Vaginal repair of cystocele with anterior wall mesh via transobturator route: efficacy and complications with up to 3-year followup

Robert D Moore, John R Miklos, Robert D Moore, John R Miklos

Abstract

Study objective: The objective of this study was to report on the safety and efficacy of cystocele repair with anterior wall mesh placed via a transobturator route (Perigee system, AMS, Minnetonka, MN).

Design: Single center retrospective study.

Setting: Single center hospital setting and Urogynecology practice in the United States.

Patients: 77 women presenting with symptomatic anterior wall prolapse.

Intervention: Repair of cystocele with an anterior wall Type I soft-polypropylene mesh placed via a transobturator approach. Concomitant procedures in other compartment were also completed as indicated.

Measurements and main results: 77 women underwent the Perigee procedure at our institution over a 2-year period. The mesh was attached to the pelvic sidewalls at the level of the bladder neck and near the ischial spine apically with needles passed through the groins and obturator space. Mean follow-up was 18.2 months (range 3-36 months). Objective cure rate was 93%. Subjectively only two patients have had recurrent symptoms of prolapse, and only 1 of these has required repeat surgery for cystocele. Mesh exposure vaginally occurred in 5 patients (6.5%); however all were treated with estrogen and/or local excision of exposed mesh and had no further sequelae. There were no incidences of chronic pain, infection, or abscess, and no patient required complete mesh removal for infection, pain, or extrusion.

Conclusion: In select patients with anterior wall prolapse, repair with mesh augmentation via the transobturator route is a safe and effective procedure with up to 3 years of follow-up.

Figures

Figure 1
Figure 1
Inferior or “apical” needle being passed through the obturator space to attach the more apical arm of the mesh graft to the pelvic sidewall at the level of the ischial spine.
Figure 2
Figure 2
Final positioning of the mesh providing support under the bladder.

References

    1. Beer M, Kuhn A. Surgical techniques for vault prolapse: a review of the literature. European Journal of Obstetrics Gynecology & Reproductive Biology. 2005;119(2):144–155.
    1. Olsen AL, Smith VJ, Bergstrom JO, et al. Epidemiology of surgically managed pelvic organ prolapse and urinary incontinence. Obstetrics & Gynecology. 1997;8(5):501–506.
    1. Maher C, Baessler K. Surgical management of anterior vaginal wall prolapse: an evidence based literature review. International Urogynecology Journal and Pelvic Floor Dysfunction. 2006;17(2):195–201.
    1. Nygaard IE, McCreery R, Brubaker L. Abdominal sacrocolpopexy: a comprehensive review. Obstetrics and Gynecology. 2004;104(4):805–823.
    1. Julian TM. The efficacy of marlex mesh in the repair of severe, recurrent vaginal prolapse of the anterior midvaginal wall. American Journal of Obstetrics & Gynecology. 1996;175:1472–1475.
    1. Nicita G. A new operation for genitourinary prolapse. The Journal of Urology. 1998;160(3):741–745.
    1. Flood CG, Drutz HP, Waja L. Anterior colporraphy reinforced with mrlex mesh for the treatment of cystoceles. International Urogynecology Journal. 1998;9:200–204.
    1. Mage P. Interposition of a synthetic mesh by vaginal approach in the cure of genital prolapse. Journal Gynecology Obstetrics Biology Reproduction. 1999;28(8):825–829.
    1. Migliari R, De Angelis M, Madeddu G, Verdacchi T. Tension-free vaginal mesh repair for anterior vaginal wall prolapse. European Urology. 2000;38:151–155.
    1. Hardiman P, Oyawoye S, Browning J. Cystocele repair using polypropylene mesh. British Journal Obstetrics Gynaecology. 2000;107:825–826.
    1. Adhoute F, Soyeur L, Pariente JL, Le Guillou M, Ferriere JM. Use of transvaginal polypropylene mesh (GyneMesh) for the treatment of pelvic floor disorders in women. Prospective study in 52 patients (in French with English abstract) Program Urology. 2004;14(2):192–196.
    1. Shah DK, Paul EM, Rastinehad AR, Eisenberg ER, Baldani GH. Short-term outcome analysis of total pelvis reconstruction with mesh: the vaginal approach. The Journal of Urology. 2004;171(1):261–263.
    1. Dwyer PL, O'Reilly BA. Transvaginal repair of anterior and posterior compartment prolapse with atrium polypropylene mesh. British Journal of Obstetrics and Gynaecology. 2004;111(8):831–836.
    1. Milani R, Salvatore S, Soligo M, Pifarotti P, Meschia M, Cortese M. Functional and anatomical outcome of anterior and posterior vaginal prolapse repair with prolene mesh. British Journal of Obstetrics and Gynaecology. 2004;111(1):1–5.
    1. de Tayrac R, Deffieux X, Gervaise A, Chauveaud A, Fernandez H. Long-term anatomical and functional assessment of transvaginal cystocele repair using a tension-free polypropylene mesh. International Urogynecology Journal and Pelvic Floor Dysfunction. 2006;17(5):483–488.
    1. de Tayrac R, Devoldere G, Renaudie J, Villard P, Guilbaud O, Eglin G. Prolapse repair by vaginal route using a new protected low-weight polypropylene mesh: 1-year functional and anatomical outcome in a prospective multicentre study. International Urogynecology Journal. 2007;18(3):251–256.
    1. Hiltunen R, Nieminen K, Takala T, et al. Low-weight polypropylene mesh for anterior vaginal wall prolapse. Obstetrics and Gynecology. 2007;110:455–462.
    1. Sivaslioglu AA, Unlubilgin E, Dolen I. A randomized comparison of polypropylene mesh surgery with site-specific surgery in the treatment of cystocoele. International Urogynecology Journal. 2008;19(4):467–471.
    1. Nieminen K, Hiltunen R, Heiskanen E, et al. Symptom resolution and sexual function after anterior vaginal wall repair with or without polypropylene mesh. International Urogynecology Journal. 2008;19(12):1611–1616.
    1. Mellier G, Benayed B, Bretones S, Pasquier JC. Suburethral tape via the obturator route: is the TOT a simplification of the TVT? International Urogynecology Journal and Pelvic Floor Dysfunction. 2004;15(4):227–232.
    1. Davila GW, Johnson JD, Serels S. Multicenter experience with the Monarc transobturator sling system to treat stress urinary incontinence. International Urogynecology Journal and Pelvic Floor Dysfunction. 2006;17(5):460–465.
    1. Achtari C, McKenzie BJ, Hiscock R, et al. Anatomical study of the obturator foramen and dorsal nerve of the clitoris and their relationship to minimally invasive slings. International Urogynecology Journal and Pelvic Floor Dysfunction. 2006;17(4):330–334.
    1. Richardson AC, Lyon JB, Williams NL. A new look at pelvic relaxation. American Journal of Obstetrics and Gynecology. 1697;126(5):568–573.
    1. Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S. Surgical management of pelvic organ prolapse in women. Cochrane Database System Review. 2007;18(3) Article ID CD004014.
    1. Misrai V, Almeras C, Roupret M, et al. Laparoscopic repair of urogenital prolapse without paravaginal repair: medium-term anatomical results. Progres en Urologie. 2007;17(4):846–849.
    1. Paraiso MF, Menafee S, Schaffer J, Varner E, Fitzgerald MP. Investigation of surgical procedures for pelvic organ prolapse-the mesh dilemma. Journal of Minimally Invasive Gynecology. 2008;15(5):521–522.
    1. Ridgeway B, Walters MD, Paraiso MFR, et al. Early experience with mesh excision for adverse outcomes after transvaginal mesh placement using prolapse kits. American Journal of Obstetrics and Gynecology. 2008;199(6):703.e1–703.e7.
    1. Marguilies R, Lewicky-Gaupp C, Fenner D, McGuire E, Clemens Q, Delancey J. Complications requiring re-operation following vaginal mesh kit procedures for prolapse. American Journal of Obstetrics and Gynecology. 2008;199(6):678.e1–678.e4.
    1. Gauruder-Burmester A, Koutouzidou P, Rohne J, Gronewold M, Tunn R. Follow-up after polypropylene mesh repair of anterior and posterior compartments in patients with recurrent prolapse. International Urogynecology Journal and Pelvic Floor Dysfunction. 2007;18(9):1059–1064.
    1. Nguyen JN, Burchette RJ. Outcome after anterior vaginal prolapse repair: a randomized controlled trial. Obstetrics and Gynecology. 2008;111(4):891–898.
    1. Fatton B, Amblard J, Debodinance P, Cosson M, Jacquetin B. Transvaginal repair of genital prolapse: preliminary results of a new tension-free vaginal mesh (Prolift system)-a case series multicentric study. International Urogynecology Journal. 2007;18(7):743–752.
    1. Boyles S, McCrery R. Dyspareunia and mesh erosion after vaginal mesh placement with a kit procedure. Obstetrics and Gynecology. 2008;111(4):969–975.
    1. Lowman J, Jones L, Woodman P, Hale D. Does the prolift system cause dyspareunia? American Journal of Obstetrics and Gynecology. 2008;199(6):707.e1–707.e6.
    1. Sentilhes L, Berthier A, Sergent F, Verspyck E, Descamps P, Marpeau L. Sexual function in women before and after transvaginal mesh placement for pelvic organ prolapse. International Urogynecology Journal and Pelvic Floor Dysfunction. 2008;19(6):763–772.
    1. Gauruder-Burmester A, Koutouzidou P, Tunn R. Effect of vaginal polypropylene mesh implants on sexual function. European Journal of Obstetrics Gynecology & Reproductive Biology. 2009;142(1):76–80.
    1. Nieminen K, Hiltunen R, Heiskanen E, et al. Symptom resolution and sexual function after anterior vaginal wall repair with or without polypropylene mesh. International Urogynecology Journal and Pelvic Floor Dysfunction. 2008;19(12):1611–1616.

Source: PubMed

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