With haemoglobin as with politics - should we shift right or left?

Jerome A Dempsey, Jerome A Dempsey

No abstract available

Keywords: O2 transport; high altitude hypoxia; high vs low HbO2 affinity.

References

    1. Barcroft J, Binger CA, Bock AV, Doggart JH, Forbes HS, Harrup G, Meakins JC, Redfield AC, Davies HW, Duncan Scott JM, Fetter WJ, Murray CD & Keith A (1923). Observations upon the effect of high altitude on the physiological process of the human body carried out in the Peruvian Andes, chiefly at Cerro de Pasco. Philos Trans R Soc Lond B Biol Sci 211, 351-480.
    1. Dominelli PB, Wiggins CC, Baker SE, Shepherd JRA, Roberts SK, Roy TK, Curry TB, Hoyer JD, Oliveira JL & Joyner MJ (2020). Influence of high affinity hemoglobin on the response to normoxic and hypoxic exercise. J Physiol 598, 1475-1490.
    1. Storz JF (2016). Hemoglobin-oxygen affinity in high altitude vertebrates: Is there evidence for an adaptive trend? J Exp Biol 219, 3190-3203.
    1. Winslow RP (2007). Role of hemoglobin-oxygen affinity in O2 transport at high altitude. Respir Physiol Neurobiol 158, 121-127.
    1. Woodson R & Auerbach S (1982). Effect of increased HbO2 affinity and anemia on cardiac output and its distribution. J Appl Physiol 53, 1299-1306.

Source: PubMed

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구독하다