Health benefits of probiotics: a review

Maria Kechagia, Dimitrios Basoulis, Stavroula Konstantopoulou, Dimitra Dimitriadi, Konstantina Gyftopoulou, Nikoletta Skarmoutsou, Eleni Maria Fakiri, Maria Kechagia, Dimitrios Basoulis, Stavroula Konstantopoulou, Dimitra Dimitriadi, Konstantina Gyftopoulou, Nikoletta Skarmoutsou, Eleni Maria Fakiri

Abstract

Probiotic bacteria have become increasingly popular during the last two decades as a result of the continuously expanding scientific evidence pointing to their beneficial effects on human health. As a result they have been applied as various products with the food industry having been very active in studying and promoting them. Within this market the probiotics have been incorporated in various products, mainly fermented dairy foods. In light of this ongoing trend and despite the strong scientific evidence associating these microorganisms to various health benefits, further research is needed in order to establish them and evaluate their safety as well as their nutritional aspects. The purpose of this paper is to review the current documentation on the concept and the possible beneficial properties of probiotic bacteria in the literature, focusing on those available in food.

References

    1. Ziemer CJ, Gibson GR. An overview of probiotics, prebiotics and synbiotics in the functional food concept: perspectives and future strategies. International Dairy Journal. 1998;8(5-6):473–479.
    1. Granato D, Branco GF, Nazzaro F, Cruz AG, Faria JA. Functional foods and nondairy probiotic food development: trends, concepts, and products. Comprehensive Reviews in Food Science and Food Safety. 2010;9(3):292–302.
    1. Toma MM, Pokrotnieks J. Probiotics as functional food: microbiological and medical aspects. Acta Universitatis. 2006;710:117–129.
    1. Salminen SJ, Gueimonde M, Isolauri E. Probiotics that modify disease risk. Journal of Nutrition. 2005;135(5):1294–1298.
    1. Fuller R. Probiotics a Critical Review. Wymondham, UK: Horizon Scientific; 1999. Probiotics for farm animals; pp. 15–22.
    1. Fuller R. Probiotics in man and animals. Journal of Applied Bacteriology. 1989;66(5):365–378.
    1. FAO/WHO. Report on Joint FAO/WHO Expert Consultation on Evaluation of Health and Nutritional Properties of Probiotics in Food Including Powder Milk with Live Lactic Acid Bacteria. 2001.
    1. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. Journal of Nutrition. 1995;125(6):1401–1412.
    1. Berg RD. Probiotics, prebiotics or "conbiotics"? Trends in Microbiology. 1998;6(3):89–92.
    1. Holzapfel WH, Haberer P, Geisen R, Björkroth J, Schillinger U. Taxonomy and important features of probiotic microorganisms in food and nutrition. American Journal of Clinical Nutrition. 2001;73(2):365S–373S.
    1. Felis GE, Dellaglio F. Taxonomy of lactobacilli and bifidobacteria. Current Issues in Intestinal Microbiology. 2007;8:44–61.
    1. Mercenier A, Lenoir-Wijnkoop I, Sanders ME. Physiological and functional properties of probiotics. International Dairy Federation. 2008;429:2–6.
    1. Joint FAO/WHO Working Group Report on Drafting Guidelines for the Evaluation of Probiotics in Food. Ontario, Canada: 2002. .
    1. Saarela M, Mogensen G, Fondén R, Mättö J, Mattila-Sandholm T. Probiotic bacteria: safety, functional and technological properties. Journal of Biotechnology. 2000;84(3):197–215.
    1. Sanders ME. Probiotics: definition, sources, selection, and uses. Clinical Infectious Diseases. 2008;46(2):S58–S61.
    1. Galdeano CM, Perdigón G. Role of viability of probiotic strains in their persistence in the gut and in mucosal immune stimulation. Journal of Applied Microbiology. 2004;97(4):673–681.
    1. Kosin B, Rakshit SK. Criteria for production of probiotics. Food Technology and Biotechnology. 2006;44(3):371–379.
    1. Lahtinen SJ. Probiotic viability—does it matter? Microbial Ecology in Health and Disease. 2012;23:10–14.
    1. Salminen S, Ouwehand A, Benno Y, Lee YK. Probiotics: how should they be defined? Trends in Food Science and Technology. 1999;10(3):107–110.
    1. Guarner F, Malagelada JR. Gut flora in health and disease. The Lancet. 2003;361(9356):512–519.
    1. McNaught CE, MacFie J. Probiotics in clinical practice: a critical review of the evidence. Nutrition Research. 2001;21(1-2):343–353.
    1. Isolauri E, Sütas Y, Kankaanpää P, Arvilommi H, Salminen S. Probiotics: effects on immunity. American Journal of Clinical Nutrition. 2001;73(2):444S–450S.
    1. Stanton C, Gardiner G, Meehan H, et al. Market potential for probiotics. American Journal of Clinical Nutrition. 2001;73(2):476S–483S.
    1. Modest Growth for Global Probiotic Market, .
    1. Ewe JA, Wan Nadiah WA, Liong MT. Viability and growth characteristics of Lactobacillus in soymilk supplemented with B-vitamins. International Journal of Food Sciences and Nutrition. 2010;61(1):87–107.
    1. Sheehan VM, Ross P, Fitzgerald GF. Assessing the acid tolerance and the technological robustness of probiotic cultures for fortification in fruit juices. Innovative Food Science and Emerging Technologies. 2007;8(2):279–284.
    1. Medina IM, Jordano R. Survival of constitutive microflora in commercially fermented milk containing bifidobacteria during refrigerated storage. Journal of Food Protection. 1994;56:731–733.
    1. Gardiner G, Ross RP, Collins JK, Fitzgerald G, Stanton C. Development of a probiotic Cheddar cheese containing human-derived Lactobacillus paracasei strains. Applied and Environmental Microbiology. 1998;64(6):2192–2199.
    1. Kehagias C, Koulouris S, Arkoudelos J, Samona A. Viability and biochemical activity of bifidobacteria in association with yoghurt starter cultures in bifidus milk and bio-yoghurt during storage at 4°C. Egyptian Journal of Dairy Science. 2006;34(2):151–158.
    1. Pszczola DE. What makes a winning ingredient? Food Technology. 2012;66(8):58–85.
    1. O'Sullivan DJ. Exploring the potential to utilize lantibiotic-producing bifidobacteria to create dairy ingredients with increased broadspectrum antimicrobial functionalities yields encouraging results. Food Technology. 2012;66(6):45–50.
    1. McFarland LV. Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. American Journal of Gastroenterology. 2006;101(4):812–822.
    1. Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE. Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. The Lancet Infectious Diseases. 2006;6(6):374–382.
    1. Hempel S, Newberry SJ, Maher AR, et al. Probiotics for the prevention and treatment of antibiotic-associated diarrhea a systematic review and meta-analysis. The Journal of the American Medical Association. 2012;307(18):1959–1969.
    1. Salminen S, Bouley C, Boutron-Ruault MC, et al. Functional food science and gastrointestinal physiology and function. British Journal of Nutrition. 1998;80(1):S147–S171.
    1. Shah NP. Functional cultures and health benefits. International Dairy Journal. 2007;17(11):1262–1277.
    1. Szajewska H, Mrukowicz JZ. Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebo-controlled trials. Journal of Pediatric Gastroenterology and Nutrition. 2001;33(4):S17–S25.
    1. Isolauri E, Kirjavainen PV, Salminen S. Probiotics: a role in the treatment of intestinal infection and inflammation? Gut. 2002;50(3):iii54–iii59.
    1. Huang JS, Bousvaros A, Lee JW, Diaz A, Davidson EJ. Efficacy of probiotic use in acute diarrhea in children: a meta-analysis. Digestive Diseases and Sciences. 2002;47(11):2625–2634.
    1. Pedone CA, Bernabeu AO, Postaire ER, Bouley CF, Reinert P. The effect of supplementation with milk fermented by Lactobacillus casei (strain DN-114 001) on acute diarrhoea in children attending day care centres. International Journal of Clinical Practice. 1999;53(3):179–184.
    1. McFarland LV. Meta-analysis of probiotics for the prevention of traveler’s diarrhea. Travel Medicine and Infectious Disease. 2007;5(2):97–105.
    1. Marteau P, Seksik P, Jian R. Probiotics and intestinal health effects: a clinical perspective. British Journal of Nutrition. 2002;88(1):S51–S57.
    1. Hilton E, Kolakowski P, Singer C, Smith M. Efficacy of Lactobacillus GG as a diarrheal preventive in travelers. Journal of Travel Medicine. 1997;4(1):41–43.
    1. Moslehi-Jenabian S, Nielsen DS, Jespersen L. Application of molecular biology and genomics of probiotics for enteric cytoprotection. In: Malago JJ, Koninkx JFJG, Marinsek-Logar R, editors. Probiotic Bacteria and Enteric Infections. Cytoprotection By Probiotic Bacteria. New York, NY, USA: Springer; 2011. pp. 133–153.
    1. de Vrese M, Stegelmann A, Richter B, Fenselau S, Laue C, Schrezenmeir J. Probiotics-compensation for lactase insufficiency. American Journal of Clinical Nutrition. 2001;73(2):421S–429S.
    1. Levri KM, Ketvertis K, Deramo M, Merenstein JH, D’Amico F. Do probiotics reduce adult lactose intolerance? A systematic review. Journal of Family Practice. 2005;54(7):613–620.
    1. Salminen S, Ouwehand AC, Isolari E. Clinical applications of probiotic bacteria. International Dairy Journal. 1998;8:563–572.
    1. Kalliomäki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. Journal of Allergy and Clinical Immunology. 2001;107(1):129–134.
    1. Ouwehand AC, Isolauri E, He F, Hashimoto H, Benno Y, Salminen S. Differences in Bifidobacterium flora composition in allergic and healthy infants. Journal of Allergy and Clinical Immunology. 2001;108(1):144–145.
    1. Isolauri E, Arvola T, Sutas Y, Moilanen E, Salminen S. Probiotics in the management of atopic eczema. Clinical and Experimental Allergy. 2000;30(11):1604–1610.
    1. Wheeler JG, Shema SJ, Bogle ML, et al. Immune and clinical impact of Lactobacillus acidophilus on asthma. Annals of Allergy, Asthma and Immunology. 1997;79(3):229–233.
    1. Isolauri E, Majamaa H, Arvola T, Rantala I, Virtanen E, Arvilommi H. Lactobacillus casei strain GG reverses increased intestinal permeability induced by cow milk in suckling rats. Gastroenterology. 1993;105(6):1643–1650.
    1. Pelto L, Salminen SJ, Isolauri E. Lactobacillus Gg modulates milk-induced immune inflammatory response in milk-hypersensitive adults. Nutrition Today. 1996;31(6):45S–46S.
    1. Trapp CL, Chang CC, Halpern GM, Keen CL, Gershwin ME. The influence of chronic yogurt consumption on populations of young and elderly adults. International Journal of Immunotherapy. 1993;9(1):53–64.
    1. Hirayama K, Rafter J. The role of lactic acid bacteria in colon cancer prevention: mechanistic considerations. Antonie van Leeuwenhoek. 1999;76(1–4):391–394.
    1. Kumar M, Kumar A, Nagpal R, et al. Cancer-preventing attributes of probiotics: an update. International Journal of Food Sciences and Nutrition. 2010;61(5):473–496.
    1. Sanders ME. Probiotics. Food Technology. 1999;53:67–77.
    1. Falagas ME, Betsi GI, Athanasiou S. Probiotics for the treatment of women with bacterial vaginosis. Clinical Microbiology and Infection. 2007;13(7):657–664.
    1. Masco L, Ventura M, Zink R, Huys G, Swings J. Polyphasic taxonomic analysis of Bifidobacterium animalis and Bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of Bifidobacterium animalis as Bifidobacterium animalis subsp. animalis subsp. nov and Bifidobacterium lactis as Bifidobacterium animalis subsp. lactis subsp. nov. International Journal of Systematic and Evolutionary Microbiology. 2004;54(4):1137–1143.

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