Vaccination coverage and factors associated with adherence to the vaccination schedule in young children of a rural area in Burkina Faso

Moubassira Kagoné, Maurice Yé, Eric Nébié, Ali Sie, Anja Schoeps, Heiko Becher, Olaf Muller, Ane Baerent Fisker, Moubassira Kagoné, Maurice Yé, Eric Nébié, Ali Sie, Anja Schoeps, Heiko Becher, Olaf Muller, Ane Baerent Fisker

Abstract

Background: Vaccination is an important tool for reducing infectious disease morbidity and mortality. In the past, less than 80% of children 12-23 months of age were fully immunized in Burkina Faso.

Objectives: To describe coverage and assess factors associated with adherence to the vaccination schedule in rural area Burkina Faso.

Methods: The study population was extracted from the Nouna Health and Demographic surveillance system cohort. Data from four rounds of interviews conducted between November 2012 and June 2014 were considered. This study included 4016 children aged 12-23 months. We assessed the effects of several background factors, including sex, factors reflecting access to health care (residence, place of birth), and maternal factors (age, education, marital status), on being fully immunized defined as having received Bacillus Calmette-Guérin (BCG), three doses of diphtheria-tetanus-pertussis and oral polio vaccine, and measles vaccine by 12 months of age. The associations were studied using binomial regression to derive prevalence ratios (PRs) in univariate and multivariate regression models.

Results: The full vaccination coverage increased significantly over time (72% in 2012, 79% in 2013, and 81% in 2014, p = 0.003), and the coverage was significantly lower in urban than in rural areas (PR 0.84; 0.80-0.89). Vaccination coverage was neither influenced by sex nor influenced by place of birth or by maternal factors.

Conclusion: The study documented a further improvement in full vaccination coverage in Burkina Faso in recent years and better vaccination coverage in rural than in urban areas. The organization of healthcare systems with systematic outreach activities in the rural areas may explain the difference between rural and urban areas.

Keywords: Health and demographic surveillance systems; expended programme on immunization; risk factors; vaccination coverage; vaccination schedule.

Conflict of interest statement

No potential conflict of interest was reported by the authors.

Figures

Figure 1.
Figure 1.
Vaccination coverage curves for children in Nouna HDSS 2012–2014 overall and subdivided by children who were fully immunized (FIC) and not FIC. Kaplan–Meier survival curves indicate vaccination coverage at specific ages. Black line: BCG vaccination; red lines: vaccination with pentavalent vaccines; blue lines: oral polio vaccine and green lines: measles vaccine.

References

    1. Plotkin S, Orenstein W, Offit PA.. Vaccines. Vol. 5 Philadelphia: Saunders; 2008.
    1. Andre FE, Booy R, Bock HL, et al. Vaccination greatly reduces disease, disability, death and inequity worldwide. Bull World Health Organ. 2008;86:140–9.
    1. Tagbo BN, Uleanya ND, Nwokoye IC, et al. Mothers’ knowledge, perception and practice of childhood immunization in Enugu. Niger J Paediatr. 2012;39.
    1. Duclos P, Okwo-Bele JM, Gacic-Dobo M, et al. Global immunization: status, progress, challenges and future. BMC Int Health Hum Rights. 2009;9:S2.
    1. World Health Organisation Fact sheet: immunization coverage [cited 2017. October 04] Available from: .
    1. Black RE, Cousens S, Johnson HL, et al. Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet. 2010;375:1969–1987.
    1. World Health Organisation Vaccination recommendations. [cited 2017 Oct 04]. Available from:
    1. World Health Organization Global Vaccine Action Plan 2011-2020. [cited 2017 Oct 04]. Available from: .
    1. Subaiya S, Dumolard L, Lydon P, et al. Global routine vaccination coverage, 2014. MMWR Morbidity and Mortality Weekly Report. 2015;64:1252–1255.
    1. Fatiregun AA, Okoro AO. Maternal determinants of complete child immunization among children aged 12-23 months in a southern district of Nigeria. Vaccine. 2012;30:730–736.
    1. Sia D, Fournier P, Sondo BK. [Local culture of vaccination: the role of central authorities in the health of the rural population in Burkino Faso]. Glob Health Promot. 2011;18:68–80.
    1. Babirye JN, Rutebemberwa E, Kiguli J, et al. More support for mothers: a qualitative study on factors affecting immunisation behaviour in Kampala, Uganda. BMC Public Health. 2011;11:723.
    1. Wiysonge CS, Uthman OA, Ndumbe PM, et al. Individual and contextual factors associated with low childhood immunisation coverage in sub-Saharan Africa: a multilevel analysis. PloS One. 2012;7:e37905.
    1. Hadler SC, Dietz V, Okwo-Bele JM, et al. Immunization in developing countries In: Orenstein W, Offit PA, Plotkin S, editors. Vaccines. Philadelphia: Saunders Elsevier; 2008.
    1. Sanou A, Simboro S, Kouyate B, et al. Assessment of factors associated with complete immunization coverage in children aged 12-23 months: a cross-sectional study in Nouna district, Burkina Faso. BMC Int Health Hum Rights. 2009;9:S10.
    1. Ojikutu RK. Beliefs, knowledge and perception of parents to peadeatric vaccination in Lagos State, Nigeria. J Manag Sustainability. 2012;2.
    1. Sia D, Kobiane JF, Sondo BK, et al. [Individual and environmental characteristics associated with immunization of children in rural areas in Burkina Faso: a multi-level analysis]. Sante. 2007;17:201–206.
    1. Ministère de la santé, Secrétariat général, Direction générale de la santé, Direction de la prévention par les vaccinations Revue Approfondie du PEV 2009. Burkina Faso: 2010.
    1. Thysen SM, Byberg S, Pedersen M, et al. BCG coverage and barriers to BCG vaccination in Guinea-Bissau: an observational study. BMC Public Health. 2014;14:1037.
    1. Byberg S, Fisker AB, Rodrigues A, et al. Household experience and costs of seeking measles vaccination in rural Guinea-Bissau. Trop Med Int Health. 2017;22:12–20.
    1. Higgins JP, Soares-Weiser K, Lopez-Lopez JA, et al. Association of BCG, DTP, and measles containing vaccines with childhood mortality: systematic review. Bmj. 2016;355:i5170.
    1. Sie A, Louis VR, Gbangou A, et al. The health and demographic surveillance system (HDSS) in Nouna, Burkina Faso, 1993-2007. Global Health Action. 2010;3:5284.
    1. Sie A, Niamba L, Ye M, et al. Rapport annuel: Système de surveillance démographique et de sante (SSDS) de Nouna CRSN. 2011.
    1. Ouedraogo N, Kagone M, Sie A, et al. Immunization coverage in young children: a study nested into a health and demographic surveillance system in Burkina Faso. J Trop Pediatr. 2013;59:187–194.
    1. Schoeps A, Ouedraogo N, Kagone M, et al. Socio-demographic determinants of timely adherence to BCG, Penta3, measles, and complete vaccination schedule in Burkina Faso. Vaccine. 2013;32:96–102.
    1. Fadnes LT, Jackson D, Engebretsen IM, et al. Vaccination coverage and timeliness in three South African areas: a prospective study. BMC Public Health. 2011;11:404.
    1. Shemwell SA, Peratikos MB, Gonzalez-Calvo L, et al. Determinants of full vaccination status in children aged 12-23 months in Gurue and Milange districts, Mozambique: results of a population-based cross-sectional survey. Int Health. 2017;9:234–242.
    1. Ministère de la Santé Annuaire statistique 2013. 2014.
    1. Burton A, Monasch R, Lautenbach B, et al. WHO and UNICEF estimates of national infant immunization coverage: methods and processes. Bull World Health Organ. 2009;87:535–541.
    1. Mutua MK, Kimani-Murage E, Ettarh RR. Childhood vaccination in informal urban settlements in Nairobi, Kenya: who gets vaccinated? BMC Public Health. 2011;11:6.
    1. Breiman RF, Streatfield PK, Phelan M, et al. Effect of infant immunisation on childhood mortality in rural Bangladesh: analysis of health and demographic surveillance data. Lancet. 2004;364:2204–2211.
    1. Fisker AB, Hornshoj L, Rodrigues A, et al. Effects of the introduction of new vaccines in Guinea-Bissau on vaccine coverage, vaccine timeliness, and child survival: an observational study. The Lancet Global Health. 2014;2:e478–e487.
    1. Torun SD, Bakirci N. Vaccination coverage and reasons for non-vaccination in a district of Istanbul. BMC Public Health. 2006;6:125.
    1. Agarwal S, Bhanot A, Goindi G. Understanding and addressing childhood immunization coverage in urban slums. Indian Pediatr. 2005;42:653–663.
    1. Hutchins SS, Jansen HA, Robertson SE, et al. Studies of missed opportunities for immunization in developing and industrialized countries. Bull World Health Organ. 1993;71:549–560.
    1. Glanz JM, Narwaney KJ, Newcomer SR, et al. Association between undervaccination with diphtheria, tetanus toxoids, and acellular pertussis (DTaP) vaccine and risk of pertussis infection in children 3 to 36 months of age. JAMA Pediatr. 2013;167:1060–1064.
    1. Aaby P, Roth A, Ravn H, et al. Randomized trial of BCG vaccination at birth to low-birth-weight children: beneficial nonspecific effects in the neonatal period? J Infect Dis. 2011;204:245–252.
    1. Biering-Sørensen S, Aaby P, Lund N, et al. Early BCG-Denmark and neonatal mortality among infants weighing <2500 g: a randomized controlled trial. Clin Infect Dis. 2017;65:1183–1190.
    1. Biering-Sorensen S, Aaby P, Napirna BM, et al. Small randomized trial among low-birth-weight children receiving Bacillus Calmette-Gueerin vaccination at first health center contact. Pediatr Infect Dis J. 2012;31:306–308.
    1. Lawn JE, Cousens S, Zupan J. 4 million neonatal deaths: when? Where? Why? Lancet. 2005;365:891–900.

Source: PubMed

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