Multidimensional Dyspnea Profile: an instrument for clinical and laboratory research

Robert B Banzett, Carl R O'Donnell, Tegan E Guilfoyle, Mark B Parshall, Richard M Schwartzstein, Paula M Meek, Richard H Gracely, Robert W Lansing, Robert B Banzett, Carl R O'Donnell, Tegan E Guilfoyle, Mark B Parshall, Richard M Schwartzstein, Paula M Meek, Richard H Gracely, Robert W Lansing

Abstract

There is growing awareness that dyspnoea, like pain, is a multidimensional experience, but measurement instruments have not kept pace. The Multidimensional Dyspnea Profile (MDP) assesses overall breathing discomfort, sensory qualities, and emotional responses in laboratory and clinical settings. Here we provide the MDP, review published evidence regarding its measurement properties and discuss its use and interpretation. The MDP assesses dyspnoea during a specific time or a particular activity (focus period) and is designed to examine individual items that are theoretically aligned with separate mechanisms. In contrast, other multidimensional dyspnoea scales assess recalled recent dyspnoea over a period of days using aggregate scores. Previous psychophysical and psychometric studies using the MDP show that: 1) subjects exposed to different laboratory stimuli could discriminate between air hunger and work/effort sensation, and found air hunger more unpleasant; 2) the MDP immediate unpleasantness scale (A1) was convergent with common dyspnoea scales; 3) in emergency department patients, two domains were distinguished (immediate perception, emotional response); 4) test-retest reliability over hours was high; 5) the instrument responded to opioid treatment of experimental dyspnoea and to clinical improvement; 6) convergent validity with common instruments was good; and 7) items responded differently from one another as predicted for multiple dimensions.

Conflict of interest statement

Conflict of interest: Disclosures can be found alongside the online version of this article at erj.ersjournals.com

Copyright ©ERS 2015.

Figures

FIGURE 1
FIGURE 1
Model of the components of dyspnoea underlying the Multidimensional Dyspnea Profile. The division into sensory (SQ) and affective dimensions unpleasantness (A1) and emotional response (A2) (shown on the left) is based on a well-developed conceptual model of pain perception [26]. The division into Immediate and Emotional Response Domains (shown on the right) is based on empirical evidence from emergency department patients [36].

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