Multiple breath washout test data for healthy controls

Abstract

This article includes pulmonary function data collected via multiple breath nitrogen washout for 103 healthy U.S. adults recruited at National Jewish Health in Denver, Colorado. Testing was performed by certified technicians and reviewed by expert pulmonologists for quality and consistency. Data were collected from a diverse population that included 52 males and 51 females with an average age of 39 years (range 20-77 years). Participants were of non-Hispanic White (85%), African-American/Black (6%), Hispanic (4%), more than one race (4%) or American Indian/Alaskan Native (1%) race/ethnicity. The majority were never smokers (85%), but 12% were former smokers and 3% were current smokers. Height, weight, and body mass index (BMI) were collected in addition to multiple breath washout (MBW) test parameters such as the lung clearance index (LCI) score.

Keywords: Healthy control; Lung clearance index; Lung function; Multiple breath washout.

Conflict of interest statement

Cecile Rose receives research grant funding from the U.S. Department of Defense as part of a large multi-site, multi-investigator study on mechanisms of lung epithelial injury. Silpa Krefft is employed by the U.S. Department of Veterans Affairs (DVA) and receives research grant funding from the DVA. Both Drs. Rose and Krefft have participated in medicolegal depositions to provide expert testimony on patients for whom they have rendered medical opinions; however, they have received no personal income or compensation for these medicolegal efforts, all of which have been reimbursed to National Jewish Health.

© 2020 The Authors.

Figures

Fig. A1

Distribution of lung clearance index scores among never smoking controls with body mass index

Fig. A2

Distribution of multiple breath washout parameters by body mass index category