TNM staging of midgut and hindgut (neuro) endocrine tumors: a consensus proposal including a grading system

G Rindi, G Klöppel, A Couvelard, P Komminoth, M Körner, J M Lopes, A-M McNicol, O Nilsson, A Perren, A Scarpa, J-Y Scoazec, B Wiedenmann, G Rindi, G Klöppel, A Couvelard, P Komminoth, M Körner, J M Lopes, A-M McNicol, O Nilsson, A Perren, A Scarpa, J-Y Scoazec, B Wiedenmann

Abstract

Criteria for the staging and grading of neuroendocrine tumors (NETs) of midgut and hindgut origin were established at the second Consensus Conference in Frascati (Rome) organized by the European Neuroendocrine Tumor Society (ENETS). The proposed tumor-node-metastasis (TNM) classifications are based on the recently published ENETS Guidelines for the Diagnosis and Treatment of gastroenteropancreatic NETs and follow our previous proposal for foregut tumors. The new TNM classifications for NETs of the ileum, appendix, colon, and rectum, and the grading system were designed, discussed, and consensually approved by all conference participants. These proposals need to be validated and are meant to help clinicians in the stratification, treatment and follow-up of patients.

References

    1. Neuroendocrinology. 2004;80(6):394-424
    1. Int J Cancer. 2001 Nov 1;94(3):444-8
    1. Virchows Arch. 1995;425(6):547-60
    1. Virchows Arch. 2006 Oct;449(4):395-401
    1. Digestion. 2000;62 Suppl 1:19-26
    1. Hum Pathol. 2002 Nov;33(11):1126-32
    1. Ann N Y Acad Sci. 2004 Apr;1014:13-27
    1. Cancer. 2001 Oct 15;92(8):2204-10
    1. Cancer Res. 2001 Jan 1;61(1):285-92
    1. J Clin Oncol. 1998 Mar;16(3):1040-53
    1. Acta Oncol. 2004;43(7):626-36
    1. Gut. 2005 Jun;54 Suppl 4:iv1-16
    1. Am J Clin Pathol. 2003 Nov;120(5):706-11
    1. Anticancer Res. 2005 Nov-Dec;25(6C):4463-9
    1. Neuroendocrinology. 2006;84(3):155-7
    1. Endocr Relat Cancer. 2005 Dec;12(4):1083-92
    1. Gastroenterology. 2005 May;128(6):1717-51
    1. Gastroenterology. 1999 Mar;116(3):532-42
    1. Hum Pathol. 1996 Nov;27(11):1124-34
    1. Cancer. 2003 Feb 15;97(4):934-59
    1. Neuroendocrinology. 2006;83(5-6):380-6
    1. Ann Surg Oncol. 2007 Feb;14(2):396-404
    1. Am J Gastroenterol. 1998 Mar;93(3):422-8
    1. Ann Oncol. 2004 Jun;15(6):966-73
    1. Neuroendocrinology. 2004;80(4):244-51
    1. Acta Oncol. 2004;43(7):617-25
    1. Dis Colon Rectum. 2005 Dec;48(12):2264-71
    1. Ann Oncol. 2005 Aug;16(8):1374-80
    1. Ann Surg. 2004 Jul;240(1):117-22
    1. Best Pract Res Clin Endocrinol Metab. 2007 Mar;21(1):15-31

Source: PubMed

스폰서 및 공동 작업자

건강 상태

약물 개입

3
구독하다