Molar incisor hypomineralization, prevalence, and etiology

Sulaiman Mohammed Allazzam, Sumer Madani Alaki, Omar Abdel Sadek El Meligy, Sulaiman Mohammed Allazzam, Sumer Madani Alaki, Omar Abdel Sadek El Meligy

Abstract

Aim. To evaluate the prevalence and possible etiological factors associated with molar incisor hypomineralization (MIH) among a group of children in Jeddah, Saudi Arabia. Methods. A group of 8-12-year-old children were recruited (n = 267) from the Pediatric Dental Clinics at the Faculty of Dentistry, King Abdulaziz University. Children had at least one first permanent molar (FPM), erupted or partially erupted. Demographic information, children's medical history, and pregnancy-related data were obtained. The crowns of the FPM and permanent incisors were examined for demarcated opacities, posteruptive breakdown (PEB), atypical restorations, and extracted FPMs. Children were considered to have MIH if one or more FPM with or without involvement of incisors met the diagnostic criteria. Results. MIH showed a prevalence of 8.6%. Demarcated opacities were the most common form. Maxillary central incisors were more affected than mandibular (P = 0.01). The condition was more prevalent in children with history of illnesses during the first four years of life including tonsillitis (P = 0.001), adenoiditis (P = 0.001), asthma (P = 0.001), fever (P = 0.014), and antibiotics intake (P = 0.001). Conclusions. The prevalence of MIH is significantly associated with childhood illnesses during the first four years of life including asthma, adenoid infections, tonsillitis, fever, and antibiotics intake.

Figures

Figure 1
Figure 1
Diagnostic criteria of molar incisor hypomineralization. (a) Demarcate opacities (incisors). (b) Posteruptive breakdown (molars). (c) Atypical restorations (molars). (d) Extracted molars.
Figure 2
Figure 2
Prevalence of MIH in maxillary and mandibular permanent index teeth. The prevalence of MIH was higher in maxillary compared to mandibular central incisors (P = 0.01).
Figure 3
Figure 3
Prevalence of MIH in each permanent index tooth. Upper central incisors were more affected by MIH than lower central incisors (P = 0.01).

References

    1. Weerheijm KL, Jälevik B, Alaluusua S. Molar-incisor hypomineralisation. Caries Research. 2001;35(5):390–391.
    1. Koch G, Hallonsten AL, Ludvigsson N, Hansson BO, Holst A, Ullbro C. Epidemiologic study of idiopathic enamel hypomineralization in permanent teeth of Swedish children. Community Dentistry and Oral Epidemiology. 1987;15(5):279–285.
    1. Wogelius P, Haubek D, Poulsen S. Prevalence and distribution of demarcated opacities in permanent 1st molars and incisors in 6 to 8-year-old Danish children. Acta Odontologica Scandinavica. 2008;66(1):58–64.
    1. Weerheijm KL. Molar incisor hypomineralization (MIH): clinical presentation, aetiology and management. Dental Update. 2004;31(1):9–12.
    1. Fayle SA. Molar incisor hypomineralization: restorative management. European Journal of Paediatric Dentistry. 2003;9:121–126.
    1. Jälevik B, Norén JG, Klingberg G, Barregård L. Etiologic factors influencing the prevalence of demarcated opacities in permanent first molars in a group of Swedish children. European Journal of Oral Sciences. 2001;109(4):230–234.
    1. Weerheijm KL, Duggal M, Mejare I, et al. Judgment criteria for molar incisor hypomineralization (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. European Journal of Paediatric Dentistry. 2003;4(3):110–113.
    1. Leppäniemi A, Lukinmaa PL, Alaluusua S. Nonfluoride hypomineralizations in the permanent first molars and their impact on the treatment need. Caries Research. 2001;35(1):36–40.
    1. Mejàre I, Bergman E, Grindefjord M. Hypomineralized molars and incisors of unknown origin: treatment outcome at age 18 years. International Journal of Paediatric Dentistry. 2005;15(1):20–28.
    1. Jälevik B, Norén JG. Enamel hypomineralization of permanent first molars: a morphological study and survey of possible aetiological factors. International Journal of Paediatric Dentistry. 2000;10(4):278–289.
    1. Alaluusua S, Bäckman B, Brook AH, Lukinmaa PL. Developmental defects of dental hard tissue and their treatment. In: Koch G, Poulsen S, editors. Pediatric Dentistry: A Clinical Approach. 2nd edition. Copenahgen, Denmark: Munksgaard; 2001. pp. 273–299.
    1. Jälevik B, Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralization of their permanent first molars. International Journal of Paediatric Dentistry. 2002;12(1):24–32.
    1. Jälevik B, Möller M. Evaluation of spontaneous space closure and development of permanent dentition after extraction of hypomineralized permanent first molars. International Journal of Paediatric Dentistry. 2007;17(5):328–335.
    1. da Costa-Silva CM, Jeremias F, de Souza JF, Cordeiro RDCL, Santos-Pinto L, Zuanon ACC. Molar incisor hypomineralization: prevalence, severity and clinical consequences in Brazilian children. International Journal of Paediatric Dentistry. 2010;20(6):426–434.
    1. Ghanim A, Morgan M, Mariño R, Bailey D, Manton D. Molar-incisor hypomineralisation: prevalence and defect characteristics in Iraqi children. International Journal of Paediatric Dentistry. 2011;21(6):413–421.
    1. Calderara PC, Gerthoux PM, Mocarelli P, Lukinmaa PL, Tramacere PL, Alaluusua S. The prevalence of Molar Incisor Hypomineralisation (MIH) in a group of Italian school children. European Journal of Paediatric Dentistry. 2005;6(2):79–83.
    1. Fteita D, Ali A, Alaluusua S. Molar-incisor hypomineralization (MIH) in a group of school-aged children in Benghazi, Libya. European Archives of Paediatric Dentistry. 2006;7(2):92–95.
    1. van Amerongen WE, Kreulen CM. Cheese molars: a pilot study of the etiology of hypocalcifications in first permanent molars. ASDC Journal of Dentistry for Children. 1995;62(4):266–269.
    1. Whitford GM, Angmar-Månsson B. Fluorosis-like effects of acidosis, but not NH+4, on rat incisor enamel. Caries Research. 1995;29(1):20–25.
    1. Sui W, Boyd C, Wright JT. Altered pH regulation during enamel development in the cystic fibrosis mouse incisor. Journal of Dental Research. 2003;82(5):388–392.
    1. Rehman Q, Lane NE. Effect of glucocorticoids on bone density. Medical and Pediatric Oncology. 2003;41(3):212–216.
    1. Pawlicki R, Knychalska-Karwin Z, Stankiewicz D, Jakób-Dolezal K, Karwan T. Disturbances of mineral metabolism in teeth of rats receiving corticosteroids for 3 generations. Folia Histochemica et Cytobiologica. 1992;30(2):75–78.
    1. Tung K, Fujita H, Yamashita Y, Takagi Y. Effect of turpentine-induced fever during the enamel formation of rat incisor. Archives of Oral Biology. 2006;51(6):464–470.
    1. Yamaguti PM, Arana-Chavez VE, Acevedo AC. Changes in amelogenesis in the rat incisor following short-term hypocalcaemia. Archives of Oral Biology. 2005;50(2):185–188.
    1. Robinson C, Connell S, Brookes SJ, Kirkham J, Shore RC, Smith DAM. Surface chemistry of enamel apatite during maturation in relation to pH: implications for protein removal and crystal growth. Archives of Oral Biology. 2005;50(2):267–270.

Source: PubMed

스폰서 및 공동 작업자

건강 상태

약물 개입

3
구독하다