End-of-life management protocol offered within emergency room (EMPOWER): study protocol for a multicentre study

Rakhee Yash Pal, Win Sen Kuan, Ling Tiah, Ranjeev Kumar, Yoko Kin Yoke Wong, Luming Shi, Charles Qishi Zheng, Jingping Lin, Sufang Liang, Uma Chandra Segara, Woon Chai Yong, Noreen Guek Cheng Chan, Mui Teng Chua, Irwani Ibrahim, Rakhee Yash Pal, Win Sen Kuan, Ling Tiah, Ranjeev Kumar, Yoko Kin Yoke Wong, Luming Shi, Charles Qishi Zheng, Jingping Lin, Sufang Liang, Uma Chandra Segara, Woon Chai Yong, Noreen Guek Cheng Chan, Mui Teng Chua, Irwani Ibrahim

Abstract

Background: Patients at their end-of-life (EOL) phase frequently visit the emergency department (ED) due to their symptoms, yet the environment and physicians in ED are not traditionally equipped or trained to provide palliative care. This multicentre study aims to measure the current quality of EOL care in ED to identify gaps, formulate improvements and implement the improved EOL care protocol. We shall also evaluate healthcare resource utilisation and its associated costs.

Methods and analysis: This study employs a quasiexperimental interrupted time series design using both qualitative and quantitative methods, involving the EDs of three tertiary hospitals in Singapore, over a period of 3 years. There are five phases in this study: (1) retrospective chart reviews of patients who died within 5 days of ED attendance; (2) pilot phase to validate the CODE questionnaire in the local context; (3) preimplementation phase; (4) focus group discussions (FGDs); and (5) postimplementation phase. In the prospective cohort, patients who are actively dying or have high likelihood of mortality this admission, and whose goal of care is palliation, will be eligible for inclusion. At least 140 patients will be recruited for each preimplementation and postimplementation phase. There will be face-to-face interviews with patients' family members, review of medical records and self-administered staff survey to evaluate existing knowledge and confidence. The FGDs will involve hospital and community healthcare providers. Data obtained from the retrospective cohort, preimplementation phase and FGDs will be used to guide prospective improvement and protocol changes. Patient, family and staff relevant outcomes from these changes will be measured using time series regression.

Ethics and dissemination: The study protocol has been reviewed and ethics approval obtained from the National Healthcare Group Domain Specific Review Board, Singapore. The results from this study will be actively disseminated through manuscript publications and conference presentations.

Trial registration number: NCT03906747.

Keywords: cost effectiveness; emergency medical services; palliative care; terminally ill.

Conflict of interest statement

Competing interests: The authors declare that they have no competing interests. This study is funded by a major government funding body (National Medical Research Council, Ministry of Health, Singapore), and there is no funding or assistance from any commercial organisation.

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Figures

Figure 1
Figure 1
EOL care workflow in the emergency departments of National University Hospital (NUH), Changi General Hospital (CGH) and Khoo Teck Puat Hospital (KTPH).

References

    1. Field MJ, Cassel CK. Approaching death: improving care at the end of life. N Engl J Med 1998;339:274–5.
    1. Stjernswärd J, Foley KM, Ferris FD. The public health strategy for palliative care. J Pain Symptom Manage 2007;33:486–93. 10.1016/j.jpainsymman.2007.02.016
    1. Tang ST. When death is imminent: where terminally ill patients with cancer prefer to die and why. Cancer Nurs 2003;26:245–51. 10.1097/00002820-200306000-00012
    1. Gloss K. End of life care in emergency departments: a review of the literature. Emerg Nurse 2017;25:29–38. 10.7748/en.2017.e1707
    1. Smith AK, McCarthy E, Weber E, et al. . Half of older Americans seen in emergency department in last month of life; most admitted to Hospital, and many die there. Health Aff 2012;31:1277–85. 10.1377/hlthaff.2011.0922
    1. Krikorian A, Limonero JT, Maté J. Suffering and distress at the end-of-life. Psychooncology 2012;21:799–808. 10.1002/pon.2087
    1. Beckstrand RL, Wood RD, Callister LC, et al. . Emergency nurses' suggestions for improving end-of-life care obstacles. J Emerg Nurs 2012;38:e7–14. 10.1016/j.jen.2012.03.008
    1. Kistler EA, Sean Morrison R, Richardson LD, et al. . Emergency department-triggered palliative care in advanced cancer: proof of concept. Acad Emerg Med 2015;22:237–9. 10.1111/acem.12573
    1. Lien centre for palliative care, Duke-NUS graduate medical school. Report on the National strategy for palliative care, 2011. Available: [Accessed 13 June 2017].
    1. Chan GK. End-Of-Life models and emergency department care. Acad Emerg Med 2004;11:79–86. 10.1197/j.aem.2003.07.019
    1. Selman L, Robinson V, Klass L, et al. . Improving confidence and competence of healthcare professionals in end-of-life care: an evaluation of the 'Transforming End of Life Care' course at an acute hospital trust. BMJ Support Palliat Care 2016;6:231–6. 10.1136/bmjspcare-2015-000879
    1. Luhrs CA, Penrod JD. End-Of-Life care pathways. Curr Opin Support Palliat Care 2007;1:198–201. 10.1097/SPC.0b013e3282f1aae6
    1. Weng T-C, Yang Y-C, Chen P-J, et al. . Implementing a novel model for hospice and palliative care in the emergency department. Medicine 2017;96:e6943 10.1097/MD.0000000000006943
    1. Aldridge MD, Kelley AS. The myth regarding the high cost of end-of-life care. Am J Public Health 2015;105:2411–5. 10.2105/AJPH.2015.302889
    1. Threapleton DE, Chung RY, Wong SYS, et al. . Care toward the end of life in older populations and its implementation facilitators and barriers: a scoping review. J Am Med Dir Assoc 2017;18:1000–9. 10.1016/j.jamda.2017.04.010
    1. Poon CH. Public healthcare sector to be reorganised into 3 integrated clusters, new polyclinic group to be formed. The Straits Times, 2017. Available: [Accessed 16 October 2019].
    1. Chor WPD, Wong SYP, Ikbal MFBM, et al. . Initiating end-of-life care at the emergency department: an observational study. Am J Hosp Palliat Care 2019;36:941–6. 10.1177/1049909119836931
    1. Mayland CR, Lees C, Germain A, et al. . Caring for those who die at home: the use and validation of 'Care Of the Dying Evaluation' (CODE) with bereaved relatives. BMJ Support Palliat Care 2014;4:167–74. 10.1136/bmjspcare-2013-000596
    1. Karnofsky D, Burchenal J. The clinical evaluation of chemotherapeutic agents in cancer.. Eval Chemother agents 1949:191–205.

Source: PubMed

3
구독하다