Therapist-guided, Internet-based cognitive-behavioural therapy for body dysmorphic disorder (BDD-NET): a feasibility study

Jesper Enander, Volen Z Ivanov, Erik Andersson, David Mataix-Cols, Brjánn Ljótsson, Christian Rück, Jesper Enander, Volen Z Ivanov, Erik Andersson, David Mataix-Cols, Brjánn Ljótsson, Christian Rück

Abstract

Objectives: Cognitive-behavioural therapy (CBT) is an effective treatment for body dysmorphic disorder (BDD). However, most sufferers do not have access to this treatment. One way to increase access to CBT is to administer treatment remotely via the Internet. This study piloted a novel therapist-supported, Internet-based CBT program for BDD (BDD-NET).

Design: Uncontrolled clinical trial.

Participants: Patients (N=23) were recruited through self-referral and assessed face to face at a clinic specialising in obsessive-compulsive and related disorders. Suitable patients were offered secure access to BDD-NET.

Intervention: BDD-NET is a 12-week treatment program based on current psychological models of BDD that includes psychoeducation, functional analysis, cognitive restructuring, exposure and response prevention, and relapse prevention modules. A dedicated therapist provides active guidance and feedback throughout the entire process.

Main outcome measure: The clinician-administered Yale-Brown Obsessive Compulsive Scale for BDD (BDD-YBOCS). Symptom severity was assessed pretreatment, post-treatment and at the 3-month follow-up.

Results: BDD-NET was deemed highly acceptable by patients and led to significant improvements on the BDD-YBOCS (p=<0.001) with a large within-group effect size (Cohen's d=2.01, 95% CI 1.05 to 2.97). At post-treatment, 82% of the patients were classified as responders (defined as≥30% improvement on the BDD-YBOCS). These gains were maintained at the 3-month follow-up. Secondary outcome measures of depression, global functioning and quality of life also showed significant improvements with moderate to large effect sizes. On average, therapists spent 10 min per patient per week providing support.

Conclusions: The results suggest that BDD-NET has the potential to greatly increase access to CBT, at least for low-risk individuals with moderately severe BDD symptoms and reasonably good insight. A randomised controlled trial of BDD-NET is warranted.

Trial registration number: Clinicaltrials.gov registration ID NCT01850433.

Keywords: MENTAL HEALTH; PSYCHIATRY.

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Figures

Figure 1
Figure 1
Participant flow through the study.
Figure 2
Figure 2
Weekly scores on the self-administered Body Dysmorphic Disorder Dimensional Scale, BDD-D (including 95% CIs).

References

    1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th edn Arlington, VA: American Psychiatric Publishing, 2013
    1. Rief W, Buhlmann U, Wilhelm S, et al. . The prevalence of body dysmorphic disorder: a population-based survey. Psychol Med 2006;36:877–85
    1. Buhlmann U, Glaesmer H, Mewes R, et al. . Updates on the prevalence of body dysmorphic disorder: a population-based survey. Psychiatry Res 2010;178:171–5
    1. Koran LM, Abujaoude E, Large MD, et al. . The prevalence of body dysmorphic disorder in the United States adult population. CNS Spectr 2008;13:316–22
    1. Phillips KA, Diaz SF. Gender differences in body dysmorphic disorder. J Nerv Ment Dis 1997;185:570–7
    1. Phillips KA, Coles ME, Menard W, et al. . Suicidal ideation and suicide attempts in body dysmorphic disorder. J Clin Psychiatry 2005;66:717–25
    1. Phillips KA, Menard W, Fay C, et al. . Psychosocial functioning and quality of life in body dysmorphic disorder. Compr Psychiatry 2005;46:254–60
    1. Phillips KA, Menard W, Quinn E, et al. . A 4-year prospective observational follow-up study of course and predictors of course in body dysmorphic disorder. Psychol Med 2013;43:1109–17
    1. Sarwer DB, Crerand CE. Body dysmorphic disorder and appearance enhancing medical treatments. Body Image 2008;5:50–8
    1. Crerand CE, Phillips KA, Menard W, et al. . Nonpsychiatric medical treatment of body dysmorphic disorder. Psychosomatics 2005;46:549–55
    1. Ipser JC, Sander C, Stein DJ. Pharmacotherapy and psychotherapy for body dysmorphic disorder. Cochrane Database of Syst Rev 2009;1:CD005332.
    1. Williams J, Hadjistavropoulos T, Sharpe D. A meta-analysis of psychological and pharmacological treatments for body dysmorphic disorder. Behav Res Ther 2006;44:99–111
    1. Rosen JC, Reiter J, Orosan P. Cognitive-behavioral body image therapy for body dysmorphic disorder. J Consult Clin Psychol 1995;63:263–9
    1. Veale D, Gournay K, Dryden W, et al. . Body dysmorphic disorder: a cognitive behavioural model and pilot randomised controlled trial. Behav Res Ther 1996;34:717–29
    1. Wilhelm S, Phillips KA, Steketee G. A cognitive-behavioral treatment manual for body dysmorphic disorder. New York, NY: Guilford Press, 2013
    1. Wilhelm S, Phillips KA, Fama JM, et al. . Modular cognitive-behavioral therapy for body dysmorphic disorder. Behav Ther 2011;42:624–33
    1. Wilhelm S, Phillips KA, Didie E, et al. . Modular cognitive-behavioral therapy for body dysmorphic disorder: a randomized controlled trial. Behav Ther 2014;45:314–27
    1. Veale D, Anson M, Miles S, et al. . Efficacy of cognitive behaviour therapy versus anxiety management for body dysmorphic disorder: a randomised controlled trial. Psychother Psychosom In press, 2014. doi:
    1. Veale D, Neziroglu F. Body dysmorphic disorder: a treatment manual. Chichester: John Wiley & Sons, 2010
    1. Shapiro DA, Cavanagh K, Lomas H. Geographic inequity in the availability of cognitive behavioural therapy in England and Wales. Behav Cogn Psychother 2003;31:185–92
    1. Marques L, Weingarden HM, Leblanc NJ, et al. . Treatment utilization and barriers to treatment engagement among people with body dysmorphic symptoms. J Psychosom Res 2011;70:286–93
    1. Mojtabai R Trends in contacts with mental health professionals and cost barriers to mental health care among adults with significant psychological distress in the United States: 1997–2002. Am J Public Health 2005;95:2009–14
    1. Buhlmann U Treatment barriers for individuals with body dysmorphic disorder: an internet survey. J Nerv Ment Dis 2011;199:268–71
    1. Cuijpers P, van Straten A, Andersson G. Internet-administered cognitive behavior therapy for health problems: a systematic review. J Behav Med 2008;31:169–77
    1. Hedman E Therapist guided internet delivered cognitive behavioural therapy. BMJ 2014;348:g1977.
    1. Andersson E, Enander J, Andren P, et al. . Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial. Psychol Med 2012;42:2193–203
    1. Hedman E, Ljotsson B, Lindefors N. Cognitive behavior therapy via the Internet: a systematic review of applications, clinical efficacy and cost-effectiveness. Expert Rev Pharmacoecon Outcomes Res 2012;12:745–64
    1. Wootton BM, Dear BF, Johnston L, et al. . Remote treatment of obsessive-compulsive disorder: a randomized controlled trial. J Obsessive Compuls Relat Disord 2013;2:375–84
    1. Andersson G Using the Internet to provide cognitive behaviour therapy. Behav Res Ther 2009;47:175–80
    1. Mayo-Wilson E, Montgomery P. Media-delivered cognitive behavioural therapy and behavioural therapy (self-help) for anxiety disorders in adults. Cochrane Database Syst Rev 2013;9:CD005330.
    1. Berger T, Hammerli K, Gubser N, et al. . Internet-based treatment of depression: a randomized controlled trial comparing guided with unguided self-help. Cogn Behav Ther 2011;40:251–66
    1. Kenwright M, Marks I, Graham C, et al. . Brief scheduled phone support from a clinician to enhance computer-aided self-help for obsessive-compulsive disorder: randomized controlled trial. J Clin Psychol 2005;61:1499–508
    1. Andersson G, Cuijpers P, Carlbring P, et al. . Internet-based vs. face-to-face cognitive behaviour therapy for psychiatric and somatic disorders: a systematic review and meta-analysis. World Psychiatry In press, 2013
    1. Hedman E, Ljotsson B, Kaldo V, et al. . Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care. J Affect Disord 2014;155:49–58
    1. Ruwaard J, Lange A, Schrieken B, et al. . The effectiveness of online cognitive behavioral treatment in routine clinical practice. PLoS ONE 2012;7:e40089.
    1. Williams AD, Andrews G. The effectiveness of Internet cognitive behavioural therapy (iCBT) for depression in primary care: a quality assurance study. PLoS ONE 2013;8:e57447.
    1. Svanborg P, Åsberg M. A new self-rating scale for depression and anxiety states based on the comprehensive psychopathological rating scale. Acta Psychiatr Scand 1994;89:21–8
    1. Saunders JB, Aasland OG, Babor TF, et al. . Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption. Addiction 1993;88:791–804
    1. Berman AH, Bergman H, Palmstierna T, et al. . Evaluation of the Drug Use Disorders Identification Test (DUDIT) in criminal justice and detoxification settings and in a Swedish population sample. Eur Addict Res 2005;11:22–31
    1. Oosthuizen P, Lambert T, Castle DJ. Dysmorphic concern: prevalence and associations with clinical variables. Aust N Z J Psychiatry 1998;32:129–32
    1. LeBeau RT, Mischel ER, Simpson HB, et al. . Preliminary assessment of obsessive–compulsive spectrum disorder scales for DSM-5. J Obsessive Compuls Relat Disord 2013;2:114–18
    1. Sheehan DV, Lecrubier Y, Sheehan KH, et al. . The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998;59(Suppl 20):22–33
    1. Phillips KA The broken mirror: understanding and treating body dysmorphic disorder. Revised and expanded edition. New York: Oxford University Press, 2005
    1. First MB, Gibbon M, Spitzer RL, et al. . Structured clinical interview for DSM-IV axis I disorders (SCID-I) (Swedish Version). Danderyd: Pilgrim Press, 1999
    1. Coles ME, Cook LM, Blake TR. Assessing obsessive compulsive symptoms and cognitions on the internet: evidence for the comparability of paper and Internet administration. Behav Res Ther 2007;45:2232–40
    1. Carlbring P, Brunt S, Bohman S, et al. . Internet vs. paper and pencil administration of questionnaires commonly used in panic/agoraphobia research. Comput Human Behav 2007;23:1421–34
    1. Enander J, Andersson E, Kaldo V, et al. . Internet administration of the dimensional obsessive-compulsive scale: a psychometric evaluation. J Obsessive Compuls Relat Disord 2012;1:325–30
    1. Phillips KA, Hollander E, Rasmussen SA, et al. . A severity rating scale for body dysmorphic disorder: development, reliability, and validity of a modified version of the Yale-Brown Obsessive Compulsive Scale. Psychopharmacol Bull 1997;33:17–22
    1. Phillips KA, Hart AS, Menard W. Psychometric evaluation of the Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS). J Obsessive Compuls Relat Disord 2014;3:205–8
    1. Guy W, ed. Clinical global impressions. Rockville: US Department of Health and Human services, 1976
    1. Zaider TI, Heimberg RG, Fresco DM, et al. . Evaluation of the clinical global impression scale among individuals with social anxiety disorder. Psychol Med 2003;33:611–22
    1. Kadouri A, Corruble E, Falissard B. The improved Clinical Global Impression Scale (iCGI): development and validation in depression. BMC Psychiatry 2007;7:7.
    1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders: DSM-IV-TR. 4th edn Washington, DC: American Psychiatric Association, 2000
    1. Aas IH Global assessment of functioning (GAF): properties and frontier of current knowledge. Ann Gen Psychiatry 2010;9:20.
    1. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382–9
    1. Svanborg P, Asberg M. A comparison between the Beck Depression Inventory (BDI) and the self-rating version of the Montgomery Asberg Depression Rating Scale (MADRS). J Affect Disord 2001;64:203–16
    1. Snorrason I, Ólafsson RP, Flessner CA, et al. . The skin picking scale-revised: factor structure and psychometric properties. J Obsessive Compuls Relat Disord 2012;1:133–7
    1. Cash TF, Fleming EC. The impact of body-image experiences: development of the body image quality of life inventory. Int J Eat Disord 2002;31:455–46
    1. Cash TF, Jakatdar TA, Williams EF. The body image quality of life inventory: further validation with college men and women. Body Image 2004;1:279–87
    1. Rozental A, Andersson G, Boettcher J, et al. . Consensus statement on defining and measuring negative effects of Internet interventions. Internet Interv 2014;1:12–19
    1. Andersson E, Ljotsson B, Hedman E, et al. . Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot study. BMC Psychiatry 2011;11:125.
    1. Royston P Multiple imputation of missing values: further update of ice, with an emphasis on interval censoring. Stata J 2007;7:445–64
    1. Rubin DB, Schenker N. Multiple imputation in health-care databases: an overview and some applications. Stat Med 1991;10:585–98
    1. Barnard RJ, Rubin DB. Miscellanea. Small-sample degrees of freedom with multiple imputation. Biometrika 1999;86:948–55
    1. Borenstein M, Hedges LV, Higgins JPT, et al. . Introduction to meta-analysis. Chichester, UK: Wiley, 2009
    1. Stata Statistical Software: Release 13 [program]. College Station, TX: StataCorp LP, 2013
    1. Mataix-Cols D, Cameron R, Gega L, et al. . Effect of referral source on outcome with cognitive-behavior therapy self-help. Compr Psychiatry 2006;47:241–5
    1. Waller G Evidence-based treatment and therapist drift. Behav Res Ther 2009;47:119–27
    1. Ljótsson B, Hesser H, Andersson E, et al. . Provoking symptoms to relieve symptoms: a randomized controlled dismantling study of exposure therapy in irritable bowel syndrome. Behav Res Ther 2014;55:27–39
    1. Phillips KA, Pagano ME, Menard W, et al. . A 12-month follow-up study of the course of body dysmorphic disorder. Am J Psychiatry 2006;163:907–12
    1. Eisen JL, Phillips KA, Baer L, et al. . The brown assessment of beliefs scale: reliability and validity. Am J Psychiatry 1998;155:102–8

Source: PubMed

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