- ICH GCP
- US Clinical Trials Registry
- Klinisk utprøving NCT02484612
Exercise Intensity and Appetite in Adolescents
Effect of Acute Exercise Intensity on Energy Intake in Adolescents: Effect of Weight Status
Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings.
Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults.
The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.
Studieoversikt
Detaljert beskrivelse
After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:
- anthropometric measurements
- Body composition assessed by dual energy x-ray absorptiometry
- Maximal aerobic test
They will then randomly complete the following conditions:
- CON: a control day without exercise;
- HIE: an exercise day with an exercise set at 75% of the capacities
- LIE: an exercise day with an exercise set at 40% of the capacities
The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted.
Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.
Studietype
Registrering (Forventet)
Fase
- Ikke aktuelt
Deltakelseskriterier
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
Tar imot friske frivillige
Kjønn som er kvalifisert for studier
Beskrivelse
Inclusion Criteria:
- 12 to 15 years old adolescents
- Obese according to international values for BMI
- Being registered to the national social security insurance
- no eating disorders
- no medications
- metabolic disorders
Exclusion Criteria:
- metabolic disorders
- food disorders
- physical disability
Studieplan
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Grunnvitenskap
- Tildeling: Randomisert
- Intervensjonsmodell: Faktoriell oppgave
- Masking: Ingen (Open Label)
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
|
Eksperimentell: Lean adolescents
15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited
|
|
|
Eksperimentell: Obese adolescents
15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
energy intake in kcal
Tidsramme: up to 2 months
|
buffet meal
|
up to 2 months
|
Samarbeidspartnere og etterforskere
Studierekorddatoer
Studer hoveddatoer
Studiestart
Primær fullføring (Forventet)
Studiet fullført (Forventet)
Datoer for studieregistrering
Først innsendt
Først innsendt som oppfylte QC-kriteriene
Først lagt ut (Anslag)
Oppdateringer av studieposter
Sist oppdatering lagt ut (Anslag)
Siste oppdatering sendt inn som oppfylte QC-kriteriene
Sist bekreftet
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- AME2P Laboratory
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