Nivolumab efter kirurgi och kemoterapi vid behandling av patienter med stadium IB-IIIA icke-småcellig lungcancer (en behandlingsförsök med ALKEMISTER) (ANVIL)
11 november 2026 uppdaterad av: National Cancer Institute (NCI)
Adjuvant Nivolumab vid resekerad lungcancer (ANVIL) - En randomiserad fas III-studie av Nivolumab efter kirurgisk resektion och adjuvant kemoterapi vid icke-småcellig lungcancer
This phase III ALCHEMIST treatment trial studies how well nivolumab after surgery and chemotherapy work in treating patients with stage IB-IIIA non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Studieöversikt
Status
Aktiv, inte rekryterande
Betingelser
Detaljerad beskrivning
PRIMARY OBJECTIVES:
I. To evaluate whether adjuvant therapy with nivolumab will result in improved disease-free survival (DFS) over standard observation in patients with stage IB >= 4 cm, II and IIIA, non-small cell lung cancer (NSCLC) following surgical resection and standard adjuvant therapy.
II. To evaluate whether adjuvant therapy with nivolumab will result in improved disease-free survival (DFS) over standard observation in patients with stage IB >= 4cm, II and IIIA, NSCLC with high PD-L1 expression (>= 50% staining) following surgical resection and standard adjuvant therapy.
III. To evaluate whether adjuvant therapy with nivolumab will result in improved overall survival (OS) over standard observation in patients with stage IB >= 4cm, II and IIIA, NSCLC following surgical resection and standard adjuvant therapy.
SECONDARY OBJECTIVES:
I. To evaluate the safety profile of nivolumab when given as an adjuvant therapy.
II. To evaluate and compare disease free and overall survival in patients with tumors that express PD-L1 in various patterns associated with nivolumab and standard observation.
III. To evaluate and compare disease free and overall survival in patients with tumors that have high mutational load associated with nivolumab and standard observation.
IV. To evaluate OS and DFS by stage. V. To evaluate OS and DFS by each stratification factor.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive nivolumab intravenously (IV) over 30 minutes on day 1 of each cycle. Cycles repeat every 4 weeks for up to 1 year in the absence of disease progression or unacceptable toxicity. Patients also undergo computed tomography (CT) and/or positron emission tomography (PET)/CT throughout the trial and blood sample collection during screening and follow-up. Patients may undergo an echocardiography (ECHO) as clinically indicated on study.
ARM II: Patients are followed serially with CT and/or PET/CT imaging for up to 1 year and then during follow-up. Patients also undergo blood sample collection during screening and follow-up. Patients may undergo an ECHO as clinically indicated on study.
After completion of study treatment, patients are followed up at 6 weeks, every 3 months for 2 years, every 6 months for 2 years, and then every 12 months for 6 years.
Studietyp
Interventionell
Inskrivning (Beräknad)
903
Fas
- Fas 3
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studieorter
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Alabama
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Birmingham, Alabama, Förenta staterna, 35233
- University of Alabama at Birmingham Cancer Center
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Daphne, Alabama, Förenta staterna, 36526
- Southern Cancer Center PC-Daphne
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Mobile, Alabama, Förenta staterna, 36607
- Southern Cancer Center PC-Mobile
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Mobile, Alabama, Förenta staterna, 36608
- Southern Cancer Center PC-Providence
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Mobile, Alabama, Förenta staterna, 36608
- Southern Cancer Center PC-Springhill
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Alaska
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Anchorage, Alaska, Förenta staterna, 99508
- Katmai Oncology Group
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Anchorage, Alaska, Förenta staterna, 99508
- Providence Alaska Medical Center
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Arizona
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Phoenix, Arizona, Förenta staterna, 85054
- Mayo Clinic Hospital in Arizona
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Scottsdale, Arizona, Förenta staterna, 85259
- Mayo Clinic in Arizona
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Tucson, Arizona, Förenta staterna, 85719
- Banner University Medical Center - Tucson
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Tucson, Arizona, Förenta staterna, 85719
- University of Arizona Cancer Center-North Campus
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Arkansas
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Jonesboro, Arkansas, Förenta staterna, 72401
- NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
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Little Rock, Arkansas, Förenta staterna, 72205
- John L McClellan Memorial Veterans Hospital
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California
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Anaheim, California, Förenta staterna, 92806
- Kaiser Permanente-Anaheim
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Arroyo Grande, California, Förenta staterna, 93420
- PCR Oncology
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Auburn, California, Förenta staterna, 95602
- Sutter Auburn Faith Hospital
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Auburn, California, Förenta staterna, 95603
- Sutter Cancer Centers Radiation Oncology Services-Auburn
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Bakersfield, California, Förenta staterna, 93301
- AIS Cancer Center at San Joaquin Community Hospital
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Baldwin Park, California, Förenta staterna, 91706
- Kaiser Permanente-Baldwin Park
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Bellflower, California, Förenta staterna, 90706
- Kaiser Permanente-Bellflower
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Berkeley, California, Förenta staterna, 94704
- Alta Bates Summit Medical Center-Herrick Campus
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Burlingame, California, Förenta staterna, 94010
- Mills-Peninsula Medical Center
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Cameron Park, California, Förenta staterna, 95682
- Sutter Cancer Centers Radiation Oncology Services-Cameron Park
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Carmichael, California, Förenta staterna, 95608
- Mercy San Juan Medical Center
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Castro Valley, California, Förenta staterna, 94546
- Eden Hospital Medical Center
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Clovis, California, Förenta staterna, 93611
- University Oncology Associates
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Concord, California, Förenta staterna, 94520
- John Muir Medical Center-Concord
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Corona, California, Förenta staterna, 92882
- City of Hope Corona
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Davis, California, Förenta staterna, 95616
- Sutter Davis Hospital
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Duarte, California, Förenta staterna, 91010
- City of Hope Comprehensive Cancer Center
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Elk Grove, California, Förenta staterna, 95758
- Mercy Cancer Center - Elk Grove
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Fontana, California, Förenta staterna, 92335
- Kaiser Permanente-Fontana
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Fremont, California, Förenta staterna, 94538
- Palo Alto Medical Foundation-Fremont
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Fullerton, California, Förenta staterna, 92835
- Saint Jude Medical Center
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Harbor City, California, Förenta staterna, 90710
- Kaiser Permanente South Bay
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Irvine, California, Förenta staterna, 92618
- Kaiser Permanente-Irvine
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La Jolla, California, Förenta staterna, 92093
- UC San Diego Moores Cancer Center
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Loma Linda, California, Förenta staterna, 92354
- Loma Linda University Medical Center
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Los Angeles, California, Förenta staterna, 90033
- USC / Norris Comprehensive Cancer Center
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Los Angeles, California, Förenta staterna, 90027
- Kaiser Permanente Los Angeles Medical Center
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Los Angeles, California, Förenta staterna, 90034
- Kaiser Permanente West Los Angeles
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Los Angeles, California, Förenta staterna, 90033
- Los Angeles General Medical Center
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Marysville, California, Förenta staterna, 95901
- Fremont - Rideout Cancer Center
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Modesto, California, Förenta staterna, 95355
- Memorial Medical Center
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Mountain View, California, Förenta staterna, 94040
- Palo Alto Medical Foundation-Camino Division
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Mountain View, California, Förenta staterna, 94040
- Palo Alto Medical Foundation-Gynecologic Oncology
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Novato, California, Förenta staterna, 94945
- Sutter Cancer Research Consortium
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Orange, California, Förenta staterna, 92868
- Saint Joseph Hospital - Orange
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Palm Springs, California, Förenta staterna, 92262
- Desert Regional Medical Center
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Palo Alto, California, Förenta staterna, 94304
- Stanford Cancer Institute Palo Alto
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Palo Alto, California, Förenta staterna, 94301
- Palo Alto Medical Foundation Health Care
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Panorama City, California, Förenta staterna, 91402
- Kaiser Permanente - Panorama City
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Rancho Mirage, California, Förenta staterna, 92270
- Eisenhower Medical Center
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Redding, California, Förenta staterna, 96001
- Mercy Regional Cancer Center
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Redding, California, Förenta staterna, 96002
- Mercy Oncology Center
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Riverside, California, Förenta staterna, 92505
- Kaiser Permanente-Riverside
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Rocklin, California, Förenta staterna, 95765
- Mercy Cancer Center - Rocklin
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Roseville, California, Förenta staterna, 95661
- Sutter Cancer Centers Radiation Oncology Services-Roseville
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Roseville, California, Förenta staterna, 95661
- Sutter Roseville Medical Center
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Sacramento, California, Förenta staterna, 95816
- Sutter Medical Center Sacramento
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Sacramento, California, Förenta staterna, 95817
- University of California Davis Comprehensive Cancer Center
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Sacramento, California, Förenta staterna, 95816
- Mercy Cancer Center - Sacramento
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San Diego, California, Förenta staterna, 92120
- Kaiser Permanente-San Diego Zion
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San Diego, California, Förenta staterna, 92134
- Naval Medical Center -San Diego
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San Francisco, California, Förenta staterna, 94115
- California Pacific Medical Center-Pacific Campus
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San Luis Obispo, California, Förenta staterna, 93401
- Pacific Central Coast Health Center-San Luis Obispo
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San Marcos, California, Förenta staterna, 92078
- Kaiser Permanente-San Marcos
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Santa Cruz, California, Förenta staterna, 95065
- Palo Alto Medical Foundation-Santa Cruz
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Santa Cruz, California, Förenta staterna, 95065
- Dominican Santa Cruz Hospital
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Santa Rosa, California, Förenta staterna, 95403
- Sutter Pacific Medical Foundation
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St. Helena, California, Förenta staterna, 94574
- Saint Helena Hospital
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Stockton, California, Förenta staterna, 95204
- Saint Joseph's Medical Center
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Sunnyvale, California, Förenta staterna, 94086
- Palo Alto Medical Foundation-Sunnyvale
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Truckee, California, Förenta staterna, 96161
- Gene Upshaw Memorial Tahoe Forest Cancer Center
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Vallejo, California, Förenta staterna, 94589
- Sutter Solano Medical Center/Cancer Center
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Walnut Creek, California, Förenta staterna, 94598
- John Muir Medical Center-Walnut Creek
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Woodland, California, Förenta staterna, 95695
- Woodland Memorial Hospital
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Woodland Hills, California, Förenta staterna, 91367
- Kaiser Permanente-Woodland Hills
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Colorado
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Aurora, Colorado, Förenta staterna, 80045
- UCHealth University of Colorado Hospital
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Boulder, Colorado, Förenta staterna, 80304
- Rocky Mountain Cancer Centers-Boulder
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Colorado Springs, Colorado, Förenta staterna, 80907
- Penrose-Saint Francis Healthcare
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Colorado Springs, Colorado, Förenta staterna, 80909
- UCHealth Memorial Hospital Central
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Denver, Colorado, Förenta staterna, 80205
- Kaiser Permanente-Franklin
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Denver, Colorado, Förenta staterna, 80210
- AdventHealth Porter
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Englewood, Colorado, Förenta staterna, 80113
- Mountain Blue Cancer Care Center - Swedish
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Fort Collins, Colorado, Förenta staterna, 80524
- Poudre Valley Hospital
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Golden, Colorado, Förenta staterna, 80401
- National Jewish Health-Western Hematology Oncology
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Greeley, Colorado, Förenta staterna, 80631
- Banner North Colorado Medical Center
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Lafayette, Colorado, Förenta staterna, 80026
- Kaiser Permanente-Rock Creek
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Lakewood, Colorado, Förenta staterna, 80228
- Rocky Mountain Cancer Centers-Lakewood
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Lone Tree, Colorado, Förenta staterna, 80124
- Kaiser Permanente-Lone Tree
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Loveland, Colorado, Förenta staterna, 80539
- Banner North Colorado Medical Center - Loveland Campus
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Parker, Colorado, Förenta staterna, 80138
- AdventHealth Parker
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Wheat Ridge, Colorado, Förenta staterna, 80401
- Intermountain Health Lutheran Hospital
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Connecticut
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Danbury, Connecticut, Förenta staterna, 06810
- Danbury Hospital
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Derby, Connecticut, Förenta staterna, 06418
- Smilow Cancer Hospital-Derby Care Center
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Fairfield, Connecticut, Förenta staterna, 06824
- Smilow Cancer Hospital Care Center-Fairfield
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Greenwich, Connecticut, Förenta staterna, 06830
- Greenwich Hospital
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Guilford, Connecticut, Förenta staterna, 06437
- Smilow Cancer Hospital Care Center - Guilford
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Hartford, Connecticut, Förenta staterna, 06105
- Smilow Cancer Hospital Care Center at Saint Francis
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Hartford, Connecticut, Förenta staterna, 06102
- Hartford Hospital
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Manchester, Connecticut, Förenta staterna, 06040
- Manchester Memorial Hospital
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Middletown, Connecticut, Förenta staterna, 06457
- Middlesex Hospital
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New Britain, Connecticut, Förenta staterna, 06050
- The Hospital of Central Connecticut
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New Haven, Connecticut, Förenta staterna, 06520
- Yale University
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New Haven, Connecticut, Förenta staterna, 06510
- Smilow Cancer Center/Yale-New Haven Hospital
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North Haven, Connecticut, Förenta staterna, 06473
- Yale-New Haven Hospital North Haven Medical Center
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Orange, Connecticut, Förenta staterna, 06477
- Smilow Cancer Hospital-Orange Care Center
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Stamford, Connecticut, Förenta staterna, 06904
- Stamford Hospital/Bennett Cancer Center
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Torrington, Connecticut, Förenta staterna, 06790
- Smilow Cancer Hospital-Torrington Care Center
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Trumbull, Connecticut, Förenta staterna, 06611
- Smilow Cancer Hospital Care Center-Trumbull
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Waterbury, Connecticut, Förenta staterna, 06708
- Smilow Cancer Hospital-Waterbury Care Center
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Waterford, Connecticut, Förenta staterna, 06385
- Smilow Cancer Hospital Care Center - Waterford
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West Haven, Connecticut, Förenta staterna, 06516
- Veterans Affairs Connecticut Healthcare System-West Haven Campus
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Delaware
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Lewes, Delaware, Förenta staterna, 19958
- Beebe Medical Center
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Newark, Delaware, Förenta staterna, 19713
- Helen F Graham Cancer Center
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Newark, Delaware, Förenta staterna, 19713
- Medical Oncology Hematology Consultants PA
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Rehoboth Beach, Delaware, Förenta staterna, 19971
- Beebe Health Campus
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Seaford, Delaware, Förenta staterna, 19973
- TidalHealth Nanticoke / Allen Cancer Center
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District of Columbia
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Washington D.C., District of Columbia, Förenta staterna, 20010
- MedStar Washington Hospital Center
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Washington D.C., District of Columbia, Förenta staterna, 20007
- MedStar Georgetown University Hospital
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Washington D.C., District of Columbia, Förenta staterna, 20016
- Sibley Memorial Hospital
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Florida
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Boca Raton, Florida, Förenta staterna, 33486
- Boca Raton Regional Hospital
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Coral Gables, Florida, Förenta staterna, 33146
- UM Sylvester Comprehensive Cancer Center at Coral Gables
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Daytona Beach, Florida, Förenta staterna, 32114
- Halifax Health Cancer Center for Hope - Daytona Beach
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Deerfield Beach, Florida, Förenta staterna, 33442
- UM Sylvester Comprehensive Cancer Center at Deerfield Beach
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Hollywood, Florida, Förenta staterna, 33021
- Memorial Regional Hospital/Joe DiMaggio Children's Hospital
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Hollywood, Florida, Förenta staterna, 33021
- UM Sylvester Comprehensive Cancer Center at Hollywood
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Jacksonville, Florida, Förenta staterna, 32207
- Baptist MD Anderson Cancer Center
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Lakeland, Florida, Förenta staterna, 33805
- The Watson Clinic
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Miami, Florida, Förenta staterna, 33136
- University of Miami Miller School of Medicine-Sylvester Cancer Center
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Miami, Florida, Förenta staterna, 33176
- UM Sylvester Comprehensive Cancer Center at Kendall
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Miami Beach, Florida, Förenta staterna, 33140
- Mount Sinai Medical Center
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Pembroke Pines, Florida, Förenta staterna, 33028
- Memorial Hospital West
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Pensacola, Florida, Förenta staterna, 32504
- Sacred Heart Hospital
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Plantation, Florida, Förenta staterna, 33324
- UM Sylvester Comprehensive Cancer Center at Plantation
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Tampa, Florida, Förenta staterna, 33612
- Moffitt Cancer Center
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Vero Beach, Florida, Förenta staterna, 32960
- Indian River Medical Center
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Weston, Florida, Förenta staterna, 33331
- Cleveland Clinic-Weston
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Georgia
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Albany, Georgia, Förenta staterna, 31701
- Phoebe Putney Memorial Hospital
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Athens, Georgia, Förenta staterna, 30607
- University Cancer and Blood Center LLC
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Atlanta, Georgia, Förenta staterna, 30308
- Emory University Hospital Midtown
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Atlanta, Georgia, Förenta staterna, 30322
- Emory University Hospital/Winship Cancer Institute
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Atlanta, Georgia, Förenta staterna, 30342
- Emory Saint Joseph's Hospital
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Atlanta, Georgia, Förenta staterna, 30342
- Northside Hospital
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Columbus, Georgia, Förenta staterna, 31904
- John B Amos Cancer Center
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Decatur, Georgia, Förenta staterna, 30033
- Atlanta VA Medical Center
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Decatur, Georgia, Förenta staterna, 30033
- Emory Decatur Hospital
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Gainesville, Georgia, Förenta staterna, 30501
- Northeast Georgia Medical Center-Gainesville
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Lawrenceville, Georgia, Förenta staterna, 30046
- Northside Hospital - Gwinnett
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Savannah, Georgia, Förenta staterna, 31405
- Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
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Savannah, Georgia, Förenta staterna, 31404
- Memorial Health University Medical Center
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Savannah, Georgia, Förenta staterna, 31404
- Summit Cancer Care-Memorial
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Valdosta, Georgia, Förenta staterna, 31602
- South Georgia Medical Center/Pearlman Cancer Center
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Hawaii
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Honolulu, Hawaii, Förenta staterna, 96813
- Queen's Medical Center
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Honolulu, Hawaii, Förenta staterna, 96813
- Hawaii Cancer Care Inc - Waterfront Plaza
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Honolulu, Hawaii, Förenta staterna, 96813
- Queen's Cancer Cenrer - POB I
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Honolulu, Hawaii, Förenta staterna, 96813
- Straub Clinic and Hospital
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Honolulu, Hawaii, Förenta staterna, 96813
- University of Hawaii Cancer Center
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Honolulu, Hawaii, Förenta staterna, 96817
- Hawaii Cancer Care Inc-Liliha
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Honolulu, Hawaii, Förenta staterna, 96817
- Kuakini Medical Center
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Honolulu, Hawaii, Förenta staterna, 96817
- Queen's Cancer Center - Kuakini
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Honolulu, Hawaii, Förenta staterna, 96826
- Kapiolani Medical Center for Women and Children
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‘Aiea, Hawaii, Förenta staterna, 96701
- Pali Momi Medical Center
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‘Aiea, Hawaii, Förenta staterna, 96701
- Queen's Cancer Center - Pearlridge
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Idaho
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Boise, Idaho, Förenta staterna, 83706
- Saint Alphonsus Cancer Care Center-Boise
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Boise, Idaho, Förenta staterna, 83712
- Saint Luke's Cancer Institute - Boise
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Caldwell, Idaho, Förenta staterna, 83605
- Saint Alphonsus Cancer Care Center-Caldwell
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Coeur d'Alene, Idaho, Förenta staterna, 83814
- Kootenai Health - Coeur d'Alene
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Fruitland, Idaho, Förenta staterna, 83619
- Saint Luke's Cancer Institute - Fruitland
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Meridian, Idaho, Förenta staterna, 83642
- Saint Luke's Cancer Institute - Meridian
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Nampa, Idaho, Förenta staterna, 83687
- Saint Alphonsus Cancer Care Center-Nampa
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Nampa, Idaho, Förenta staterna, 83687
- Saint Luke's Cancer Institute - Nampa
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Post Falls, Idaho, Förenta staterna, 83854
- Kootenai Clinic Cancer Services - Post Falls
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Sandpoint, Idaho, Förenta staterna, 83864
- Kootenai Clinic Cancer Services - Sandpoint
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Twin Falls, Idaho, Förenta staterna, 83301
- Saint Luke's Cancer Institute - Twin Falls
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Illinois
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Aurora, Illinois, Förenta staterna, 60504
- Rush-Copley Medical Center
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Bloomington, Illinois, Förenta staterna, 61704
- Illinois CancerCare-Bloomington
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Canton, Illinois, Förenta staterna, 61520
- Illinois CancerCare-Canton
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Carterville, Illinois, Förenta staterna, 62918
- SIH Cancer Institute
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Carthage, Illinois, Förenta staterna, 62321
- Illinois CancerCare-Carthage
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Centralia, Illinois, Förenta staterna, 62801
- Centralia Oncology Clinic
-
Chicago, Illinois, Förenta staterna, 60611
- Northwestern University
-
Chicago, Illinois, Förenta staterna, 60637
- University of Chicago Comprehensive Cancer Center
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Chicago, Illinois, Förenta staterna, 60612
- John H Stroger Jr Hospital of Cook County
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Chicago, Illinois, Förenta staterna, 60608
- Mount Sinai Hospital Medical Center
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Chicago, Illinois, Förenta staterna, 60657
- Advocate Illinois Masonic Medical Center
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Chicago, Illinois, Förenta staterna, 60612
- Rush MD Anderson Cancer Center
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Danville, Illinois, Förenta staterna, 61832
- Carle at The Riverfront
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DeKalb, Illinois, Förenta staterna, 60115
- Northwestern Medicine Cancer Center Kishwaukee
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Decatur, Illinois, Förenta staterna, 62526
- Decatur Memorial Hospital
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Decatur, Illinois, Förenta staterna, 62526
- Cancer Care Specialists of Illinois - Decatur
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Downers Grove, Illinois, Förenta staterna, 60515
- Advocate Good Samaritan Hospital
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Effingham, Illinois, Förenta staterna, 62401
- Crossroads Cancer Center
-
Effingham, Illinois, Förenta staterna, 62401
- Carle Physician Group-Effingham
-
Elmhurst, Illinois, Förenta staterna, 60126
- Elmhurst Memorial Hospital
-
Eureka, Illinois, Förenta staterna, 61530
- Illinois CancerCare-Eureka
-
Evanston, Illinois, Förenta staterna, 60201
- NorthShore University HealthSystem-Evanston Hospital
-
Galesburg, Illinois, Förenta staterna, 61401
- Illinois CancerCare-Galesburg
-
Geneva, Illinois, Förenta staterna, 60134
- Northwestern Medicine Cancer Center Delnor
-
Glenview, Illinois, Förenta staterna, 60026
- NorthShore University HealthSystem-Glenbrook Hospital
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Harvey, Illinois, Förenta staterna, 60426
- Ingalls Memorial Hospital
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Highland Park, Illinois, Förenta staterna, 60035
- NorthShore University HealthSystem-Highland Park Hospital
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Hines, Illinois, Förenta staterna, 60141
- Edward Hines Jr VA Hospital
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Joliet, Illinois, Förenta staterna, 60435
- Duly Health and Care Joliet
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Kewanee, Illinois, Förenta staterna, 61443
- Illinois CancerCare-Kewanee Clinic
-
Macomb, Illinois, Förenta staterna, 61455
- Illinois CancerCare-Macomb
-
Mattoon, Illinois, Förenta staterna, 61938
- Carle Physician Group-Mattoon/Charleston
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Maywood, Illinois, Förenta staterna, 60153
- Loyola University Medical Center
-
Moline, Illinois, Förenta staterna, 61265
- Trinity Medical Center
-
Naperville, Illinois, Förenta staterna, 60540
- Edward Hospital/Cancer Center
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New Lenox, Illinois, Förenta staterna, 60451
- UC Comprehensive Cancer Center at Silver Cross
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O'Fallon, Illinois, Förenta staterna, 62269
- Cancer Care Center of O'Fallon
-
Oak Lawn, Illinois, Förenta staterna, 60453-2699
- Advocate Christ Medical Center
-
Orland Park, Illinois, Förenta staterna, 60462
- University of Chicago Medicine-Orland Park
-
Ottawa, Illinois, Förenta staterna, 61350
- Illinois CancerCare-Ottawa Clinic
-
Pekin, Illinois, Förenta staterna, 61554
- Illinois CancerCare-Pekin
-
Peoria, Illinois, Förenta staterna, 61615
- Illinois CancerCare-Peoria
-
Peru, Illinois, Förenta staterna, 61354
- Illinois CancerCare-Peru
-
Plainfield, Illinois, Förenta staterna, 60585
- Edward Hospital/Cancer Center?Plainfield
-
Princeton, Illinois, Förenta staterna, 61356
- Illinois CancerCare-Princeton
-
Quincy, Illinois, Förenta staterna, 62301
- Quincy Medical Group-Clinic
-
Rockford, Illinois, Förenta staterna, 61108
- OSF Saint Anthony Medical Center
-
Rockford, Illinois, Förenta staterna, 61114
- UW Health Carbone Cancer Center Rockford
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Silvis, Illinois, Förenta staterna, 61282
- MercyOne Genesis Silvis Cancer Center
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Springfield, Illinois, Förenta staterna, 62702
- Southern Illinois University School of Medicine
-
Springfield, Illinois, Förenta staterna, 62702
- Springfield Clinic
-
Springfield, Illinois, Förenta staterna, 62702
- Central Illinois Hematology Oncology Center
-
Springfield, Illinois, Förenta staterna, 62781
- Springfield Memorial Hospital
-
Urbana, Illinois, Förenta staterna, 61801
- Carle Cancer Center
-
Urbana, Illinois, Förenta staterna, 61801
- The Carle Foundation Hospital
-
Warrenville, Illinois, Förenta staterna, 60555
- Northwestern Medicine Cancer Center Warrenville
-
Yorkville, Illinois, Förenta staterna, 60560
- Rush-Copley Healthcare Center
-
-
Indiana
-
Fort Wayne, Indiana, Förenta staterna, 46845
- Parkview Regional Medical Center
-
Goshen, Indiana, Förenta staterna, 46526
- Goshen Center for Cancer Care
-
Indianapolis, Indiana, Förenta staterna, 46237
- Franciscan Health Indianapolis
-
Indianapolis, Indiana, Förenta staterna, 46202
- Indiana University/Melvin and Bren Simon Cancer Center
-
Indianapolis, Indiana, Förenta staterna, 46219
- Community Cancer Center East
-
Indianapolis, Indiana, Förenta staterna, 46227
- Community Cancer Center South
-
Indianapolis, Indiana, Förenta staterna, 46256
- Community Cancer Center North
-
Indianapolis, Indiana, Förenta staterna, 46202
- Sidney and Lois Eskenazi Hospital
-
Indianapolis, Indiana, Förenta staterna, 46202
- Richard L. Roudebush Veterans Affairs Medical Center
-
Kokomo, Indiana, Förenta staterna, 46904
- Community Howard Regional Health
-
Mishawaka, Indiana, Förenta staterna, 46545
- Memorial Regional Cancer Center Day Road
-
Mooresville, Indiana, Förenta staterna, 46158
- Franciscan Health Mooresville
-
Munster, Indiana, Förenta staterna, 46321
- The Community Hospital
-
Richmond, Indiana, Förenta staterna, 47374
- Reid Health
-
South Bend, Indiana, Förenta staterna, 46601
- Memorial Hospital of South Bend
-
Terre Haute, Indiana, Förenta staterna, 47804
- Union Hospital
-
-
Iowa
-
Ames, Iowa, Förenta staterna, 50010
- Mary Greeley Medical Center
-
Ames, Iowa, Förenta staterna, 50010
- McFarland Clinic - Ames
-
Bettendorf, Iowa, Förenta staterna, 52722
- University of Iowa Healthcare Cancer Services Quad Cities
-
Boone, Iowa, Förenta staterna, 50036
- McFarland Clinic - Boone
-
Cedar Rapids, Iowa, Förenta staterna, 52403
- Mercy Hospital
-
Cedar Rapids, Iowa, Förenta staterna, 52403
- Oncology Associates at Mercy Medical Center
-
Cedar Rapids, Iowa, Förenta staterna, 52402
- Physicians' Clinic of Iowa PC
-
Clive, Iowa, Förenta staterna, 50325
- Mercy Cancer Center-West Lakes
-
Clive, Iowa, Förenta staterna, 50325
- UI Health Care Mission Cancer and Blood - West Des Moines Clinic
-
Creston, Iowa, Förenta staterna, 50801
- Greater Regional Medical Center
-
Davenport, Iowa, Förenta staterna, 52807
- Iowa Cancer Specialists
-
Davenport, Iowa, Förenta staterna, 52804
- MercyOne Genesis Davenport Cancer Center
-
Davenport, Iowa, Förenta staterna, 52803
- MercyOne Genesis Davenport Medical Center
-
Des Moines, Iowa, Förenta staterna, 50309
- Iowa Methodist Medical Center
-
Des Moines, Iowa, Förenta staterna, 50314
- Mercy Medical Center - Des Moines
-
Des Moines, Iowa, Förenta staterna, 50316
- Iowa Lutheran Hospital
-
Des Moines, Iowa, Förenta staterna, 50309
- UI Health Care Mission Cancer and Blood - Des Moines Clinic
-
Des Moines, Iowa, Förenta staterna, 50314
- UI Health Care Mission Cancer and Blood - Laurel Clinic
-
Fort Dodge, Iowa, Förenta staterna, 50501
- McFarland Clinic - Trinity Cancer Center
-
Iowa City, Iowa, Förenta staterna, 52242
- University of Iowa/Holden Comprehensive Cancer Center
-
Iowa City, Iowa, Förenta staterna, 52246
- Iowa City VA Healthcare System
-
Jefferson, Iowa, Förenta staterna, 50129
- McFarland Clinic - Jefferson
-
Marshalltown, Iowa, Förenta staterna, 50158
- McFarland Clinic - Marshalltown
-
Sioux City, Iowa, Förenta staterna, 51101
- Siouxland Regional Cancer Center
-
West Des Moines, Iowa, Förenta staterna, 50266
- Mercy Medical Center-West Lakes
-
-
Kansas
-
Chanute, Kansas, Förenta staterna, 66720
- Cancer Center of Kansas - Chanute
-
Dodge City, Kansas, Förenta staterna, 67801
- Cancer Center of Kansas - Dodge City
-
El Dorado, Kansas, Förenta staterna, 67042
- Cancer Center of Kansas - El Dorado
-
Fort Scott, Kansas, Förenta staterna, 66701
- Cancer Center of Kansas - Fort Scott
-
Garden City, Kansas, Förenta staterna, 67846
- Saint Catherine Hospital
-
Great Bend, Kansas, Förenta staterna, 67530
- Central Care Cancer Center - Great Bend
-
Hays, Kansas, Förenta staterna, 67601
- HaysMed
-
Independence, Kansas, Förenta staterna, 67301
- Cancer Center of Kansas-Independence
-
Kansas City, Kansas, Förenta staterna, 66160
- University of Kansas Cancer Center
-
Kansas City, Kansas, Förenta staterna, 66112
- University of Kansas Cancer Center-West
-
Kingman, Kansas, Förenta staterna, 67068
- Cancer Center of Kansas-Kingman
-
Lawrence, Kansas, Förenta staterna, 66044
- Lawrence Memorial Hospital
-
Liberal, Kansas, Förenta staterna, 67905
- Cancer Center of Kansas-Liberal
-
McPherson, Kansas, Förenta staterna, 67460
- Cancer Center of Kansas - McPherson
-
Olathe, Kansas, Förenta staterna, 66061
- The University of Kansas Cancer Center - Olathe
-
Overland Park, Kansas, Förenta staterna, 66210
- University of Kansas Cancer Center-Overland Park
-
Overland Park, Kansas, Förenta staterna, 66213
- Saint Luke's South Hospital
-
Parsons, Kansas, Förenta staterna, 67357
- Cancer Center of Kansas - Parsons
-
Pittsburg, Kansas, Förenta staterna, 66762
- Mercy Hospital Pittsburg
-
Pratt, Kansas, Förenta staterna, 67124
- Cancer Center of Kansas - Pratt
-
Salina, Kansas, Förenta staterna, 67401
- Salina Regional Health Center
-
Salina, Kansas, Förenta staterna, 67401
- Cancer Center of Kansas - Salina
-
Topeka, Kansas, Förenta staterna, 66606
- University of Kansas Health System Saint Francis Campus
-
Topeka, Kansas, Förenta staterna, 66606
- Cotton O'Neil Cancer Center / Stormont Vail Health
-
Wellington, Kansas, Förenta staterna, 67152
- Cancer Center of Kansas - Wellington
-
Westwood, Kansas, Förenta staterna, 66205
- University of Kansas Hospital-Westwood Cancer Center
-
Wichita, Kansas, Förenta staterna, 67214
- Ascension Via Christi Hospitals Wichita
-
Wichita, Kansas, Förenta staterna, 67208
- Cancer Center of Kansas-Wichita Medical Arts Tower
-
Wichita, Kansas, Förenta staterna, 67214
- Cancer Center of Kansas - Wichita
-
Winfield, Kansas, Förenta staterna, 67156
- Cancer Center of Kansas - Winfield
-
-
Kentucky
-
Ashland, Kentucky, Förenta staterna, 41101
- King's Daughter's Medical Center
-
Bardstown, Kentucky, Förenta staterna, 40004
- CommonSpirit Saint Joseph Hospital - Bardstown
-
Corbin, Kentucky, Förenta staterna, 40701
- Baptist Health Corbin
-
Edgewood, Kentucky, Förenta staterna, 41017
- Saint Elizabeth Healthcare Edgewood
-
Elizabethtown, Kentucky, Förenta staterna, 42701
- Baptist Health Hardin
-
Fort Thomas, Kentucky, Förenta staterna, 41075
- Saint Elizabeth Healthcare Fort Thomas
-
Lexington, Kentucky, Förenta staterna, 40536
- University of Kentucky/Markey Cancer Center
-
Lexington, Kentucky, Förenta staterna, 40503
- Baptist Health Lexington
-
Lexington, Kentucky, Förenta staterna, 40509
- CommonSpirit Saint Joseph Medical Center - East Lexington
-
London, Kentucky, Förenta staterna, 40741
- CommonSpirit Saint Joseph Hospital London
-
Louisville, Kentucky, Förenta staterna, 40202
- The James Graham Brown Cancer Center at University of Louisville
-
Louisville, Kentucky, Förenta staterna, 40202
- Jewish Hospital
-
Louisville, Kentucky, Förenta staterna, 40245
- UofL Health Medical Center Northeast
-
Louisville, Kentucky, Förenta staterna, 40207
- Baptist Health Louisville
-
Louisville, Kentucky, Förenta staterna, 40215
- Saints Mary and Elizabeth Hospital
-
Madisonville, Kentucky, Förenta staterna, 42431
- Baptist Health Madisonville/Merle Mahr Cancer Center
-
Paducah, Kentucky, Förenta staterna, 42003
- Baptist Health Paducah
-
-
Louisiana
-
Alexandria, Louisiana, Förenta staterna, 71301
- Christus Saint Frances Cabrini Hospital
-
Baton Rouge, Louisiana, Förenta staterna, 70805
- LSU Health Baton Rouge-North Clinic
-
Baton Rouge, Louisiana, Förenta staterna, 70809
- Louisiana Hematology Oncology Associates LLC
-
Baton Rouge, Louisiana, Förenta staterna, 70809
- Mary Bird Perkins Cancer Center
-
Baton Rouge, Louisiana, Förenta staterna, 70809
- Ochsner Health Center-Summa
-
Baton Rouge, Louisiana, Förenta staterna, 70816
- Medical Center of Baton Rouge
-
Baton Rouge, Louisiana, Förenta staterna, 70808
- Our Lady of the Lake Physician Group
-
Covington, Louisiana, Förenta staterna, 70433
- Northshore Oncology Associates-Covington
-
Covington, Louisiana, Förenta staterna, 70433
- Ochsner Hematology Oncology North Shore - Covington (West Region)
-
Houma, Louisiana, Förenta staterna, 70360
- Oncology Center of The South Incorporated
-
Kenner, Louisiana, Förenta staterna, 70065
- Ochsner Medical Center Kenner
-
Lake Charles, Louisiana, Förenta staterna, 70601
- CHRISTUS Saint Patrick Hospital
-
Monroe, Louisiana, Förenta staterna, 71202
- Ochsner LSU Health Monroe Medical Center
-
New Orleans, Louisiana, Förenta staterna, 70121
- Ochsner Medical Center Jefferson
-
New Orleans, Louisiana, Förenta staterna, 70112
- University Medical Center New Orleans
-
Shreveport, Louisiana, Förenta staterna, 71103
- LSU Health Sciences Center at Shreveport
-
Shreveport, Louisiana, Förenta staterna, 71105
- CHRISTUS Highland Medical Center
-
Slidell, Louisiana, Förenta staterna, 70458
- Ochsner Hematology Oncology North Shore - Slidell (East Region)
-
-
Maine
-
Augusta, Maine, Förenta staterna, 04330
- Harold Alfond Center for Cancer Care
-
Bangor, Maine, Förenta staterna, 04401
- Eastern Maine Medical Center
-
Belfast, Maine, Förenta staterna, 04915
- MaineHealth Waldo Hospital
-
Biddeford, Maine, Förenta staterna, 04005
- MaineHealth Maine Medical Center - Biddeford
-
Brewer, Maine, Förenta staterna, 04412
- Lafayette Family Cancer Center-EMMC
-
Kennebunk, Maine, Förenta staterna, 04043
- New England Cancer Specialists - Kennebunk
-
Rockport, Maine, Förenta staterna, 04856
- Penobscot Bay Medical Center
-
Sanford, Maine, Förenta staterna, 04073
- MaineHealth Cancer Care and IV Therapy - Sanford
-
South Portland, Maine, Förenta staterna, 04106
- MaineHealth Cancer Care and IV Therapy - South Portland
-
Topsham, Maine, Förenta staterna, 04086
- New England Cancer Specialists - Topsham
-
Westbrook, Maine, Förenta staterna, 04092
- New England Cancer Specialists
-
-
Maryland
-
Annapolis, Maryland, Förenta staterna, 21401
- Luminis Health Anne Arundel Medical Center
-
Baltimore, Maryland, Förenta staterna, 21237
- MedStar Franklin Square Medical Center/Weinberg Cancer Institute
-
Baltimore, Maryland, Förenta staterna, 21287
- Johns Hopkins University/Sidney Kimmel Cancer Center
-
Baltimore, Maryland, Förenta staterna, 21215
- Sinai Hospital of Baltimore
-
Baltimore, Maryland, Förenta staterna, 21204
- Greater Baltimore Medical Center
-
Baltimore, Maryland, Förenta staterna, 21201
- University of Maryland/Greenebaum Cancer Center
-
Bel Air, Maryland, Förenta staterna, 21014
- UM Upper Chesapeake Medical Center
-
Cumberland, Maryland, Förenta staterna, 21502
- UPMC Western Maryland
-
Elkton, Maryland, Förenta staterna, 21921
- Christiana Care - Union Hospital
-
Glen Burnie, Maryland, Förenta staterna, 21061
- UM Baltimore Washington Medical Center/Tate Cancer Center
-
Randallstown, Maryland, Förenta staterna, 21133
- Northwest Hospital Center
-
Salisbury, Maryland, Förenta staterna, 21801
- TidalHealth Peninsula Regional
-
-
Massachusetts
-
Beverly, Massachusetts, Förenta staterna, 01915
- Beverly Hospital
-
Boston, Massachusetts, Förenta staterna, 02215
- Beth Israel Deaconess Medical Center
-
Boston, Massachusetts, Förenta staterna, 02215
- Dana-Farber Cancer Institute
-
Boston, Massachusetts, Förenta staterna, 02118
- Boston Medical Center
-
Boston, Massachusetts, Förenta staterna, 02114
- Massachusetts General Hospital Cancer Center
-
Brighton, Massachusetts, Förenta staterna, 02135
- Dana-Farber Cancer Institute at Boston Medical Center - Brighton
-
Burlington, Massachusetts, Förenta staterna, 01805
- Lahey Clinic
-
Fitchburg, Massachusetts, Förenta staterna, 01420
- Simonds-Sinon Regional Cancer Center
-
Gloucester, Massachusetts, Förenta staterna, 01930
- Addison Gilbert Hospital
-
Milford, Massachusetts, Förenta staterna, 01757
- Dana-Farber/Brigham and Women's Cancer Center at Milford Regional
-
Newton, Massachusetts, Förenta staterna, 02462
- Newton-Wellesley Hospital
-
Pittsfield, Massachusetts, Förenta staterna, 01201
- Berkshire Medical Center - Cancer Center
-
South Weymouth, Massachusetts, Förenta staterna, 02190
- Dana-Farber/Brigham and Women's Cancer Center at South Shore
-
Springfield, Massachusetts, Förenta staterna, 01199
- Baystate Medical Center
-
Winchester, Massachusetts, Förenta staterna, 01890
- Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care
-
Worcester, Massachusetts, Förenta staterna, 01655
- UMass Memorial Medical Center - University Campus
-
-
Michigan
-
Ann Arbor, Michigan, Förenta staterna, 48109
- University of Michigan Rogel Cancer Center
-
Ann Arbor, Michigan, Förenta staterna, 48106
- Trinity Health Saint Joseph Mercy Hospital Ann Arbor
-
Battle Creek, Michigan, Förenta staterna, 49017
- Bronson Battle Creek
-
Brighton, Michigan, Förenta staterna, 48114
- Trinity Health IHA Medical Group Hematology Oncology - Brighton
-
Brighton, Michigan, Förenta staterna, 48114
- Trinity Health Medical Center - Brighton
-
Brownstown, Michigan, Förenta staterna, 48183
- Henry Ford Cancer Institute-Downriver
-
Canton, Michigan, Förenta staterna, 48188
- Trinity Health IHA Medical Group Hematology Oncology - Canton
-
Canton, Michigan, Förenta staterna, 48188
- Trinity Health Medical Center - Canton
-
Chelsea, Michigan, Förenta staterna, 48118
- Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
-
Chelsea, Michigan, Förenta staterna, 48118
- Chelsea Hospital
-
Clarkston, Michigan, Förenta staterna, 48346
- Newland Medical Associates-Clarkston
-
Dearborn, Michigan, Förenta staterna, 48126
- Henry Ford Medical Center-Fairlane
-
Detroit, Michigan, Förenta staterna, 48202
- Henry Ford Hospital
-
Detroit, Michigan, Förenta staterna, 48236
- Henry Ford Health Saint John Hospital
-
Escanaba, Michigan, Förenta staterna, 49829
- OSF Saint Francis Hospital and Medical Group
-
Farmington Hills, Michigan, Förenta staterna, 48336
- Corewell Health Farmington Hills Hospital
-
Flint, Michigan, Förenta staterna, 48503
- Genesys Hurley Cancer Institute
-
Grand Rapids, Michigan, Förenta staterna, 49503
- Trinity Health Grand Rapids Hospital
-
Grand Rapids, Michigan, Förenta staterna, 49503
- Corewell Health Grand Rapids Hospitals - Butterworth Hospital
-
Jackson, Michigan, Förenta staterna, 49201
- Allegiance Health
-
Kalamazoo, Michigan, Förenta staterna, 49007
- West Michigan Cancer Center
-
Lansing, Michigan, Förenta staterna, 48912
- University of Michigan Health - Sparrow Lansing
-
Livonia, Michigan, Förenta staterna, 48154
- Trinity Health Saint Mary Mercy Livonia Hospital
-
Marquette, Michigan, Förenta staterna, 49855
- UP Health System Marquette
-
Marquette, Michigan, Förenta staterna, 49855
- UP Health System Hematology Oncology Marquette
-
Midland, Michigan, Förenta staterna, 48670
- MyMichigan Medical Center Midland
-
Muskegon, Michigan, Förenta staterna, 49444
- Trinity Health Muskegon Hospital
-
Novi, Michigan, Förenta staterna, 48377
- Henry Ford Medical Center-Columbus
-
Novi, Michigan, Förenta staterna, 48374
- Henry Ford Health Providence Novi Hospital
-
Pontiac, Michigan, Förenta staterna, 48341
- Trinity Health Saint Joseph Mercy Oakland Hospital
-
Reed City, Michigan, Förenta staterna, 49677
- Corewell Health Reed City Hospital
-
Royal Oak, Michigan, Förenta staterna, 48073
- Corewell Health William Beaumont University Hospital
-
Saginaw, Michigan, Förenta staterna, 48601
- MyMichigan Medical Center Saginaw
-
Saint Joseph, Michigan, Förenta staterna, 49085
- Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
-
Southfield, Michigan, Förenta staterna, 48075
- Henry Ford Health Providence Southfield Hospital
-
Troy, Michigan, Förenta staterna, 48085
- Corewell Health Beaumont Troy Hospital
-
Warren, Michigan, Förenta staterna, 48093
- Henry Ford Health Warren Hospital
-
West Bloomfield, Michigan, Förenta staterna, 48322
- Henry Ford West Bloomfield Hospital
-
Wyoming, Michigan, Förenta staterna, 49519
- University of Michigan Health - West
-
Ypsilanti, Michigan, Förenta staterna, 48197
- Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
-
-
Minnesota
-
Bemidji, Minnesota, Förenta staterna, 56601
- Sanford Joe Lueken Cancer Center
-
Brainerd, Minnesota, Förenta staterna, 56401
- Essentia Health Saint Joseph's Medical Center
-
Burnsville, Minnesota, Förenta staterna, 55337
- Fairview Ridges Hospital
-
Coon Rapids, Minnesota, Förenta staterna, 55433
- Mercy Hospital
-
Duluth, Minnesota, Förenta staterna, 55805
- Saint Luke's Hospital of Duluth
-
Duluth, Minnesota, Förenta staterna, 55805
- Essentia Health Cancer Center
-
Edina, Minnesota, Förenta staterna, 55435
- Fairview Southdale Hospital
-
Fridley, Minnesota, Förenta staterna, 55432
- Unity Hospital
-
Hibbing, Minnesota, Förenta staterna, 55746
- Essentia Health Hibbing Clinic
-
Maplewood, Minnesota, Förenta staterna, 55109
- Saint John's Hospital - Healtheast
-
Maplewood, Minnesota, Förenta staterna, 55109
- Minnesota Oncology Hematology PA-Maplewood
-
Minneapolis, Minnesota, Förenta staterna, 55415
- Hennepin County Medical Center
-
Minneapolis, Minnesota, Förenta staterna, 55407
- Abbott-Northwestern Hospital
-
Minneapolis, Minnesota, Förenta staterna, 55454
- Health Partners Inc
-
Minneapolis, Minnesota, Förenta staterna, 55417
- Minneapolis VA Medical Center
-
New Ulm, Minnesota, Förenta staterna, 56073
- New Ulm Medical Center
-
Robbinsdale, Minnesota, Förenta staterna, 55422
- North Memorial Medical Health Center
-
Rochester, Minnesota, Förenta staterna, 55905
- Mayo Clinic in Rochester
-
Saint Cloud, Minnesota, Förenta staterna, 56303
- Coborn Cancer Center at Saint Cloud Hospital
-
Saint Louis Park, Minnesota, Förenta staterna, 55416
- Park Nicollet Clinic - Saint Louis Park
-
Saint Paul, Minnesota, Förenta staterna, 55101
- Regions Hospital
-
Saint Paul, Minnesota, Förenta staterna, 55102
- United Hospital
-
Shakopee, Minnesota, Förenta staterna, 55379
- Saint Francis Regional Medical Center
-
Stillwater, Minnesota, Förenta staterna, 55082
- Lakeview Hospital
-
Virginia, Minnesota, Förenta staterna, 55792
- Essentia Health Virginia Clinic
-
Waconia, Minnesota, Förenta staterna, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, Förenta staterna, 56201
- Rice Memorial Hospital
-
Woodbury, Minnesota, Förenta staterna, 55125
- Minnesota Oncology Hematology PA-Woodbury
-
-
Mississippi
-
Columbus, Mississippi, Förenta staterna, 39705
- Baptist Memorial Hospital and Cancer Center-Golden Triangle
-
Grenada, Mississippi, Förenta staterna, 38901
- Baptist Cancer Center-Grenada
-
Hattiesburg, Mississippi, Förenta staterna, 39401
- Hattiesburg Clinic - Hematology/Oncology Clinic
-
Hattiesburg, Mississippi, Förenta staterna, 39404
- Forrest General Hospital / Cancer Center
-
Jackson, Mississippi, Förenta staterna, 39216
- University of Mississippi Medical Center
-
New Albany, Mississippi, Förenta staterna, 38652
- Baptist Memorial Hospital and Cancer Center-Union County
-
Oxford, Mississippi, Förenta staterna, 38655
- Baptist Memorial Hospital and Cancer Center-Oxford
-
Pascagoula, Mississippi, Förenta staterna, 39581
- Singing River Hospital
-
Southhaven, Mississippi, Förenta staterna, 38671
- Baptist Memorial Hospital and Cancer Center-Desoto
-
-
Missouri
-
Ballwin, Missouri, Förenta staterna, 63011
- Mercy Oncology and Hematology - Clayton-Clarkson
-
Bonne Terre, Missouri, Förenta staterna, 63628
- Parkland Health Center-Bonne Terre
-
Cape Girardeau, Missouri, Förenta staterna, 63703
- Saint Francis Medical Center
-
Cape Girardeau, Missouri, Förenta staterna, 63703
- Mercy Cancer Center - Cape Girardeau
-
Chesterfield, Missouri, Förenta staterna, 63017
- Saint Luke's Hospital
-
City of Saint Peters, Missouri, Förenta staterna, 63376
- Siteman Cancer Center at Saint Peters Hospital
-
Columbia, Missouri, Förenta staterna, 65212
- MU Health - University Hospital/Ellis Fischel Cancer Center
-
Creve Coeur, Missouri, Förenta staterna, 63141
- Siteman Cancer Center at West County Hospital
-
Jefferson City, Missouri, Förenta staterna, 65109
- MU Health Care Goldschmidt Cancer Center
-
Joplin, Missouri, Förenta staterna, 64804
- Mercy Hospital Joplin
-
Kansas City, Missouri, Förenta staterna, 64154
- University of Kansas Cancer Center - North
-
Kansas City, Missouri, Förenta staterna, 64131
- The University of Kansas Cancer Center-South
-
Kansas City, Missouri, Förenta staterna, 64111
- Saint Luke's Hospital of Kansas City
-
Kansas City, Missouri, Förenta staterna, 64132
- Research Medical Center
-
Kansas City, Missouri, Förenta staterna, 64108
- University Health Truman Medical Center
-
Lee's Summit, Missouri, Förenta staterna, 64064
- University of Kansas Cancer Center - Lee's Summit
-
Lee's Summit, Missouri, Förenta staterna, 64086
- Saint Luke's East - Lee's Summit
-
Sainte Genevieve, Missouri, Förenta staterna, 63670
- Sainte Genevieve County Memorial Hospital
-
Springfield, Missouri, Förenta staterna, 65807
- CoxHealth South Hospital
-
St Louis, Missouri, Förenta staterna, 63110
- Washington University School of Medicine
-
St Louis, Missouri, Förenta staterna, 63129
- Siteman Cancer Center-South County
-
St Louis, Missouri, Förenta staterna, 63136
- Siteman Cancer Center at Christian Hospital
-
St Louis, Missouri, Förenta staterna, 63131
- Missouri Baptist Medical Center
-
St Louis, Missouri, Förenta staterna, 63109
- Mercy Infusion Center - Chippewa
-
St Louis, Missouri, Förenta staterna, 63141
- Mercy Hospital Saint Louis
-
St Louis, Missouri, Förenta staterna, 63125
- Veteran's Affairs Medical Center - Saint Louis
-
Sullivan, Missouri, Förenta staterna, 63080
- Missouri Baptist Sullivan Hospital
-
-
Montana
-
Anaconda, Montana, Förenta staterna, 59711
- Community Hospital of Anaconda
-
Billings, Montana, Förenta staterna, 59101
- Billings Clinic Cancer Center
-
Billings, Montana, Förenta staterna, 59101
- Saint Vincent Healthcare
-
Bozeman, Montana, Förenta staterna, 59715
- Bozeman Health Deaconess Hospital
-
Butte, Montana, Förenta staterna, 59701
- Saint James Community Hospital and Cancer Treatment Center
-
Great Falls, Montana, Förenta staterna, 59405
- Great Falls Clinic
-
Great Falls, Montana, Förenta staterna, 59405
- Benefis Sletten Cancer Institute
-
Helena, Montana, Förenta staterna, 59601
- Saint Peter's Community Hospital
-
Kalispell, Montana, Förenta staterna, 59901
- Logan Health Medical Center
-
Missoula, Montana, Förenta staterna, 59802
- Saint Patrick Hospital - Community Hospital
-
Missoula, Montana, Förenta staterna, 59804
- Community Medical Center
-
-
Nebraska
-
Grand Island, Nebraska, Förenta staterna, 68803
- Nebraska Cancer Specialists/Oncology Hematology West PC
-
Kearney, Nebraska, Förenta staterna, 68847
- CHI Health Good Samaritan
-
Lincoln, Nebraska, Förenta staterna, 68516
- Cancer Partners of Nebraska
-
Omaha, Nebraska, Förenta staterna, 68114
- Nebraska Methodist Hospital
-
Omaha, Nebraska, Förenta staterna, 68198
- University of Nebraska Medical Center
-
Omaha, Nebraska, Förenta staterna, 68124
- Alegent Health Bergan Mercy Medical Center
-
Omaha, Nebraska, Förenta staterna, 68122
- Alegent Health Immanuel Medical Center
-
-
Nevada
-
Henderson, Nevada, Förenta staterna, 89052
- Comprehensive Cancer Centers of Nevada - Henderson
-
Henderson, Nevada, Förenta staterna, 89052
- Cancer and Blood Specialists-Henderson
-
Henderson, Nevada, Förenta staterna, 89052
- Las Vegas Cancer Center-Henderson
-
Henderson, Nevada, Förenta staterna, 89074
- Comprehensive Cancer Centers of Nevada-Southeast Henderson
-
Henderson, Nevada, Förenta staterna, 89074
- Oncology Las Vegas - Henderson
-
Las Vegas, Nevada, Förenta staterna, 89144
- Summerlin Hospital Medical Center
-
Las Vegas, Nevada, Förenta staterna, 89102
- OptumCare Cancer Care at Charleston
-
Las Vegas, Nevada, Förenta staterna, 89106
- Radiation Oncology Centers of Nevada Central
-
Las Vegas, Nevada, Förenta staterna, 89119
- Radiation Oncology Centers of Nevada Southeast
-
Las Vegas, Nevada, Förenta staterna, 89128
- Comprehensive Cancer Centers of Nevada - Northwest
-
Las Vegas, Nevada, Förenta staterna, 89128
- OptumCare Cancer Care at MountainView
-
Las Vegas, Nevada, Förenta staterna, 89144
- Comprehensive Cancer Centers of Nevada-Summerlin
-
Las Vegas, Nevada, Förenta staterna, 89148
- Comprehensive Cancer Centers of Nevada
-
Las Vegas, Nevada, Förenta staterna, 89169
- Comprehensive Cancer Centers of Nevada - Central Valley
-
Las Vegas, Nevada, Förenta staterna, 89106
- Cancer and Blood Specialists-Shadow
-
Las Vegas, Nevada, Förenta staterna, 89109
- HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
-
Las Vegas, Nevada, Förenta staterna, 89113
- HealthCare Partners Medical Group Oncology/Hematology-San Martin
-
Las Vegas, Nevada, Förenta staterna, 89121
- Cancer Therapy and Integrative Medicine
-
Las Vegas, Nevada, Förenta staterna, 89128
- Cancer and Blood Specialists-Tenaya
-
Las Vegas, Nevada, Förenta staterna, 89128
- HealthCare Partners Medical Group Oncology/Hematology-Tenaya
-
Las Vegas, Nevada, Förenta staterna, 89148-2405
- Las Vegas Cancer Center-Medical Center
-
Las Vegas, Nevada, Förenta staterna, 89149
- HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
-
Las Vegas, Nevada, Förenta staterna, 89128
- Oncology Las Vegas - Tenaya
-
Las Vegas, Nevada, Förenta staterna, 89183
- OptumCare Cancer Care at Fort Apache
-
Reno, Nevada, Förenta staterna, 89502
- Renown Regional Medical Center
-
Reno, Nevada, Förenta staterna, 89503
- Saint Mary's Regional Medical Center
-
-
New Hampshire
-
Concord, New Hampshire, Förenta staterna, 03301
- New Hampshire Oncology Hematology PA-Concord
-
Dover, New Hampshire, Förenta staterna, 03820
- Wentworth-Douglass Hospital
-
Exeter, New Hampshire, Förenta staterna, 03833
- Exeter Hospital
-
Lebanon, New Hampshire, Förenta staterna, 03756
- Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
-
Londonderry, New Hampshire, Förenta staterna, 03053
- The Dana-Farber Cancer Institute at Londonderry
-
Manchester, New Hampshire, Förenta staterna, 03103
- Solinsky Center for Cancer Care
-
Manchester, New Hampshire, Förenta staterna, 03104
- Dartmouth Cancer Center - Manchester/ DCC Manchester
-
Nashua, New Hampshire, Förenta staterna, 03060
- Saint Joseph Hospital
-
Nashua, New Hampshire, Förenta staterna, 03063
- Dartmouth Cancer Center - Nashua
-
Portsmouth, New Hampshire, Förenta staterna, 03802
- Portsmouth Regional Hospital
-
-
New Jersey
-
Basking Ridge, New Jersey, Förenta staterna, 07920
- Memorial Sloan Kettering Basking Ridge
-
Camden, New Jersey, Förenta staterna, 08103
- Cooper Hospital University Medical Center
-
Hamilton, New Jersey, Förenta staterna, 08690
- The Cancer Institute of New Jersey Hamilton
-
Long Branch, New Jersey, Förenta staterna, 07740
- Monmouth Medical Center
-
Middletown, New Jersey, Förenta staterna, 07748
- Memorial Sloan Kettering Monmouth
-
Montvale, New Jersey, Förenta staterna, 07645
- Memorial Sloan Kettering Bergen
-
Morristown, New Jersey, Förenta staterna, 07960
- Morristown Medical Center
-
Mount Holly, New Jersey, Förenta staterna, 08060
- Virtua Memorial
-
Mullica Hill, New Jersey, Förenta staterna, 08062
- Inspira Medical Center Mullica Hill
-
New Brunswick, New Jersey, Förenta staterna, 08903
- Rutgers Cancer Institute of New Jersey
-
Newton, New Jersey, Förenta staterna, 07860
- Newton Medical Center
-
Paramus, New Jersey, Förenta staterna, 07652
- The Valley Hospital - Luckow Pavilion
-
Pompton, New Jersey, Förenta staterna, 07444
- Chilton Medical Center
-
Ridgewood, New Jersey, Förenta staterna, 07450
- Valley Health System Ridgewood Campus
-
Somerville, New Jersey, Förenta staterna, 08876
- Robert Wood Johnson University Hospital Somerset
-
Summit, New Jersey, Förenta staterna, 07902
- Overlook Hospital
-
Toms River, New Jersey, Förenta staterna, 08755
- Community Medical Center
-
Vineland, New Jersey, Förenta staterna, 08360
- Inspira Medical Center Vineland
-
Voorhees Township, New Jersey, Förenta staterna, 08043
- Virtua Voorhees
-
Westwood, New Jersey, Förenta staterna, 07675
- Valley Health System-Hematology/Oncology
-
-
New Mexico
-
Albuquerque, New Mexico, Förenta staterna, 87102
- Lovelace Medical Center-Saint Joseph Square
-
Albuquerque, New Mexico, Förenta staterna, 87102
- Lovelace Medical Center-Downtown
-
Albuquerque, New Mexico, Förenta staterna, 87106
- University of New Mexico Cancer Center
-
Albuquerque, New Mexico, Förenta staterna, 87110
- Presbyterian Kaseman Hospital
-
Las Cruces, New Mexico, Förenta staterna, 88011
- Memorial Medical Center-Las Cruces
-
Rio Rancho, New Mexico, Förenta staterna, 87124
- Presbyterian Rust Medical Center/Jorgensen Cancer Center
-
Santa Fe, New Mexico, Förenta staterna, 87505
- Christus Saint Vincent Regional Cancer Center
-
-
New York
-
Bay Shore, New York, Förenta staterna, 11706
- Northwell Health Imbert Cancer Center
-
Brooklyn, New York, Förenta staterna, 11219
- Maimonides Medical Center
-
Brooklyn, New York, Förenta staterna, 11215
- New York-Presbyterian/Brooklyn Methodist Hospital
-
Buffalo, New York, Förenta staterna, 14263
- Roswell Park Cancer Institute
-
Commack, New York, Förenta staterna, 11725
- Memorial Sloan Kettering Commack
-
Cooperstown, New York, Förenta staterna, 13326
- Mary Imogene Bassett Hospital
-
Glens Falls, New York, Förenta staterna, 12801
- Glens Falls Hospital
-
Harrison, New York, Förenta staterna, 10604
- Memorial Sloan Kettering Westchester
-
Lake Success, New York, Förenta staterna, 11042
- Northwell Health/Center for Advanced Medicine
-
New York, New York, Förenta staterna, 10065
- Memorial Sloan Kettering Cancer Center
-
New York, New York, Förenta staterna, 10032
- NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
-
New York, New York, Förenta staterna, 10065
- NYP/Weill Cornell Medical Center
-
New York, New York, Förenta staterna, 10016
- Laura and Isaac Perlmutter Cancer Center at NYU Langone
-
Poughkeepsie, New York, Förenta staterna, 12601
- Vassar Brothers Medical Center
-
Rochester, New York, Förenta staterna, 14642
- University of Rochester
-
Rochester, New York, Förenta staterna, 14621
- Rochester General Hospital
-
Staten Island, New York, Förenta staterna, 10305
- Staten Island University Hospital
-
Syracuse, New York, Förenta staterna, 13210
- State University of New York Upstate Medical University
-
The Bronx, New York, Förenta staterna, 10461
- Montefiore Medical Center-Einstein Campus
-
The Bronx, New York, Förenta staterna, 10467
- Montefiore Medical Center - Moses Campus
-
The Bronx, New York, Förenta staterna, 10468
- James J Peters VA Medical Center
-
Uniondale, New York, Förenta staterna, 11553
- Memorial Sloan Kettering Nassau
-
White Plains, New York, Förenta staterna, 10601
- Dickstein Cancer Treatment Center
-
-
North Carolina
-
Asheboro, North Carolina, Förenta staterna, 27203
- Randolph Hospital
-
Asheville, North Carolina, Förenta staterna, 28801
- Mission Hospital
-
Asheville, North Carolina, Förenta staterna, 28803
- AdventHealth Infusion Center Asheville
-
Burlington, North Carolina, Förenta staterna, 27215
- Cone Health Cancer Center at Alamance Regional
-
Chapel Hill, North Carolina, Förenta staterna, 27599
- UNC Lineberger Comprehensive Cancer Center
-
Charlotte, North Carolina, Förenta staterna, 28204
- Novant Health Presbyterian Medical Center
-
Charlotte, North Carolina, Förenta staterna, 28207
- Oncology Specialists of Charlotte
-
Charlotte, North Carolina, Förenta staterna, 28262
- Southern Oncology Specialists-Charlotte
-
Clinton, North Carolina, Förenta staterna, 28328
- Southeastern Medical Oncology Center-Clinton
-
Clyde, North Carolina, Förenta staterna, 28721
- AdventHealth Infusion Center Haywood
-
Durham, North Carolina, Förenta staterna, 27710
- Duke University Medical Center
-
Gastonia, North Carolina, Förenta staterna, 28054
- CaroMont Regional Medical Center
-
Gastonia, North Carolina, Förenta staterna, 28054
- Gaston Hematology and Oncology Associates
-
Goldsboro, North Carolina, Förenta staterna, 27534
- Southeastern Medical Oncology Center-Goldsboro
-
Goldsboro, North Carolina, Förenta staterna, 27534
- Wayne Memorial Hospital
-
Greensboro, North Carolina, Förenta staterna, 27403
- Cone Health Cancer Center
-
Greenville, North Carolina, Förenta staterna, 27834
- East Carolina University
-
Henderson, North Carolina, Förenta staterna, 27536
- Maria Parham Hospital
-
Hendersonville, North Carolina, Förenta staterna, 28791
- Margaret R Pardee Memorial Hospital
-
Hendersonville, North Carolina, Förenta staterna, 28792
- AdventHealth Hendersonville
-
Huntersville, North Carolina, Förenta staterna, 28078
- Novant Health Cancer Institute - Huntersville
-
Huntersville, North Carolina, Förenta staterna, 28078
- Southern Oncology Specialists-Huntersville
-
Jacksonville, North Carolina, Förenta staterna, 28546
- Southeastern Medical Oncology Center-Jacksonville
-
Kenansville, North Carolina, Förenta staterna, 28349
- ECU Health Oncology Kenansville
-
Kinston, North Carolina, Förenta staterna, 28501
- ECU Health Oncology Kinston
-
Laurinburg, North Carolina, Förenta staterna, 28352
- Scotland Memorial Hospital-Laurinburg Cancer Center
-
Lumberton, North Carolina, Förenta staterna, 28358
- Southeastern Regional Medical Center
-
Matthews, North Carolina, Förenta staterna, 28105
- Matthews Radiation Oncology Center
-
Matthews, North Carolina, Förenta staterna, 28105
- Novant Health Cancer Institute - Matthews
-
Mooresville, North Carolina, Förenta staterna, 28117
- Novant Health Cancer Institute - Mooresville
-
Pinehurst, North Carolina, Förenta staterna, 28374
- FirstHealth of the Carolinas-Moore Regional Hospital
-
Raleigh, North Carolina, Förenta staterna, 27609
- Duke Cancer Center Raleigh
-
Richlands, North Carolina, Förenta staterna, 28574
- ECU Health Oncology Richlands
-
Smithfield, North Carolina, Förenta staterna, 27577
- Johnston Memorial Hospital
-
Washington, North Carolina, Förenta staterna, 27889
- Marion L Shepard Cancer Center - ECU Health Beaufort Hospital
-
Winston-Salem, North Carolina, Förenta staterna, 27157
- Wake Forest University Health Sciences
-
-
North Dakota
-
Bismarck, North Dakota, Förenta staterna, 58501
- Sanford Bismarck Medical Center
-
Fargo, North Dakota, Förenta staterna, 58122
- Sanford Roger Maris Cancer Center
-
Fargo, North Dakota, Förenta staterna, 58122
- Sanford Broadway Medical Center
-
Grand Forks, North Dakota, Förenta staterna, 58201
- Altru Cancer Center
-
-
Ohio
-
Akron, Ohio, Förenta staterna, 44307
- Cleveland Clinic Akron General
-
Canton, Ohio, Förenta staterna, 44710
- Aultman Health Foundation
-
Centerville, Ohio, Förenta staterna, 45459
- Dayton Physicians LLC-Miami Valley South
-
Chardon, Ohio, Förenta staterna, 44024
- Geauga Hospital
-
Chillicothe, Ohio, Förenta staterna, 45601
- Adena Regional Medical Center
-
Cincinnati, Ohio, Förenta staterna, 45219
- University of Cincinnati Cancer Center-UC Medical Center
-
Cincinnati, Ohio, Förenta staterna, 45220
- Good Samaritan Hospital - Cincinnati
-
Cincinnati, Ohio, Förenta staterna, 45242
- Bethesda North Hospital
-
Cincinnati, Ohio, Förenta staterna, 45247
- TriHealth Cancer Institute-Westside
-
Cincinnati, Ohio, Förenta staterna, 45255
- TriHealth Cancer Institute-Anderson
-
Cleveland, Ohio, Förenta staterna, 44106
- Case Western Reserve University
-
Cleveland, Ohio, Förenta staterna, 44109
- MetroHealth Medical Center
-
Cleveland, Ohio, Förenta staterna, 44195
- Cleveland Clinic Foundation
-
Cleveland, Ohio, Förenta staterna, 44111
- Cleveland Clinic Cancer Center/Fairview Hospital
-
Columbus, Ohio, Förenta staterna, 43210
- Ohio State University Comprehensive Cancer Center
-
Columbus, Ohio, Förenta staterna, 43219
- The Mark H Zangmeister Center
-
Columbus, Ohio, Förenta staterna, 43214
- Columbus Oncology and Hematology Associates Inc
-
Columbus, Ohio, Förenta staterna, 43228
- Doctors Hospital
-
Columbus, Ohio, Förenta staterna, 43215
- Grant Medical Center
-
Dayton, Ohio, Förenta staterna, 45428
- Dayton Veterans Affairs Medical Center
-
Elyria, Ohio, Förenta staterna, 44035
- Mercy Cancer Center-Elyria
-
Findlay, Ohio, Förenta staterna, 45840
- Blanchard Valley Hospital
-
Findlay, Ohio, Förenta staterna, 45840
- Armes Family Cancer Center
-
Independence, Ohio, Förenta staterna, 44131
- Cleveland Clinic Cancer Center Independence
-
Kettering, Ohio, Förenta staterna, 45429
- Kettering Medical Center
-
Kettering, Ohio, Förenta staterna, 45409
- Greater Dayton Cancer Center
-
Lima, Ohio, Förenta staterna, 45801
- Saint Rita's Medical Center
-
Mansfield, Ohio, Förenta staterna, 44906
- Cleveland Clinic Cancer Center Mansfield
-
Marietta, Ohio, Förenta staterna, 45750
- Marietta Memorial Hospital
-
Marion, Ohio, Förenta staterna, 43302
- OhioHealth Marion General Hospital
-
Maumee, Ohio, Förenta staterna, 43537
- Toledo Clinic Cancer Centers-Maumee
-
Maumee, Ohio, Förenta staterna, 43537
- Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
-
Mayfield Heights, Ohio, Förenta staterna, 44124
- Hillcrest Hospital Cancer Center
-
Mentor, Ohio, Förenta staterna, 44060
- UH Seidman Cancer Center at Lake Health Mentor Campus
-
Middleburg Heights, Ohio, Förenta staterna, 44130
- UH Seidman Cancer Center at Southwest General Hospital
-
Mount Vernon, Ohio, Förenta staterna, 43050
- Knox Community Hospital
-
Newark, Ohio, Förenta staterna, 43055
- Licking Memorial Hospital
-
Oregon, Ohio, Förenta staterna, 43616
- Saint Charles Hospital
-
Parma, Ohio, Förenta staterna, 44129
- University Hospitals Parma Medical Center
-
Perrysburg, Ohio, Förenta staterna, 43551
- Mercy Health - Perrysburg Hospital
-
Portsmouth, Ohio, Förenta staterna, 45662
- Southern Ohio Medical Center
-
Sandusky, Ohio, Förenta staterna, 44870
- North Coast Cancer Care
-
Sandusky, Ohio, Förenta staterna, 44870
- UH Seidman Cancer Center at Firelands Regional Medical Center
-
Springfield, Ohio, Förenta staterna, 45504
- Springfield Regional Cancer Center
-
Springfield, Ohio, Förenta staterna, 45504
- Springfield Regional Medical Center
-
Strongsville, Ohio, Förenta staterna, 44136
- Cleveland Clinic Cancer Center Strongsville
-
Sylvania, Ohio, Förenta staterna, 43560
- ProMedica Flower Hospital
-
Toledo, Ohio, Förenta staterna, 43623
- Mercy Health - Saint Anne Hospital
-
Toledo, Ohio, Förenta staterna, 43623
- Toledo Clinic Cancer Centers-Toledo
-
Toledo, Ohio, Förenta staterna, 43614
- University of Toledo
-
Wadsworth, Ohio, Förenta staterna, 44281
- University Hospitals Sharon Health Center
-
Warrensville Heights, Ohio, Förenta staterna, 44122
- South Pointe Hospital
-
Westlake, Ohio, Förenta staterna, 44145
- UH Seidman Cancer Center at Saint John Medical Center
-
Wooster, Ohio, Förenta staterna, 44691
- Cleveland Clinic Wooster Family Health and Surgery Center
-
Wright-Patterson Air Force Base, Ohio, Förenta staterna, 45433
- Wright-Patterson Medical Center
-
Zanesville, Ohio, Förenta staterna, 43701
- Genesis Healthcare System Cancer Care Center
-
-
Oklahoma
-
Lawton, Oklahoma, Förenta staterna, 73505
- Cancer Centers of Southwest Oklahoma Research
-
Oklahoma City, Oklahoma, Förenta staterna, 73104
- University of Oklahoma Health Sciences Center
-
Oklahoma City, Oklahoma, Förenta staterna, 73120
- Mercy Hospital Oklahoma City
-
-
Oregon
-
Clackamas, Oregon, Förenta staterna, 97015
- Providence Cancer Institute Clackamas Clinic
-
Coos Bay, Oregon, Förenta staterna, 97420
- Bay Area Hospital
-
Corvallis, Oregon, Förenta staterna, 97330
- Good Samaritan Hospital
-
Grants Pass, Oregon, Förenta staterna, 97527
- Three Rivers Community Hospital
-
Medford, Oregon, Förenta staterna, 97504
- Providence Medford Medical Center
-
Medford, Oregon, Förenta staterna, 97504
- Asante Rogue Regional Medical Center
-
Newberg, Oregon, Förenta staterna, 97132
- Providence Newberg Medical Center
-
Ontario, Oregon, Förenta staterna, 97914
- Saint Alphonsus Cancer Care Center-Ontario
-
Portland, Oregon, Förenta staterna, 97213
- Providence Portland Medical Center
-
Portland, Oregon, Förenta staterna, 97225
- Providence Saint Vincent Medical Center
-
Portland, Oregon, Förenta staterna, 97227
- Kaiser Permanente Northwest
-
-
Pennsylvania
-
Allentown, Pennsylvania, Förenta staterna, 18103
- Lehigh Valley Hospital-Cedar Crest
-
Bethlehem, Pennsylvania, Förenta staterna, 18017
- Lehigh Valley Hospital - Muhlenberg
-
Bethlehem, Pennsylvania, Förenta staterna, 18015
- Saint Luke's University Hospital-Bethlehem Campus
-
Broomall, Pennsylvania, Förenta staterna, 19008
- Crozer-Keystone Regional Cancer Center at Broomall
-
Bryn Mawr, Pennsylvania, Förenta staterna, 19010
- Bryn Mawr Hospital
-
Danville, Pennsylvania, Förenta staterna, 17822
- Geisinger Medical Center
-
Ephrata, Pennsylvania, Förenta staterna, 17522
- Ephrata Cancer Center
-
Ephrata, Pennsylvania, Förenta staterna, 17522
- Ephrata Community Hospital
-
Erie, Pennsylvania, Förenta staterna, 16505
- UPMC Hillman Cancer Center Erie
-
Gettysburg, Pennsylvania, Förenta staterna, 17325
- Adams Cancer Center
-
Harrisburg, Pennsylvania, Förenta staterna, 17109
- UPMC Pinnacle Cancer Center/Community Osteopathic Campus
-
Hazleton, Pennsylvania, Förenta staterna, 18201
- Geisinger Medical Center-Cancer Center Hazleton
-
Hershey, Pennsylvania, Förenta staterna, 17033-0850
- Penn State Milton S Hershey Medical Center
-
Lebanon, Pennsylvania, Förenta staterna, 17042
- Sechler Family Cancer Center
-
Lewisburg, Pennsylvania, Förenta staterna, 17837
- Geisinger Medical Oncology-Lewisburg
-
Lewistown, Pennsylvania, Förenta staterna, 17044
- Lewistown Hospital
-
Media, Pennsylvania, Förenta staterna, 19063
- Riddle Memorial Hospital
-
Paoli, Pennsylvania, Förenta staterna, 19301
- Paoli Memorial Hospital
-
Philadelphia, Pennsylvania, Förenta staterna, 19111
- Fox Chase Cancer Center
-
Philadelphia, Pennsylvania, Förenta staterna, 19107
- Thomas Jefferson University Hospital
-
Philadelphia, Pennsylvania, Förenta staterna, 19104
- University of Pennsylvania/Abramson Cancer Center
-
Philadelphia, Pennsylvania, Förenta staterna, 19140
- Temple University Hospital
-
Pittsburgh, Pennsylvania, Förenta staterna, 15232
- UPMC Hillman Cancer Center
-
Pottsville, Pennsylvania, Förenta staterna, 17901
- Geisinger Cancer Services-Pottsville
-
Reading, Pennsylvania, Förenta staterna, 19605
- Penn State Health Saint Joseph Medical Center
-
Sayre, Pennsylvania, Förenta staterna, 18840
- Guthrie Medical Group PC-Robert Packer Hospital
-
Scranton, Pennsylvania, Förenta staterna, 18510
- Community Medical Center
-
State College, Pennsylvania, Förenta staterna, 16801
- Geisinger Medical Group
-
State College, Pennsylvania, Förenta staterna, 16803
- Mount Nittany Medical Center
-
West Chester, Pennsylvania, Förenta staterna, 19380
- Chester County Hospital
-
West Reading, Pennsylvania, Förenta staterna, 19611
- Reading Hospital
-
Wilkes-Barre, Pennsylvania, Förenta staterna, 18711
- Geisinger Wyoming Valley/Henry Cancer Center
-
Williamsport, Pennsylvania, Förenta staterna, 17701
- UPMC Susquehanna
-
Willow Grove, Pennsylvania, Förenta staterna, 19090
- Asplundh Cancer Pavilion
-
Wynnewood, Pennsylvania, Förenta staterna, 19096
- Lankenau Medical Center
-
York, Pennsylvania, Förenta staterna, 17403
- WellSpan Health-York Cancer Center
-
York, Pennsylvania, Förenta staterna, 17403
- WellSpan Health-York Hospital
-
-
Rhode Island
-
Providence, Rhode Island, Förenta staterna, 02908
- Roger Williams Medical Center
-
-
South Carolina
-
Boiling Springs, South Carolina, Förenta staterna, 29316
- Prisma Health Cancer Institute - Spartanburg
-
Charleston, South Carolina, Förenta staterna, 29425
- Medical University of South Carolina
-
Easley, South Carolina, Förenta staterna, 29640
- Prisma Health Cancer Institute - Easley
-
Florence, South Carolina, Förenta staterna, 29506
- McLeod Regional Medical Center
-
Gaffney, South Carolina, Förenta staterna, 29341
- Gibbs Cancer Center-Gaffney
-
Greenville, South Carolina, Förenta staterna, 29605
- Prisma Health Cancer Institute - Faris
-
Greenville, South Carolina, Förenta staterna, 29607
- Saint Francis Cancer Center
-
Greenville, South Carolina, Förenta staterna, 29615
- Prisma Health Cancer Institute - Eastside
-
Greenville, South Carolina, Förenta staterna, 29605
- Prisma Health Cancer Institute - Butternut
-
Greenville, South Carolina, Förenta staterna, 29601
- Saint Francis Hospital
-
Greenwood, South Carolina, Förenta staterna, 29646
- Self Regional Healthcare
-
Greer, South Carolina, Förenta staterna, 29650
- Prisma Health Cancer Institute - Greer
-
Greer, South Carolina, Förenta staterna, 29651
- Gibbs Cancer Center-Pelham
-
Hilton Head Island, South Carolina, Förenta staterna, 29926-3827
- South Carolina Cancer Specialists PC
-
Seneca, South Carolina, Förenta staterna, 29672
- Prisma Health Cancer Institute - Seneca
-
Spartanburg, South Carolina, Förenta staterna, 29303
- Spartanburg Medical Center
-
West Columbia, South Carolina, Förenta staterna, 29169
- Lexington Health
-
-
South Dakota
-
Sioux Falls, South Dakota, Förenta staterna, 57105
- Avera Cancer Institute
-
Sioux Falls, South Dakota, Förenta staterna, 57117-5134
- Sanford USD Medical Center - Sioux Falls
-
Sioux Falls, South Dakota, Förenta staterna, 57104
- Sanford Cancer Center Oncology Clinic
-
-
Tennessee
-
Bristol, Tennessee, Förenta staterna, 37620
- Bristol Regional Medical Center
-
Cookeville, Tennessee, Förenta staterna, 38501
- Cookeville Regional Medical Center
-
Johnson City, Tennessee, Förenta staterna, 37604
- Wellmont Medical Associates Oncology and Hematology-Johnson City
-
Kingsport, Tennessee, Förenta staterna, 37660
- Ballad Health Cancer Care - Kingsport
-
Kingsport, Tennessee, Förenta staterna, 37660
- Wellmont Holston Valley Hospital and Medical Center
-
Memphis, Tennessee, Förenta staterna, 38120
- Baptist Memorial Hospital and Cancer Center-Memphis
-
Memphis, Tennessee, Förenta staterna, 38120
- Baptist Memorial Hospital for Women
-
Memphis, Tennessee, Förenta staterna, 38120
- Family Cancer Center-Memphis
-
Nashville, Tennessee, Förenta staterna, 37232
- Vanderbilt University/Ingram Cancer Center
-
-
Texas
-
Abilene, Texas, Förenta staterna, 79601
- Hendrick Medical Center
-
Amarillo, Texas, Förenta staterna, 79106
- The Don and Sybil Harrington Cancer Center
-
Austin, Texas, Förenta staterna, 78701
- Dell Seton Medical Center at The University of Texas
-
Dallas, Texas, Förenta staterna, 75235
- Parkland Memorial Hospital
-
Dallas, Texas, Förenta staterna, 75390
- UT Southwestern/Simmons Cancer Center-Dallas
-
Fort Worth, Texas, Förenta staterna, 76104
- UT Southwestern/Simmons Cancer Center-Fort Worth
-
Houston, Texas, Förenta staterna, 77030
- UT MD Anderson Cancer Center
-
Houston, Texas, Förenta staterna, 77030
- Houston Methodist Hospital
-
Houston, Texas, Förenta staterna, 77030
- Memorial Hermann Texas Medical Center
-
League City, Texas, Förenta staterna, 77573
- UT MD Anderson - League City
-
Lubbock, Texas, Förenta staterna, 79410
- Covenant Medical Center-Lakeside
-
Sugar Land, Texas, Förenta staterna, 77479
- Houston Methodist Sugar Land Hospital
-
-
Utah
-
American Fork, Utah, Förenta staterna, 84003
- American Fork Hospital / Huntsman Intermountain Cancer Center
-
Cedar City, Utah, Förenta staterna, 84720
- Sandra L Maxwell Cancer Center
-
Murray, Utah, Förenta staterna, 84107
- Intermountain Medical Center
-
Ogden, Utah, Förenta staterna, 84403
- McKay-Dee Hospital Center
-
Provo, Utah, Förenta staterna, 84604
- Utah Valley Regional Medical Center
-
Salt Lake City, Utah, Förenta staterna, 84106
- Utah Cancer Specialists-Salt Lake City
-
Salt Lake City, Utah, Förenta staterna, 84143
- LDS Hospital
-
St. George, Utah, Förenta staterna, 84770
- Saint George Regional Medical Center
-
-
Vermont
-
Bennington, Vermont, Förenta staterna, 05201
- Southwestern Vermont Medical Center
-
Berlin Corners, Vermont, Förenta staterna, 05602
- Central Vermont Medical Center/National Life Cancer Treatment
-
Burlington, Vermont, Förenta staterna, 05401
- University of Vermont Medical Center
-
Burlington, Vermont, Förenta staterna, 05405
- University of Vermont and State Agricultural College
-
-
Virginia
-
Bristol, Virginia, Förenta staterna, 24201
- Ballad Health Cancer Care - Bristol
-
Charlottesville, Virginia, Förenta staterna, 22908
- University of Virginia Cancer Center
-
Charlottesville, Virginia, Förenta staterna, 22911
- Sentara Martha Jefferson Hospital
-
Fairfax, Virginia, Förenta staterna, 22031
- Inova Schar Cancer Institute
-
Fairfax, Virginia, Förenta staterna, 22033
- Inova Fair Oaks Hospital
-
Falls Church, Virginia, Förenta staterna, 22042
- Inova Fairfax Hospital
-
Fishersville, Virginia, Förenta staterna, 22939
- Augusta Health Center for Cancer and Blood Disorders
-
Fredericksburg, Virginia, Förenta staterna, 22408
- Hematology Oncology Associates of Fredericksburg Inc
-
Fredericksburg, Virginia, Förenta staterna, 22401
- Mary Washington Hospital
-
Lynchburg, Virginia, Förenta staterna, 24501
- Centra Alan B Pearson Regional Cancer Center
-
Martinsville, Virginia, Förenta staterna, 24112
- Sovah Health Martinsville
-
Mechanicsville, Virginia, Förenta staterna, 23116
- Bon Secours Memorial Regional Medical Center
-
Midlothian, Virginia, Förenta staterna, 23114
- Bon Secours Saint Francis Medical Center
-
Norton, Virginia, Förenta staterna, 24273
- Ballad Health Cancer Care - Norton
-
Richmond, Virginia, Förenta staterna, 23229
- Virginia Cancer Institute
-
Richmond, Virginia, Förenta staterna, 23226
- Bon Secours Saint Mary's Hospital
-
Richmond, Virginia, Förenta staterna, 23298
- VCU Massey Comprehensive Cancer Center
-
South Hill, Virginia, Förenta staterna, 23970
- VCU Community Memorial Health Center
-
-
Washington
-
Aberdeen, Washington, Förenta staterna, 98520
- Providence Regional Cancer System-Aberdeen
-
Centralia, Washington, Förenta staterna, 98531
- Providence Regional Cancer System-Centralia
-
Edmonds, Washington, Förenta staterna, 98026
- Swedish Cancer Institute-Edmonds
-
Issaquah, Washington, Förenta staterna, 98029
- Swedish Cancer Institute-Issaquah
-
Kirkland, Washington, Förenta staterna, 98034
- FHCC at EvergreenHealth
-
Lacey, Washington, Förenta staterna, 98503
- Providence Regional Cancer System-Lacey
-
Poulsbo, Washington, Förenta staterna, 98370
- Harrison HealthPartners Hematology and Oncology-Poulsbo
-
Renton, Washington, Förenta staterna, 98055
- Valley Medical Center
-
Seattle, Washington, Förenta staterna, 98101
- Virginia Mason Medical Center
-
Seattle, Washington, Förenta staterna, 98122
- Swedish Medical Center-First Hill
-
Seattle, Washington, Förenta staterna, 98195
- University of Washington Medical Center - Montlake
-
Seattle, Washington, Förenta staterna, 98109
- Fred Hutchinson Cancer Center
-
Silverdale, Washington, Förenta staterna, 98383
- Saint Joseph Medical Center Hematology and Oncology - Silverdale
-
Tacoma, Washington, Förenta staterna, 98405
- MultiCare Tacoma General Hospital
-
Vancouver, Washington, Förenta staterna, 98664
- PeaceHealth Southwest Medical Center
-
Walla Walla, Washington, Förenta staterna, 99362
- Providence Saint Mary Regional Cancer Center
-
-
West Virginia
-
Bridgeport, West Virginia, Förenta staterna, 26330
- United Hospital Center
-
Charleston, West Virginia, Förenta staterna, 25304
- Vandalia Health/CAMC Institute for Academic Medicine
-
Huntington, West Virginia, Förenta staterna, 25701
- Edwards Comprehensive Cancer Center
-
Morgantown, West Virginia, Förenta staterna, 26506
- West Virginia University Healthcare
-
-
Wisconsin
-
Antigo, Wisconsin, Förenta staterna, 54409
- Aspirus Cancer Care-Antigo-Volm Cancer Center
-
Appleton, Wisconsin, Förenta staterna, 54911
- ThedaCare Regional Cancer Center
-
Appleton, Wisconsin, Förenta staterna, 54915
- Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton
-
Ashland, Wisconsin, Förenta staterna, 54806
- Duluth Clinic Ashland
-
Brookfield, Wisconsin, Förenta staterna, 53045
- Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield
-
Burlington, Wisconsin, Förenta staterna, 53105
- Aurora Cancer Care-Southern Lakes VLCC
-
Chippewa Falls, Wisconsin, Förenta staterna, 54729
- Marshfield Clinic-Chippewa Center
-
Eau Claire, Wisconsin, Förenta staterna, 54701
- Marshfield Medical Center-EC Cancer Center
-
Eau Claire, Wisconsin, Förenta staterna, 54701
- Marshfield Clinic Cancer Center at Sacred Heart
-
Fond du Lac, Wisconsin, Förenta staterna, 54937
- Aurora Health Center-Fond du Lac
-
Franklin, Wisconsin, Förenta staterna, 53132
- Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson
-
Germantown, Wisconsin, Förenta staterna, 53022
- Aurora Health Care Germantown Health Center
-
Grafton, Wisconsin, Förenta staterna, 53024
- Aurora Cancer Care-Grafton
-
Green Bay, Wisconsin, Förenta staterna, 54311
- Aurora BayCare Medical Center
-
Green Bay, Wisconsin, Förenta staterna, 54301
- Saint Vincent Hospital Cancer Center Green Bay
-
Green Bay, Wisconsin, Förenta staterna, 54303
- Saint Vincent Hospital Cancer Center at Saint Mary's
-
Johnson Creek, Wisconsin, Förenta staterna, 53038
- University of Wisconsin Carbone Cancer Center - Johnson Creek
-
Kenosha, Wisconsin, Förenta staterna, 53142
- Aurora Cancer Care-Kenosha South
-
La Crosse, Wisconsin, Förenta staterna, 54601
- Gundersen Lutheran Medical Center
-
Ladysmith, Wisconsin, Förenta staterna, 54848
- Marshfield Medical Center - Ladysmith
-
Madison, Wisconsin, Förenta staterna, 53705
- William S Middleton VA Medical Center
-
Madison, Wisconsin, Förenta staterna, 53792
- University of Wisconsin Carbone Cancer Center - University Hospital
-
Manitowoc, Wisconsin, Förenta staterna, 54221
- Holy Family Memorial Hospital
-
Marinette, Wisconsin, Förenta staterna, 54143
- Aurora Bay Area Medical Group-Marinette
-
Marinette, Wisconsin, Förenta staterna, 54143
- Saint Vincent Hospital Cancer Center at Marinette
-
Marshfield, Wisconsin, Förenta staterna, 54449
- Marshfield Medical Center-Marshfield
-
Mequon, Wisconsin, Förenta staterna, 53097
- Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon
-
Milwaukee, Wisconsin, Förenta staterna, 53226
- Medical College of Wisconsin
-
Milwaukee, Wisconsin, Förenta staterna, 53209
- Aurora Cancer Care-Milwaukee
-
Milwaukee, Wisconsin, Förenta staterna, 53215
- Aurora Saint Luke's Medical Center
-
Milwaukee, Wisconsin, Förenta staterna, 53233
- Aurora Sinai Medical Center
-
Milwaukee, Wisconsin, Förenta staterna, 53211
- Ascension Columbia Saint Mary's Hospital-Milwaukee Campus
-
Minocqua, Wisconsin, Förenta staterna, 54548
- Marshfield Medical Center - Minocqua
-
Mukwonago, Wisconsin, Förenta staterna, 53149
- ProHealth D N Greenwald Center
-
New Richmond, Wisconsin, Förenta staterna, 54017
- Cancer Center of Western Wisconsin
-
Oconomowoc, Wisconsin, Förenta staterna, 53066
- ProHealth Oconomowoc Memorial Hospital
-
Oconto Falls, Wisconsin, Förenta staterna, 54154
- Saint Vincent Hospital Cancer Center at Oconto Falls
-
Oshkosh, Wisconsin, Förenta staterna, 54904
- Vince Lombardi Cancer Clinic - Oshkosh
-
Oshkosh, Wisconsin, Förenta staterna, 54904
- Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh
-
Racine, Wisconsin, Förenta staterna, 53406
- Aurora Cancer Care-Racine
-
Rice Lake, Wisconsin, Förenta staterna, 54868
- Marshfield Medical Center-Rice Lake
-
Sheboygan, Wisconsin, Förenta staterna, 53081
- Vince Lombardi Cancer Clinic-Sheboygan
-
Sheboygan, Wisconsin, Förenta staterna, 53081
- HSHS Saint Nicholas Hospital
-
Stevens Point, Wisconsin, Förenta staterna, 54481
- Aspirus Cancer Care - Stevens Point
-
Sturgeon Bay, Wisconsin, Förenta staterna, 54235-1495
- Saint Vincent Hospital Cancer Center at Sturgeon Bay
-
Summit, Wisconsin, Förenta staterna, 53066
- Aurora Medical Center in Summit
-
Two Rivers, Wisconsin, Förenta staterna, 54241
- Vince Lombardi Cancer Clinic-Two Rivers
-
Waukesha, Wisconsin, Förenta staterna, 53188
- UW Cancer Center at ProHealth Care
-
Wausau, Wisconsin, Förenta staterna, 54401
- Marshfield Clinic-Wausau Center
-
Wausau, Wisconsin, Förenta staterna, 54401
- Aspirus Cancer Care-Wausau
-
Wauwatosa, Wisconsin, Förenta staterna, 53226
- Aurora Cancer Care-Milwaukee West
-
Wauwatosa, Wisconsin, Förenta staterna, 53226
- Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa
-
West Allis, Wisconsin, Förenta staterna, 53227
- Aurora West Allis Medical Center
-
Weston, Wisconsin, Förenta staterna, 54476
- Marshfield Medical Center - Weston
-
Wisconsin Rapids, Wisconsin, Förenta staterna, 54494
- Aspirus Cancer Care - Wisconsin Rapids
-
Wisconsin Rapids, Wisconsin, Förenta staterna, 54494
- Marshfield Clinic - Wisconsin Rapids Center
-
-
Wyoming
-
Cody, Wyoming, Förenta staterna, 82414
- Big Horn Basin Cancer Center
-
Cody, Wyoming, Förenta staterna, 82414
- Billings Clinic-Cody
-
Sheridan, Wyoming, Förenta staterna, 82801
- Welch Cancer Center
-
-
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
18 år och äldre (Vuxen, Äldre vuxen)
Tar emot friska volontärer
Nej
Kön som är behöriga för studier
Allt
Beskrivning
Inclusion Criteria:
-
Age >= 18 years
-
Patients must have undergone complete surgical resection of their stage IB (>= 4 cm), II or IIIA NSCLC according to the American Joint Committee on Cancer (AJCC) 7th edition and have had negative surgical margins
-
Baseline chest CT must be performed within 1 month (30 days) prior to randomization to ensure no evidence of disease; if clinically indicated, additional imaging studies must be performed to rule out metastatic disease
-
Eastern Cooperative Oncology Group (ECOG) performance status 0-1
-
Patients must be registered to the ALCHEMIST-SCREEN (ALLIANCE A151216) trial prior to randomization
-
Non-squamous tumors must not be positive for EGFR exon 19 deletion or exon 21 L858R mutation (centrally as part of the ALCHEMIST-SCREEN protocol) and ALK rearrangement (centrally as part of ALCHEMIST-SCREEN and/or locally)
- NOTE: if the results of the central EGFR testing are negative, but the ALK testing was not able to be completed by the ALCHEMIST central lab, the ALK status will be considered negative (unless locally positive for ALK rearrangement) and the patient may be considered for enrollment onto EA5142, once PD-L1 results are received and all other eligibility requirements are met
-
Tumors must have PD-L1 status tested centrally as part of the ALCHEMIST-SCREEN protocol
-
Women must not be pregnant or breast-feeding due to unknown and potentially harmful effects of nivolumab on the developing fetus or child
-
All females of childbearing potential must have a blood test or urine study within 2 weeks prior to registration to rule out pregnancy; a female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
-
Women of childbearing potential and sexually active males must be strongly advised to use an accepted and effective method of contraception or to abstain from sexual intercourse during the treatment period and for 31 weeks after the last nivolumab infusion
-
Patients must NOT have uncontrolled intercurrent illness including, but not limited to, serious ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, uncontrolled cardiac arrhythmia, or psychiatric illness/social situation that would limit compliance with study requirements
-
No prior treatment with an immune checkpoint inhibitor (anti-PD-1, anti-PD-L1, anti-CTLA4 monoclonal antibody)
-
Patients must have adequately recovered from thoracic surgery and any administered chemotherapy/radiotherapy at the time of randomization (NOTE: adjuvant chemotherapy and/or radiation is not required)
-
Minimum time between date of surgery and randomization is 4 weeks (28 days)
-
Maximum time allowed between surgery and randomization:
- 3 months (90 days) if no chemotherapy is administered
- 8 months (240 days) if adjuvant chemotherapy was administered
- 10 months (300 days) if adjuvant chemotherapy and radiation therapy was administered
-
-
Patients must have completed and recovered from any adjuvant chemotherapy 2 or more weeks prior to randomization (6 weeks for mitomycin and nitrosoureas; 4 weeks for post-operative radiation therapy) (NOTE: adjuvant chemotherapy and/or radiation is not required)
-
Serum aspartate transaminase (aspartate aminotransferase [AST]) and serum alanine transaminase (alanine aminotransferase [ALT]) =< 2.5 x upper limit normal (within 2 weeks prior to randomization)
-
Total bilirubin =< 1.5 x upper limit of normal (ULN) (except in subjects with Gilbert syndrome who must have a total bilirubin < 3.0 x ULN) (within 2 weeks prior to randomization)
-
White blood cell (WBC) >= 2000/uL (within 2 weeks prior to randomization)
-
Neutrophils >= 1000/uL (within 2 weeks prior to randomization)
-
Platelets >= 100 x 10^3/uL (within 2 weeks prior to randomization)
-
Hemoglobin >= 8 g/dL (within 2 weeks prior to randomization)
-
Serum creatinine =< 2 x ULN (within 2 weeks prior to randomization)
-
Prior to randomization patients with any non-hematologic toxicity from surgery, chemotherapy and radiation therapy must have recovered to grade =< 1 with the exception of alopecia, ototoxicity and neuropathy
-
Patients must not be receiving any other investigational anti-cancer agents while on study
-
Patients must not have known or suspected autoimmune disease; subjects with type I diabetes mellitus, hypothyroidism requiring hormone replacement, or skin disorders not requiring systemic treatment are permitted to enroll
-
Patients must not have a condition requiring systemic corticosteroids equivalent to > 10 mg prednisone per day or other immunosuppressive medications within 2 weeks of randomization; inhaled, intra-articular, and epidural steroids are permissible
-
Patients must not have known interstitial lung disease that is symptomatic or may interfere with the detection or management of suspected drug-related pulmonary toxicity
-
Patients must not have a known history of human immunodeficiency virus (HIV), hepatitis B, or hepatitis C infection that is untreated and/or with a detectable viral load
-
Patients must not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition to nivolumab
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: Randomiserad
- Interventionsmodell: Parallellt uppdrag
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
|
Experimentell: Arm I (nivolumab)
Patients receive nivolumab IV over 30 minutes on day 1 of each cycle. Cycles repeat every 4 weeks for up to 1 year in the absence of disease progression or unacceptable toxicity. Patients also undergo CT and/or PET/CT throughout the trial and blood sample collection during screening and follow-up. Patients may undergo an ECHO as clinically indicated on study. |
Undergo blood sample collection
Andra namn:
Undergo CT
Andra namn:
Undergo ECHO
Andra namn:
Given IV
Andra namn:
Undergo PET-CT
Andra namn:
|
|
Aktiv komparator: Arm II (observation)
Patients are followed serially with CT and/or PET/CT imaging for up to 1 year and then during follow-up. Patients also undergo blood sample collection during screening and follow-up. Patients may undergo an ECHO as clinically indicated on study. |
Undergo blood sample collection
Andra namn:
Undergo CT
Andra namn:
Undergo ECHO
Andra namn:
Undergo PET-CT
Andra namn:
Undergo observation
Andra namn:
|
Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Disease-free survival (DFS)
Tidsram: Time from randomization to the earliest event defined as disease recurrence, any new lung cancer (even in the opposite lung), or death from any cause at any known point in time, assessed up to 10 years
|
DFS distributions will be estimated using the Kaplan-Meier method, and Cox proportional hazards models will be used to estimate the treatment hazard ratios. The primary comparisons of DFS will use a logrank tests stratified on the randomization stratification factors with a one-sided type I error rate corresponding to the significance level associated with population being analyzed; that is, 1.5% for the overall population and 1% for the >= 50% population. The latter test will only be performed in the event that the primary test in all-comers is not statistically significant. Other comparisons of groups will be made using the logrank test and Cox modeling. Point estimates of all endpoints will be accompanied by the corresponding confidence intervals adjusted for the type I error rates associated with the endpoint. Subset analyses are planned for all stratification factors and all known prognostic factors such as performance status, age, gender, etc. |
Time from randomization to the earliest event defined as disease recurrence, any new lung cancer (even in the opposite lung), or death from any cause at any known point in time, assessed up to 10 years
|
|
Overall survival (OS)
Tidsram: From randomization to death from any cause, assessed up to 10 years
|
OS distributions will be estimated using the Kaplan-Meier method, and Cox proportional hazards models will be used to estimate the treatment hazard ratios. The primary comparisons of OS will use a logrank tests stratified on the randomization stratification factors with a one-sided type I error rate corresponding to the significance level associated with population being analyzed; that is, 1.5% for the overall population and 1% for the >= 50% population. The latter test will only be performed in the event that the primary test in all-comers is not statistically significant. Other comparisons of groups will be made using the logrank test and Cox modeling. Point estimates of all endpoints will be accompanied by the corresponding confidence intervals adjusted for the type I error rates associated with the endpoint. Subset analyses are planned for all stratification factors and all known prognostic factors such as performance status, age, gender, etc. |
From randomization to death from any cause, assessed up to 10 years
|
Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Incidence of adverse events
Tidsram: Up to 10 years
|
Toxicity graded according to Common Terminology Criteria for Adverse Events version 5.0. Toxicity rates will be compared using Fisher's exact tests with a one-sided type I error rate of 2.5%; multivariable logistic regression modeling will be used to adjust for the effect of any covariates that are associated with these categorical outcomes. Point estimates of all endpoints will be accompanied by the corresponding confidence intervals adjusted for the type I error rates associated with the endpoint. Subset analyses are planned for all stratification factors and all known prognostic factors such as performance status, age, gender, etc. |
Up to 10 years
|
Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Utredare
- Huvudutredare: Jamie E Chaft, ECOG-ACRIN Cancer Research Group
Publikationer och användbara länkar
Den som ansvarar för att lägga in information om studien tillhandahåller frivilligt dessa publikationer. Dessa kan handla om allt som har med studien att göra.
Allmänna publikationer
- Frumm SM, Florez N, Lee JM, Rotow JK, Chaft JE. Updates on the Perioperative Management of Resectable Non-Small Cell Lung Cancer. J Natl Compr Canc Netw. 2026 Mar 24;24(4):e267005. doi: 10.6004/jnccn.2026.7005.
- Chaft JE, Sun Z, Rudin CM, Khullar OV, Simone CB 2nd, Oettel K, Kozono D, Sunkara R, Faller B, Isbell JM, Hugec V, Shipstone A, McGary EC, Clarke JM, Talsania A, Ding L, Govindan R, Sands JM, Heymach JV, Raez LE, Malik SM, Stinchcombe TE, Mandrekar SJ, Bradley J, Gerber DE, Vokes E, Gandara D, Staley C, Ramalingam SS. Adjuvant Nivolumab vs Observation in Resected Non-Small Cell Lung Cancer: A Randomized Clinical Trial. JAMA. 2026 Aug 11;336(6):464-472. doi: 10.1001/jama.2026.8992.
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Faktisk)
22 juli 2016
Primärt slutförande (Beräknad)
31 maj 2027
Avslutad studie (Beräknad)
31 maj 2027
Studieregistreringsdatum
Först inskickad
3 november 2015
Först inskickad som uppfyllde QC-kriterierna
3 november 2015
Första postat (Beräknad)
4 november 2015
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
12 november 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
11 november 2026
Senast verifierad
1 september 2026
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
- Neoplasmer efter plats
- Neoplasmer
- Luftvägssjukdomar
- Lungsjukdomar
- Neoplasmer i andningsvägarna
- Thoracic neoplasmer
- Lungneoplasmer
- Karcinom, bronkogent
- Bronkiella neoplasmer
- Karcinom, icke-småcellig lunga
- Aminosyror, peptider och proteiner
- Proteiner
- Undersökningstekniker
- Metoder
- Kliniska laboratorietekniker
- Diagnostiska tekniker och procedurer
- Diagnos
- Antikroppar, monoklonal, humaniserad
- Antikroppar, monoklonal
- Antikroppar
- Immunglobuliner
- Immunoproteiner
- Blodproteiner
- Serumglobuliner
- Globuliner
- Kemitekniker, analytiska
- Spektrumanalys
- Nivolumab
- Observation
- Provhantering
- Magnetresonansspektroskopi
Andra studie-ID-nummer
- NCI-2015-01916
- U10CA180820 (U.S.S. NIH-anslag/kontrakt)
- NCI-2015-01916 (Registeridentifierare: CTRP (Clinical Trial Reporting Program))
- EA5142 (Annan identifierare: CTEP)
- s16-02074
- EA5142 (Annan identifierare: ECOG-ACRIN Cancer Research Group)
Denna information hämtades direkt från webbplatsen clinicaltrials.gov utan några ändringar. Om du har några önskemål om att ändra, ta bort eller uppdatera dina studieuppgifter, vänligen kontakta register@clinicaltrials.gov. Så snart en ändring har implementerats på clinicaltrials.gov, kommer denna att uppdateras automatiskt även på vår webbplats .