- ICH GCP
- US Clinical Trials Registry
- Klinisk utprøving NCT07656480
The Effects of Single Baduanjin and Elastic Band Exercises on VSWM in Elderly Individuals With MCI
The Effects of Single Baduanjin and Elastic Band Exercises on Visuospatial Working Memory in Elderly Individuals With Mild Cognitive Impairment
Studieoversikt
Status
Forhold
Intervensjon / Behandling
Studietype
Registrering (Antatt)
Fase
- Ikke aktuelt
Kontakter og plasseringer
Studiekontakt
- Navn: chen qiu
- Telefonnummer: 86+13964805297
- E-post: q13964805297@163.com
Deltakelseskriterier
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
- Eldre voksen
Tar imot friske frivillige
Beskrivelse
Inclusion Criteria:
- Include the elderly population aged between 60 and 74 years old.
- Includes individuals with cognitive impairments. The patients or informants report experiencing memory decline and having certain cognitive dysfunction (MoCA score = 18-25 points).
- Including individuals who have controlled diabetes and/or cardiovascular diseases to a stable state.
- Irregular exercise with the ability to complete a certain amount of physical activities.
- Normal vision and hearing.
Exclusion Criteria:
- Patients with moderate to severe cognitive impairment, mental illness or other neurodegenerative diseases (such as Parkinson's dementia, stroke, frontotemporal degeneration, vascular dementia, Lewy body dementia, etc.).
- Long-term or recent use of psychotropic drugs, drugs that affect physical activity ability, cholinergic inhibitors, etc.
- Regular exercise habit .
- There are serious muscle disorders, or there has been an injury to the lower limbs within the previous six months, making it impossible to stand for a long time or to stand at all.
- Severe cardiovascular disease.
Studieplan
Hvordan er studiet utformet?
Designdetaljer
- Primært formål: Behandling
- Tildeling: Randomisert
- Intervensjonsmodell: Parallell tildeling
- Masking: Enkelt
Våpen og intervensjoner
Deltakergruppe / Arm |
Intervensjon / Behandling |
|---|---|
|
Ingen inngripen: styre
|
|
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Eksperimentell: baduanjin
|
Perform the 30-minute Baduanjin exercise
|
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Eksperimentell: Resistance band
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Perform 30 minutes of elastic band exercises
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Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
visuo-spatial working memory
Tidsramme: From July 1, 2026, to September 1, 2026, the duration is two months.
|
The primary research outcome pertains to visuospatial working memory, which is measured through a visuospatial working memory task paradigm.
The specific paradigm is as follows: First, a "+" appears in the middle of a gray computer screen for 300 ms.
Second, a 4x4 grid matrix appears at the center of the screen for 2000 ms, with 5 small black squares randomly placed within the matrix.
Immediately afterwards, a blank screen is presented for 3000 ms.
During this period, the participants are required to mentally visualize the probe stimulus after rotating it 90° to the left (or right).
Subsequently, a 4x4 grid target stimulus is presented again for 4000 ms, and the participants need to make a judgment on the target stimulus, specifically whether it is the result of rotating the probe stimulus 90° to the left (or right), as shown in Figure 3.
The entire experiment lasts approximately 8 minutes.
|
From July 1, 2026, to September 1, 2026, the duration is two months.
|
Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
|---|---|---|
|
EEG power value
Tidsramme: The total duration was two months.
|
The testers adjusted the impedance to below 5kΩ and followed the 26-system electrode placement method specified by the International Federation of Electroencephalography.
They set Fp1, Fp2, F3, F4, F7, F8, Fc3, Fc4, C3, C4, Cp3, Cp4, P3, P4, Pz, O1, O2, Oz, Po3, Po4, T3, T4, T5, and T6 leads.
The ground electrode was set as GND, and the reference electrode was at the bilateral earlobe positions of A1 and A2.
After stabilization, they began to record the EEG signals for 5 minutes.
Using the toolbox, they filtered out data segments with obvious artifact interference.
They analyzed the EEG indicators, including frontal cortex δ-β2 (Fp1, Fp2, F3, F4, F7, F8, AF3, AF4, Fc3, Fc4), central cortex δ-β2 (C3, C4, Cp3, Cp4), parietal cortex δ-β2 (P3, P4, Pz), occipital cortex δ-β2 (O1, O2, Oz, Po3, Po4), and temporal cortex δ-β2 (T3, T4, T5, T6).
|
The total duration was two months.
|
Samarbeidspartnere og etterforskere
Sponsor
Studierekorddatoer
Studer hoveddatoer
Studiestart (Antatt)
Primær fullføring (Antatt)
Studiet fullført (Antatt)
Datoer for studieregistrering
Først innsendt
Først innsendt som oppfylte QC-kriteriene
Først lagt ut (Faktiske)
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
Siste oppdatering sendt inn som oppfylte QC-kriteriene
Sist bekreftet
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- 183551747
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