Exercise Intensity and Appetite in Adolescents

May 10, 2016 updated by: THIVEL David, Université Blaise Pascal, Clermont-Ferrand

Effect of Acute Exercise Intensity on Energy Intake in Adolescents: Effect of Weight Status

Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings.

Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults.

The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations:

  • anthropometric measurements
  • Body composition assessed by dual energy x-ray absorptiometry
  • Maximal aerobic test

They will then randomly complete the following conditions:

  • CON: a control day without exercise;
  • HIE: an exercise day with an exercise set at 75% of the capacities
  • LIE: an exercise day with an exercise set at 40% of the capacities

The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted.

Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

Study Type

Interventional

Enrollment (Anticipated)

30

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

12 years to 15 years (Child)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders

Exclusion Criteria:

  • metabolic disorders
  • food disorders
  • physical disability

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Factorial Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Lean adolescents
15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited
Behavioral: acute exercise
Experimental: Obese adolescents
15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited
Behavioral: acute exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
energy intake in kcal
Time Frame: up to 2 months
buffet meal
up to 2 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Université Blaise Pascal, Clermont-Ferrand

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2016

Primary Completion (Anticipated)

December 1, 2017

Study Completion (Anticipated)

December 1, 2017

Study Registration Dates

First Submitted

June 19, 2015

First Submitted That Met QC Criteria

June 25, 2015

First Posted (Estimate)

June 29, 2015

Study Record Updates

Last Update Posted (Estimate)

May 11, 2016

Last Update Submitted That Met QC Criteria

May 10, 2016

Last Verified

May 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • AME2P Laboratory

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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