Management of chronic pain after hernia repair

Kristoffer Andresen, Jacob Rosenberg, Kristoffer Andresen, Jacob Rosenberg

Abstract

Chronic pain following inguinal hernia repair is a common problem and feared complication. Up to 16% of people experience chronic pain following the repair of a groin hernia. The aim of this review was to provide an overview of treatment strategies for patients with chronic pain following inguinal hernia repair based on best practice guidelines and current clinical routines. The optimal management of chronic pain following inguinal hernia surgery should begin with a thorough clinical examination to rule out other causes of chronic pain and to rule out a recurrence. A scaled approach to treatment is recommended. Initially, watchful waiting can be tried if it can be tolerated by the patient and then systemic painkillers, escalating to blocks, and surgery as the final option. Surgery should include mesh removal and triple neurectomy following anterior approaches or mesh and tack removal following a posterior approach. The diagnosis and treatment strategies should be performed by or discussed with experts in the field.

Keywords: chronic pain; inguinal hernia; management; pharmacology; radio frequency; surgery.

Conflict of interest statement

Disclosure The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Proposed treatment options for chronic pain following inguinal hernia repair. Note: A scaled approach is suggested if the patient’s condition allows it. Abbreviations: NSAID; nonsteroidal anti-inflammatory drug; SSRI, selective serotonin reuptake inhibitor; SNRI, serotonin–norepinephrine reuptake inhibitor.

References

    1. Kingsnorth A. Treating inguinal hernias. BMJ. 2004;328(7431):59–60.
    1. Aasvang EK, Gmaehle E, Hansen JB, et al. Predictive risk factors for persistent postherniotomy pain. Anesthesiology. 2010;112(4):957–969.
    1. Andresen K, Burcharth J, Fonnes S, et al. Chronic pain after inguinal hernia repair with the ONSTEP versus the Lichtenstein technique, results of a double-blinded multicenter randomized clinical trial. Langenbecks Arch Surg. 2017;402(2):213–218.
    1. Alfieri S, Amid PK, Campanelli G, et al. International guidelines for prevention and management of post-operative chronic pain following inguinal hernia surgery. Hernia. 2011;15(3):239–249.
    1. The HerniaSurge Group International Guidelines for Groin Hernia-Management. Hernia. 2018;22(1):1–165.
    1. Rosenberg J, Bisgaard T, Kehlet H, et al. Danish Hernia Database Danish Hernia Database recommendations for the management of inguinal and femoral hernia in adults. Dan Med Bull. 2011;58(2):C4243.
    1. Shouldice EB. The shouldice repair for groin hernias. Surg Clin North Am. 2003;83(5):1163–1187.
    1. Fitzgibbons RJ, Jr, Forse RA. Clinical practice. Groin hernias in adults. N Engl J Med. 2015;372(8):756–763.
    1. Bischoff JM, Aasvang EK, Kehlet H, Werner MU. Does nerve identification during open inguinal herniorrhaphy reduce the risk of nerve damage and persistent pain? Hernia. 2012;16(5):573–577.
    1. Andresen K, Fenger AQ, Burcharth J, Pommergaard HC, Rosenberg J. Mesh fixation methods and chronic pain after transabdominal preperitoneal (TAPP) inguinal hernia surgery: a comparison between fibrin sealant and tacks. Surg Endosc. 2017;31(10):4077–4084.
    1. Burgmans JP, Voorbrood CE, Simmermacher RK, et al. Long-term results of a randomized double-blinded prospective trial of a lightweight (Ultrapro) versus a heavyweight mesh (Prolene) in laparoscopic total extraperitoneal inguinal hernia repair (TULP-trial) Ann Surg. 2016;263(5):862–866.
    1. Sajid MS, Leaver C, Baig MK, Sains P. Systematic review and meta-analysis of the use of lightweight versus heavyweight mesh in open inguinal hernia repair. Br J Surg. 2012;99(1):29–37.
    1. Colvin HS, Rao A, Cavali M, Campanelli G, Amin AI. Glue versus suture fixation of mesh during open repair of inguinal hernias: a systematic review and meta-analysis. World J Surg. 2013;37(10):2282–2292.
    1. Campanelli G, Pascual MH, Hoeferlin A, et al. Randomized, controlled, blinded trial of Tisseel/Tissucol for mesh fixation in patients undergoing Lichtenstein technique for primary inguinal hernia repair: results of the TIMELI trial. Ann Surg. 2012;255(4):650–657.
    1. Werner MU, Kongsgaard UE. I. Defining persistent post-surgical pain: is an update required? Br J Anaesth. 2014;113(1):1–4.
    1. Schug SA, Pogatzki-Zahn M. Chronic pain after surgery or injury. Pain Clin Updates. 2011;14(1):1–5.
    1. Amid PK. Radiologic images of meshoma a new phenomenon causing chronic pain after prosthetic repair of abdominal wall hernias. JAMA Surg. 2004;139(12):1297–1298.
    1. McCarthy MJ, Jonasson O, Chang CH, et al. Assessment of patient functional status after surgery. J Am Coll Surg. 2005;201(2):171–178.
    1. Franneby U, Gunnarsson U, Andersson M, et al. Validation of an Inguinal Pain Questionnaire for assessment of chronic pain after groin hernia repair. Br J Surg. 2008;95(4):488–493.
    1. Heniford BT, Walters AL, Lincourt AE, Novitsky YW, Hope WW, Kercher KW. Comparison of generic versus specific quality-of-life scales for mesh hernia repairs. J Am Coll Surg. 2008;206(4):638–644.
    1. Chen DC, Hiatt JR, Amid PK. Operative management of refractory neuropathic inguinodynia by a laparoscopic retroperitoneal approach. JAMA Surg. 2013;148(10):962–967.
    1. Álvarez R. Dermatome mapping: preoperative and postoperative assessment. In: Jacob B, Chen D, Ramshaw B, Towfigh S, editors. The SAGES Manual of Groin Pain. Cham: Springer; 2016. pp. 277–292.
    1. Wylde V, Dennis J, Beswick AD, et al. Systematic review of management of chronic pain after surgery. Br J Surg. 2017;104(10):1293–1306.
    1. Werner MU. Management of persistent postsurgical inguinal pain. Langenbecks Arch Surg. 2014;399(5):559–569.
    1. Lange JF, Kaufmann R, Wijsmuller AR, et al. An international consensus algorithm for management of chronic postoperative inguinal pain. Hernia. 2015;19(1):33–43.
    1. Hakeem A, Shanmugam V. Current trends in the diagnosis and management of post-herniorraphy chronic groin pain. World J Gastrointest Surg. 2011;3(6):73–81.
    1. Courtney CA, Duffy K, Serpell MG, O’Dwyer PJ. Outcome of patients with severe chronic pain following repair of groin hernia. Br J Surg. 2002;89(10):1310–1314.
    1. Oberg S, Andresen K, Rosenberg J. Gradual decline in prevalence of chronic pain after laparoscopic groin hernia repair: a nationwide cross-sectional questionnaire study. 2018 In press.
    1. Bjurstrom MF, Nicol AL, Amid PK, Chen DC. Pain control following inguinal herniorrhaphy: current perspectives. J Pain Res. 2014;7:277–290.
    1. Bischoff JM, Ringsted TK, Petersen M, Sommer C, Uceyler N, Werner MU. A capsaicin (8%) patch in the treatment of severe persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled trial. PLoS One. 2014;9(10):e109144.
    1. Bischoff JM, Petersen M, Uceyler N, Sommer C, Kehlet H, Werner MU. Lidocaine patch (5%) in treatment of persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial. Anesthesiology. 2013;119(6):1444–1452.
    1. Clarke H, Bonin RP, Orser BA, Englesakis M, Wijeysundera DN, Katz J. The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis. Anesth Analg. 2012;115(2):428–442.
    1. Chaparro LE, Smith SA, Moore RA, Wiffen PJ, Gilron I. Pharma-cotherapy for the prevention of chronic pain after surgery in adults. Cochrane Database Syst Rev. 2013;7:CD008307.
    1. Bischoff JM, Koscielniak-Nielsen ZJ, Kehlet H, Werner MU. Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial. Anesth Analg. 2012;114(6):1323–1329.
    1. Wijayasinghe N, Ringsted TK, Bischoff JM, Kehlet H, Werner MU. The role of peripheral afferents in persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial of ultrasound-guided tender point blockade. Br J Anaesth. 2016;116(6):829–837.
    1. Verhagen T, Loos MJA, Scheltinga MRM, Roumen RMH. The Groin-Pain trial: a randomized controlled trial of injection therapy versus neurectomy for postherniorraphy inguinal neuralgia. Ann Surg. 2017 Apr;:26. Epub.
    1. Makharita MY, Amr YM. Pulsed radiofrequency for chronic inguinal neuralgia. Pain Physician. 2015;18(2):E147–E155.
    1. Kastler A, Aubry S, Piccand V, Hadjidekov G, Tiberghien F, Kastler B. Radiofrequency neurolysis versus local nerve infiltration in 42 patients with refractory chronic inguinal neuralgia. Pain Physician. 2012;15(3):237–244.
    1. Schu S, Gulve A, ElDabe S, et al. Spinal cord stimulation of the dorsal root ganglion for groin pain-a retrospective review. Pain Pract. 2015;15(4):293–299.
    1. Levine AB, Steven DA, Parrent AG, MacDougall KW. Successful long-term nerve root stimulation for chronic neuropathic pain: a real world, single center Canadian experience. Pain Physician. 2017;20(2):95–106.
    1. Schwartz JS, Strosberg DS, Renton DB. Chronic groin pain following anterior hernia surgery. In: Jacob BP, Chen DC, Ramshaw B, Towfigh S, editors. The SAGES Manual of Groin Pain. Cham: Springer; 2016. pp. 211–219.
    1. Moore AM, Bjurstrom MF, Hiatt JR, Amid PK, Chen DC. Efficacy of retroperitoneal triple neurectomy for refractory neuropathic inguinodynia. Am J Surg. 2016;212(6):1126–1132.
    1. Kockerling F, Berger D, Jost JO. What is a certified hernia center? The example of the German hernia society and German society of general and visceral surgery. Front Surg. 2014;1:26.
    1. Nolsøe A, Andresen K, Rosenberg J. Repair of recurrent hernia is often performed at a different clinic. Hernia. 2016;20(6):783–787.

Source: PubMed

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