Proton beam and prostate cancer: An evolving debate

Abstract

This paper evaluates the reasons behind the rise in the use of proton beam for prostate cancer, the economics drivers behind it, and the evidence that exists to support it. It concludes that clinical outcome data underlying the notion that this is a superior treatment remains sparse and discusses what is needed to fill in the gaps.

Keywords: Prostate cancer; Proton beam.

Figures

Fig. 1

Comparative planning study showing the difference in dose distribution between opposed lateral, passively scattered proton beams and an intensity modulated photon plan.

Fig. 2

Case-controlled study from the Massachusetts General Hospital comparing patients treated with either high-dose proton beam radiation or low dose-rate brachytherapy. Figure shows cumulative biochemical recurrence rates.