Correlation Of EUS-SWQ And Liver Fibrosis Pathology In Chronic Liver Disease (EUS-SWQ-202601)

Inclusion Criteria:

1. Age ≥ 18 years and ≤ 80 years.
2. Patients with clinical indications scheduled to undergo liver biopsy (EUS-guided) for the evaluation of liver lesions. Chronic liver disease meeting criteria for biopsy includes:Hepatitis B；Fatty liver disease；Autoimmune hepatitis；Other chronic liver diseases of unknown etiology that would benefit from liver biopsy
3. Planned to undergo EUS-SWQ and FibroScan examinations prior to biopsy.
4. Willing to provide and sign written informed consent.

Exclusion Criteria:

1. Patients unable to tolerate endoscopic procedures.
2. Patients with contraindications to endoscopy or anesthesia.
3. Coagulopathy (platelet count < 50×10⁹/L, PT > upper limit of normal by 3 seconds).
4. Patients with severe underlying diseases of the respiratory, cardiovascular, cerebrovascular, digestive, or hematologic systems, as well as those with psychiatric disorders.
5. Patients with surgically altered anatomy that precludes adequate EUS imaging of the hepatic parenchyma.
6. Patients with imaging findings suggestive of malignant liver tumors.
7. Pregnant or lactating women.
8. Patients with decompensated cirrhosis (gastrointestinal bleeding, ascites, encephalopathy).
9. Patients who refuse to participate in the clinical study.
10. Any other conditions deemed inappropriate by the investigator.