:269. doi: 10.1186/1756-0500-7-269.
    1. Cardoso Fde S, Curtolo M, Natour J, Lombardi Junior I. Assessment of quality of life, muscle strength and functional capacity in women with fibromyalgia. Rev Bras Reumatol. 2011;51:338–43.
    1. Homann D, Stefanello JM, Goes SM, Leite N. Impaired functional capacity and exacerbation of pain and exertion during the 6-minute walk test in women with fibromyalgia. Rev Bras Fisioter. 2011;15:474–80. doi: 10.1590/S1413-35552011000600008.
    1. Dailey DL, Keffala VJ, Sluka KA. Cognitive and physical fatigue tasks enhance pain, cognitive fatigue and physical fatigue in people with fibromyalgia. Arthritis Care Res (Hoboken) 2015;67:288–96. doi: 10.1002/acr.22417.
    1. Fontaine KR, Conn L, Clauw DJ. Effects of lifestyle physical activity on perceived symptoms and physical function in adults with fibromyalgia: results of a randomized trial. Arthritis Res Ther. 2010;12:R55. doi: 10.1186/ar2967.
    1. Kadetoff D, Kosek E. The effects of static muscular contraction on blood pressure, heart rate, pain ratings and pressure pain thresholds in healthy individuals and patients with fibromyalgia. Eur J Pain. 2007;11:39–47. doi: 10.1016/j.ejpain.2005.12.013.
    1. Staud R. Peripheral and central mechanisms of fatigue in inflammatory and noninflammatory rheumatic diseases. Curr Rheumatol Rep. 2012;14:539–48. doi: 10.1007/s11926-012-0277-z.
    1. Noehren B, Dailey DL, Rakel BA, Vance CG, Zimmerman MB, Crofford LJ, et al. Effect of transcutaneous electrical nerve stimulation on pain, function, and quality of life in fibromyalgia: a double-blind randomized clinical trial. Phys Ther. 2015;95:129–40. doi: 10.2522/ptj.20140218.
    1. Jensen MP, McFarland CA. Increasing the reliability and validity of pain intensity measurement in chronic pain patients. Pain. 1993;55:195–203. doi: 10.1016/0304-3959(93)90148-I.
    1. Kahl C, Cleland J. Visual analogue scale, numeric rating scale and the McGill Pain Questionnaire: an overview of psychometric properties. Phys Ther. 2005;10:123–8. doi: 10.1179/108331905X55776.
    1. Lentz TA, Barabas JA, Day T, Bishop MD, George SZ. The relationship of pain intensity, physical impairment, and pain-related fear to function in patients with shoulder pathology. J Orthop Sports Phys Ther. 2009;39:270–7. doi: 10.2519/jospt.2009.2879.
    1. McHorney CA, Ware JE, Jr, Lu JF, Sherbourne CD. The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care. 1994;32:40–66. doi: 10.1097/00005650-199401000-00004.
    1. Steffen TM, Hacker TA, Mollinger L. Age- and gender-related test performance in community-dwelling elderly people: Six-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and gait speeds. Phys Ther. 2002;82:128–37.
    1. Novy DM, Simmonds MJ, Lee CE. Physical performance tasks: what are the underlying constructs? Arch Phys Med Rehabil. 2002;83:44–7. doi: 10.1053/apmr.2002.27397.
    1. Simmonds MJ, Olson SL, Jones S, Hussein T, Lee CE, Novy D, et al. Psychometric characteristics and clinical usefulness of physical performance tests in patients with low back pain. Spine (Phila Pa 1976) 1998;23:2412–21. doi: 10.1097/00007632-199811150-00011.
    1. Thieme K, Turk DC, Gracely RH, Maixner W, Flor H. The relationship among psychological and psychophysiological characteristics of fibromyalgia patients. J Pain. 2015;16:186–96. doi: 10.1016/j.jpain.2014.11.009.
    1. Osman A, Barrios FX, Gutierrez PM, Kopper BA, Merrifield T, Grittmann L. The Pain Catastrophizing Scale: further psychometric evaluation with adult samples. J Behav Med. 2000;23:351–65. doi: 10.1023/A:1005548801037.
    1. Burwinkle T, Robinson JP, Turk DC. Fear of movement: factor structure of the tampa scale of kinesiophobia in patients with fibromyalgia syndrome. J Pain. 2005;6:384–91. doi: 10.1016/j.jpain.2005.01.355.
    1. Roelofs J, Goubert L, Peters ML, Vlaeyen JW, Crombez G. The Tampa Scale for Kinesiophobia: further examination of psychometric properties in patients with chronic low back pain and fibromyalgia. Eur J Pain. 2004;8:495–502. doi: 10.1016/j.ejpain.2003.11.016.
    1. Patient-Reported Outcomes Measurement Information System (PROMIS) Available at: .Date Accessed: June 2011.
    1. Kroenke K, Yu Z, Wu J, Kean J, Monahan PO. Operating characteristics of PROMIS four-item depression and anxiety scales in\par primary care patients with chronic pain. Pain Med. 2014;15:1892–901. doi: 10.1111/pme.12537.
    1. Van Liew C, Brown KC, Cronan TA, Bigatti SM, Kothari DJ. Predictors of pain and functioning over time in fibromyalgia syndrome: an autoregressive path analysis. Arthritis Care Res (Hoboken) 2013;65:251–6. doi: 10.1002/acr.21792.
    1. Staud R. Predictors of clinical pain intensity in patients with fibromyalgia syndrome. Curr Rheumatol Rep. 2004;6:281–6. doi: 10.1007/s11926-004-0036-x.
    1. Rodero B, Casanueva B, Garcia-Campayo J, Roca M, Magallon R, del Hoyo YL. Stages of chronicity in fibromyalgia and pain catastrophising: a cross-sectional study. BMC Musculoskelet Disord. 2010;11:251. doi: 10.1186/1471-2474-11-251.
    1. Hassett AL, Cone JD, Patella SJ, Sigal LH. The role of catastrophizing in the pain and depression of women with fibromyalgia syndrome. Arthritis Rheum. 2000;43:2493–500. doi: 10.1002/1529-0131(200011)43:11<2493::AID-ANR17>;2-W.
    1. Sanchez AI, Martinez MP, Miro E, Medina A. Predictors of the pain perception and self-efficacy for pain control in patients with fibromyalgia. Span J Psychol. 2011;14:366–73. doi: 10.5209/rev_SJOP.2011.v14.n1.33.
    1. Schaefer C, Chandran A, Hufstader M, Baik R, McNett M, Goldenberg D, et al. The comparative burden of mild, moderate and severe fibromyalgia: results from a cross-sectional survey in the United States. Health Qual Life Outcomes. 2011;9:71. doi: 10.1186/1477-7525-9-71.
    1. de Bruijn ST, van Wijck AJ, Geenen R, Snijders TJ, van der Meulen WJ, Jacobs JW, et al. Relevance of physical fitness levels and exercise-related beliefs for self-reported and experimental pain in fibromyalgia: an explorative study. J Clin Rheumatol. 2011;17:295–301. doi: 10.1097/RHU.0b013e31822c5196.
    1. Breda CA, Rodacki AL, Leite N, Homann D, Goes SM, Stefanello JM. Physical activity level and physical performance in the 6-minute walk test in women with fibromyalgia. Rev Bras Rheumatol. 2013;53:276–81. doi: 10.1590/S0482-50042013000300005.
    1. Lindemann U, Claus H, Stuber M, Augat P, Muche R, Nikolaus T, et al. Measuring power during the sit-to-stand transfer. Eur J Appl Physiol. 2003;89:466–70. doi: 10.1007/s00421-003-0837-z.
    1. Denison E, Asenlof P, Lindberg P. Self-efficacy, fear avoidance, and pain intensity as predictors of disability in subacute and chronic musculoskeletal pain patients in primary health care. Pain. 2004;111:245–52. doi: 10.1016/j.pain.2004.07.001.
    1. Saavedra-Hernandez M, Castro-Sanchez AM, Cuesta-Vargas AI, Cleland JA, Fernandez-de-las-Penas C, Arroyo-Morales M. The contribution of previous episodes of pain, pain intensity, physical impairment, and pain-related fear to disability in patients with chronic mechanical neck pain. Am J Phys Med Rehabil. 2012;91:1070–6. doi: 10.1097/PHM.0b013e31827449a5.
    1. Staud R, Price DD, Robinson ME, Vierck CJ., Jr Body pain area and pain-related negative affect predict clinical pain intensity in patients with fibromyalgia. J Pain. 2004;5:338–43. doi: 10.1016/j.jpain.2004.05.007.
    1. Przekop P, Haviland MG, Morton KR, Oda K, Fraser GE. Correlates of perceived pain-related restrictions among women with fibromyalgia. Pain Med. 2010;11:1698–706. doi: 10.1111/j.1526-4637.2010.00988.x.
    1. Nicassio PM, Moxham EG, Schuman CE, Gevirtz RN. The contribution of pain, reported sleep quality, and depressive symptoms to fatigue in fibromyalgia. Pain. 2002;100:271–9. doi: 10.1016/S0304-3959(02)00300-7.
    1. Rutledge DN, Jones K, Jones CJ. Predicting high physical function in people with fibromyalgia. J Nurs Scholarsh. 2007;39:319–24. doi: 10.1111/j.1547-5069.2007.00187.x.

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