STS-ACC TVT Registry of Transcatheter Aortic Valve Replacement

Abstract

The STS-ACC TVT Registry (Society of Thoracic Surgeons-American College of Cardiology Transcatheter Valve Therapy Registry) from 2011 to 2019 has collected data on 276,316 patients undergoing transcatheter aortic valve replacement (TAVR) at sites in all U.S. states. Volumes have increased every year, exceeding surgical aortic valve replacement in 2019 (72,991 vs. 57,626), and it is now performed in all U.S. states. TAVR now extends from extreme- to low-risk patients. This is the first presentation on 8,395 low-risk patients treated in 2019. In 2019, for the entire cohort, femoral access increased to 95.3%, hospital stay was 2 days, and 90.3% were discharged home. Since 2011, the 30-day mortality rate has decreased (7.2% to 2.5%), stroke has started to decrease (2.75% to 2.3%), but pacemaker need is unchanged (10.9% to 10.8%). Alive with acceptable patient-reported outcomes is achieved in 8 of 10 patients at 1 year. The Registry is a national resource to improve care and analyze TAVR's evolution. Real-world outcomes, site performance, and the impact of coronavirus disease 2019 will be subsequently studied. (STS/ACC Transcatheter Valve Therapy Registry [TVT Registry]; NCT01737528).

Keywords: TAVR; aortic stenosis; outcomes; registry; valvular heart disease.

Conflict of interest statement

Author Relationship With Industry Dr. Carroll has been a local investigator for clinical trials sponsored by Edwards Lifesciences, Medtronic, and Abbott; and has been a consultant to Abbott. Dr. Mack has had nonremunerative positions of clinical trial leadership at Edwards Lifesciences, Medtronic, and Abbott. Dr. Vemulapalli has received grants/contracts from the American College of Cardiology, Society of Thoracic Surgeons, National Institutes of Health, Patient Centered Outcomes Research Institute, Food and Drug Administration (NESTcc), Boston Scientific, and Abbott Vascular; and has been a consultant/Advisory Board member for Boston Scientific, Janssen, and HeartFlow. Dr. Herrmann has received institutional research grants from Abbott Vascular, Bayer, Boston Scientific, Edwards Lifesciences, and Medtronic; and has received consulting fees from Abbott Vascular, Edwards Lifesciences, and Medtronic. Dr. Gleason has been a member of the Medical Advisory Board for Abbott. Dr. Hanzel has been the local site principal investigator for trials sponsored by Edwards Lifesciences, Abbott, and Boston Scientific. Dr. Deeb has been the local site principal investigator in the Medtronic International TAVR clinical trials. Dr. Thourani has been an advisor to or received research grants from Abbott Vascular, Boston Scientific, Edwards Lifesciences, Gore Vascular, and JenaValve. Dr. Cohen has received research grant support from Edwards Lifesciences, Medtronic, Boston Scientific, and Abbott; and has received consulting income from Edwards Lifesciences, Medtronic, Boston Scientific, and Abbott. Dr. Desai has been an advisor to or received research grants from Gore, Medtronic, and Terumo. Dr. Kirtane has received institutional funding to Columbia University and/or Cardiovascular Research Foundation from Medtronic, Boston Scientific, Abbott Vascular, Abiomed, CSI, CathWorks, Siemens, Philips, and ReCor Medical (in addition to research grants, institutional funding includes fees paid to Columbia University and/or Cardiovascular Research Foundation for speaking engagements and/or consulting); and has received travel expenses/meals from Medtronic, Boston Scientific, Abbott Vascular, Abiomed, CSI, CathWorks, Siemens, Philips, ReCor Medical, Chiesi, OpSens, Zoll, and Regeneron. Dr. Masoudi has had a contract with the American College of Cardiology for his role as chief scientific advisor, NCDR. Dr. Brindis is senior medical officer, EXTERNAL AFFAirs–ACC National Cardiovascular Data Registry. Dr. Bavaria has been a local investigator for TAVR clinical trials sponsored by Edwards Lifesciences, Medtronic, Abbott, and Boston Scientific; and has been a consultant to Edwards Lifesciences and Abbott. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Copyright © 2020 Society of Thoracic Surgeons and the American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.