Impact of lower extremity venous ulcers due to chronic venous insufficiency on quality of life

Sotirios A Koupidis, Kosmas I Paraskevas, Vassilios Stathopoulos, Dimitri P Mikhailidis, Sotirios A Koupidis, Kosmas I Paraskevas, Vassilios Stathopoulos, Dimitri P Mikhailidis

Abstract

Lower extremity venous ulcers comprise a complex medical and social issue. The conservative and/or surgical management of venous ulcers is often inadequate. In addition, the psychosocial aspect of the disease is often overlooked and most often undertreated. Common symptoms such as pain, low self-esteem and patient isolation are usually not recognized and therefore not adequately managed.This mini-review summarizes the current data on the management of lower extremity venous ulcers and their impact on the quality of life of these patients.

Keywords: Venous leg ulcers; lower extremity venous ulcers.; quality of life.

References

    1. Chiesa R, Marone EM, Limoni C, Volonté M, Schaefer E, Petrini O. Effect of chronic venous insufficiency on activities of daily living and quality of life: correlation of demographic factors with duplex ultrasonography findings. Angiology. 2007;58:440–9.
    1. White JV, Ryjewski C. Chronic venous insufficiency. Perspect Vasc Surg Endovasc Ther. 2005;17:319–27.
    1. Eberhardt RT, Raffeto JD. Chronic venous insufficiency. Circulation. 2005;111:2398–409.
    1. Kantor J, Margolis D. Management of leg ulcers. Semin Cutan Med Surg. 2003;22:212–21.
    1. Bongiovanni CM, Hughes MD, Bomengen RW. Accelerated wound healing: multidisciplinary advances in the care of venous leg ulcers. Angiology. 2006;57:139–44.
    1. O’Meara S, Al-Kurdi D, Ovington LG. Antibiotics and antiseptics for venous leg ulcers. Cochrane Database Syst Rev. 2008;1:CD003557.
    1. Al-Kurdi D, Bell-Syer SE, Flemming K. Therapeutic ultrasound for venous leg ulcers. Cochrane Database Syst Rev. 2008;1:CD001180.
    1. Barron GS, Jacob SE, Kirsner RS. Dermatologic complications of chronic venous disease: medical management and beyond. Ann Vasc Surg. 2007;21:652–62.
    1. Herschthal J, Kirsner RS. Current management of venous ulcers: an evidence-based review. Surg Technol Int. 2008;17:77–83.
    1. Heinen MM, Persoon A, van de Kerkhof P, Otero M, van Achterberg T. Ulcer-related problems and health care needs in patients with venous leg ulcerations: a descriptive, cross-sectional study. Int J Nurs Stud. 2007;44:1296–303.
    1. Guarnera G, Tinelli G, Abeni D, Di Pietro C, Sampogna F, Tabolli S. Pain and quality of life in patients with vascular leg ulcers: an Italian multicentre study. J Wound Care. 2007;16:347–51.
    1. Jones JE, Robinson J, Barr W, Carlisle C. Impact of exudates and odour from chronic venous leg ulceration. Nurs Stand. 2008;22:53–4.
    1. Hareendran A, Bradbury A, Budd J, et al. Measuring the impact of venous leg ulcers on quality of life. J Wound Care. 2005;14:53–7.
    1. Van Hecke A, Grypdonck M, Defloor T. Guidelines for the management of venous leg ulcers: a gap analysis. J Eval Clin Pract. 2008 In process citation.
    1. Motykie GD, Caprini JA, Arcelus JI, Reyna JJ, Overom E, Mokhtee D. Evaluation of therapeutic compression stockings in the treatment of chronic venous insufficiency. Dermatol Surg. 1999;25:116–20.
    1. Mayberry JC, Moneta GL, Taylor LM Jr, Porter JM. Fifteen-year results of ambulatory compression therapy for chronic venous ulcers. Surgery. 1991;109:575–81.
    1. Moffatt CJ, Edwards L, Collier M, et al. A randomised controlled 8-week crossover clinical evaluation of the 3M coban 2 layer compression system versus profore to evaluate the product performance in patients with venous leg ulcers. Int Wound J. 2008;5:267–79.
    1. Charles H. Does leg ulcer treatment improve patients’ quality of life? J Wound Care. 2004;13:209–13.
    1. Nelson EA, Mani R, Vowden K. Intermittent pneumatic compression for treating venous leg ulcers. Cochrane Database Syst Rev. 2008;12:CD001899.
    1. Heinen MM, van Achterberg T, op Reimer WS, van de Kerkhof PC, de Laat E. Venous leg ulcer patients: a review of the literature on lifestyle and pain-related interventions. J Clin Nurs. 2004;13:355–66.
    1. Felty CL, Rooke TW. Compression therapy for chronic venous insufficiency. Semin Vasc Surg. 2005;18:36–40.
    1. Belcaro G, Cesarone MR, Errichi BM, et al. Improvement of microcirculation and healing of venous hypertension and ulcers with Crystacide: evaluation with a microcirculatory model, including free radicals, laser doppler flux, and PO2/PCO2 measurements. Angiology. 2007;58:323–8.
    1. Cesarone MR, Belcaro G, Pellegrini L, et al. Venoruton vs Daflon: evaluation of effects on quality of life in chronic venous insufficiency. Angiology. 2006;57:131–8.
    1. Katsenis K. Micronized purified flavonoid fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency. Curr Vasc Pharmacol. 2005;3:1–9.
    1. Bergan JJ. Chronic venous insufficiency and the therapeutic effects of Daflon 500 mg. Angiology. 2005;56(Suppl 1):S21–4.
    1. Cesarone MR, Belcaro G, Rohdewald P, et al. Rapid relief of signs/symptoms in chronic venous microangiopathy with pycnogenol: a prospective, controlled study. Angiology. 2006;57:569–76.
    1. Cesarone MR, Belcaro G, Rohdewald P, et al. Improvement of diabetic microangiopathy with pycnogenol: A prospective, controlled study. Angiology. 2006;57:431–6.
    1. Vinciguerra G, Belcaro G, Cesarone MR, et al. Cramps and muscular pain: prevention with pycnogenol in normal subjects, venous patients, athletes, claudicants and in diabetic microangiopathy. Angiology. 2006;57:331–9.
    1. Cesarone MR, Belcaro G, Pellegrini L, et al. HR, 0–(beta–hydroxyethyl)–rutosides; (Venoruton): rapid relief of signs/symptoms in chronic venous insufficiency and microangiopathy: a prospective, controlled study. Angiology. 2005;56:165–72.
    1. Martinez MJ, Bonfill X, Moreno RM, Vargas E, Capellà D. Phlebotonics for venous insufficiency. Cochrane Database Syst Rev. 2005;20:CD003229.
    1. Leach MJ, Pincombe J, Foster G. Using horsechestnut seed extract in the treatment of venous leg ulcers: a cost–benefit analysis. Ostomy Wound Manage. 2006;52:68–70. 72–4, 76–8.
    1. Leach MJ, Pincombe J, Foster G. Clinical efficacy of horsechestnut seed extract in the treatment of venous ulceration. J Wound Care. 2006;15:159–67.
    1. Suter A, Bommer S, Rechner J. Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies. Adv Ther. 2006;23:179–90.
    1. Streit M, Beleznay Z, Braathen LR. Topical application of the tumour necrosis factor–alpha antibody infliximab improves healing of chronic wounds. Int Wound J. 2006;3:171–9.
    1. Welch HJ. Surgical options for the treatment of venous ulcers. Vasc Endovascular Surg. 2004;38:195–202.
    1. Rosales A, Slagsvold CE, Kroese AJ, Stranden E, Risum Ø, Jørgensen JJ. External venous valve plasty (EVVP) in patients with primary chronic venous insufficiency (PCVI) Eur J Vasc Endovasc Surg. 2006;32:570–6.
    1. Wang SM, Hu ZJ, Li SQ, Huang XL, Ye CS. Effect of external valvuloplasty of the deep vein in the treatment of chronic venous insufficiency of the lower extremity. J Vasc Surg. 2006;44:1296–300.
    1. Geselschap JH, van Zuiden JM, Toonder IM, Wittens CH. In vitro evaluation of a new autologous valve-stent for deep venous incompetence. J Endovasc Ther. 2006;13:762–9.
    1. Mussa FF, Peden EK, Zhou W, Lin PH, Lumsden AB, Bush RL. Iliac vein stenting for chronic venous insufficiency. Tex Heart Inst J. 2007;34:60–6.
    1. Neglen P, Hollis KC, Raju S. Combined saphenous ablation and iliac stent placement for complex severe chronic venous disease. J Vasc Surg. 2006;44:828–33.
    1. Gohel MS, Barwell JR, Wakely C, et al. The influence of superficial venous surgery and compression on incompetent calf perforators in chronic venous leg ulceration. Eur J Vasc Endovasc Surg. 2005;29:78–82.
    1. Gohel MS, Barwell JR, Earnshaw JJ, et al. Randomized clinical trial of compression plus surgery versus compression alone in chronic venous ulceration (ESCHAR study)--haemodynamic and anatomical changes. Br J Surg. 2005;92:291–7.
    1. Puggioni A, Kalra M, Gloviczki P. Superficial vein surgery and SEPS for chronic venous insufficiency. Semin Vasc Surg. 2005;18:41–8.
    1. Baron HC, Wayne MG, Santiago C, et al. Treatment of severe chronic venous insufficiency using the subfascial endoscopic perforator vein procedure. Surg Endosc. 2005;19:126–9.
    1. Puggioni A, Kalra M, Gloviczki P. Superficial vein surgery and SEPS for chronic venous insufficiency. Semin Vasc Surg. 2005;18:41–8.
    1. Bergan JJ, Pascarella L. Severe chronic venous insufficiency: primary treatment with sclerofoam. Semin Vasc Surg. 2005;18:49–56.
    1. Jones JE, Nelson EA. Skin grafting for venous leg ulcers. Cochrane Database Syst Rev. 2007;2:CD001737.
    1. Marston W. Evaluation and treatment of leg ulcers associated with chronic venous insufficiency. Clin Plast Surg. 2007;34:717–30.
    1. Jankunas V, Bagdonas R, Samsanavicius D, Rimdeika R. The influence of surgical treatment for chronic leg ulcers on the quality dynamics of the patient’s life. Acta Chir Belg. 2007;107:386–96.
    1. Jankunas V, Rimdeika R, Jasenas M, Samsanavicius D. Changes in patient’s quality of life comparing conservative and surgical treatment of venous leg ulcers. Medicina (Kaunas) 2004;40:731–9.

Source: PubMed

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