- ICH GCP
- US Clinical Trials Registry
- Klinisk utprøving NCT07812038
Predictive Value of Chest Trauma Score , Revised Trauma Score , and Glasgow Coma Scale in Patients Presenting With Chest Trauma at Assiut University Emergency Unit.
4. september 2026 oppdatert av: Tarek Ragaey Ali Sayed, Assiut University
Thoracic trauma is a critical clinical entity and a major global public health burden, representing the second most frequently occurring unintentional traumatic injury and the third most common cause of death-following head and abdominal injuries-in patients with polytrauma.
It places a substantial demand on emergency departments and directly accounts for 20% to 25% of all trauma-related fatalities worldwide(1).
The severity of these injuries is underscored by persistently high mortality rates, which can reach up to 60% in cases of severe blunt chest trauma depending on the healthcare setting.
Recent epidemiological data indicates that among potentially preventable trauma deaths, thoracic injuries represent up to 41%, with blunt mechanisms such as motor vehicle collisions acting as the primary driver (accounting for 80% to 92% of cases)(2).
Given this significant risk profile, rapid and accurate clinical triage is vital.
Current evidence consistently demonstrates that early recognition, protocolized multidisciplinary management, and the timely provision of definitive interventions at dedicated trauma centers are essential to decreasing morbidity and significantly reducing preventable trauma mortality(3).Effective initial assessment in the ED relies heavily on validated trauma scoring systems.
GCS is the most universally utilized tool for evaluating a patient's level of consciousness, calculating a score between 3 and 15 based on three physiological parameters: eye opening, verbal response, and motor response.
RTS is a broader physiological scoring system combining the GCS, systolic blood pressure, and respiratory rate.
CTS is a specific, targeted assessment tool designed to quantify the severity of thoracic injuries.
Studieoversikt
Status
Har ikke rekruttert ennå
Forhold
Studietype
Observasjonsmessig
Registrering (Antatt)
100
Deltakelseskriterier
Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
- Eldre voksen
Tar imot friske frivillige
Nei
Prøvetakingsmetode
Sannsynlighetsprøve
Studiepopulasjon
Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST).
Beskrivelse
Inclusion Criteria:
- Age threshold: Patients aged 18 years and older (pediatric physiology requires entirely different trauma scoring systems).
- Mechanism of injury: Patients presenting with acute blunt or penetrating thoracic trauma or both.
- Diagnostic confirmation: Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST).
- Time of presentation: Patients presenting directly to the emergency department within 24 hours of the trauma incident.
Exclusion Criteria:
- Inter-facility transfers: Exclude patients transferred from other hospitals. If they were already intubated, given sedatives, or resuscitated elsewhere, their admission scores will be artificially altered and will not reflect their true initial presentation.
- Dead on Arrival (DOA): Patients who arrive in cardiac arrest or expire before the initial primary survey and scoring can be completed.
- Isolated severe head trauma or massive burns: Patients whose clinical picture and need for intubation are overwhelmingly driven by severe traumatic brain injury (e.g., GCS < 8 from head injury alone without significant chest trauma) or massive burns, rather than the thoracic injury.
- Severe chronic cardiopulmonary disease: patients with known end-stage COPD, severe baseline heart failure, or those on home oxygen. Their baseline hypoxia or need for ventilation can confound the trauma scores' predictive value.
- Incomplete data: Patients whose medical records are missing the crucial variables needed to calculate the GCS, RTS, or CTS upon arrival.
Studieplan
Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.
Hvordan er studiet utformet?
Designdetaljer
Kohorter og intervensjoner
Gruppe / Kohort |
|---|
|
study group
Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST
|
Hva måler studien?
Primære resultatmål
Resultatmål |
Tidsramme |
|---|---|
|
diagnositic acuracy of the Glasgow Coma Scale (GCS), in cases of thoracic trauma.
Tidsramme: baseline
|
baseline
|
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diagnostic acuracy of the Revised Trauma Score (RTS) in cases of thoracic trauma.
Tidsramme: baseline
|
baseline
|
|
diagnostic acuracy of the Chest Trauma Score (CTS) in cases of thoracic trauma.
Tidsramme: baseline
|
baseline
|
Samarbeidspartnere og etterforskere
Det er her du vil finne personer og organisasjoner som er involvert i denne studien.
Sponsor
Studierekorddatoer
Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.
Studer hoveddatoer
Studiestart (Antatt)
1. oktober 2026
Primær fullføring (Antatt)
1. oktober 2027
Studiet fullført (Antatt)
1. desember 2027
Datoer for studieregistrering
Først innsendt
4. september 2026
Først innsendt som oppfylte QC-kriteriene
4. september 2026
Først lagt ut (Faktiske)
10. september 2026
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
10. september 2026
Siste oppdatering sendt inn som oppfylte QC-kriteriene
4. september 2026
Sist bekreftet
1. september 2026
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- CTS ,RTS& GCS
Legemiddel- og utstyrsinformasjon, studiedokumenter
Studerer et amerikansk FDA-regulert medikamentprodukt
Nei
Studerer et amerikansk FDA-regulert enhetsprodukt
Nei
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