Individual cognitive behavioral therapy for insomnia in breast cancer survivors: a randomized controlled crossover pilot study

Lavinia Fiorentino, John R McQuaid, Lianqi Liu, Loki Natarajan, Feng He, Monique Cornejo, Susan Lawton, Barbara A Parker, Georgia R Sadler, Sonia Ancoli-Israel, Lavinia Fiorentino, John R McQuaid, Lianqi Liu, Loki Natarajan, Feng He, Monique Cornejo, Susan Lawton, Barbara A Parker, Georgia R Sadler, Sonia Ancoli-Israel

Abstract

Purpose: Estimates of insomnia in breast cancer patients are high, with reports of poor sleep lasting years after completion of cancer treatment. This randomized controlled crossover pilot study looked at the effects of individual cognitive behavioral therapy for insomnia (IND-CBT-I) on sleep in breast cancer survivors.

Patients and methods: Twenty-one participants were randomly assigned to either a treatment group (six weekly IND-CBT-I sessions followed by six weeks of follow up) or a delayed treatment control group (no treatment for six weeks followed by six weekly IND-CBT-I sessions). Of these, 14 participants completed the pilot study (six in the treatment group and eight in the delayed treatment control group).

Results: Self-rated insomnia was significantly improved in the treatment group compared to the waiting period in the delayed treatment control group. The pooled pre-post-IND-CBT-I analyses revealed improvements in self-rated insomnia, sleep quality, and objective measures of sleep.

Conclusions: These preliminary results suggest that IND-CBT-I is appropriate for improving sleep in breast cancer survivors. Individual therapy in a clinic or private practice may be a more practical option for this population as it is more easily accessed and readily available in an outpatient setting.

Keywords: breast cancer; cognitive behavioral therapy; insomnia.

Figures

Figure 1
Figure 1
Participant flowchart. Abbreviation: IND-CBT-I, individual cognitive behavioral therapy for insomnia.
Figure 2
Figure 2
Insomnia severity index by group (means and standard deviations). Abbreviations: IND-CBT-I, individual cognitive behavioral therapy for insomnia; Txc, treatment condition; ISI, insomnia severity index; TxC, treatment + follow-up group; DTxC, waiting + treatment group; P, phase.
Figure 3
Figure 3
Pittsburgh sleep quality index by group and week of study. Abbreviations: PSQI, Pittsburgh sleep quality index; BL, baseline [ie, phase 0]; IND-CBT-I, individual cognitive behavioral therapy for insomnia; TxC, treatment condition; ISI, insomnia severity index; TxC, treatment + follow-up group; DTxC, waiting + treatment group.

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Source: PubMed

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