The Effects of a Multicomponent Sleep & Recovery Supplement on Muscle Fatigue and Sleep
5 augusti 2026 uppdaterad av: University of Exeter
The Effects of a Multicomponent Sleep & Recovery Supplement on Exercise Performance and Recovery Following a Muscle Damaging Protocol
The goal of this clinical trial (randomised crossover study) is to learn if a multi-component sleep and exercise recovery supplement can improve sleep quality and enhance recovery following exercise in healthy, recreationally active adults aged 18-40.
The main questions it aims to answer are:
- Does the supplement reduce delayed onset muscle soreness (DOMS) following an intense exercise protocol?
- Does the supplement improve sleep quality?
Researchers will compare the supplement to a placebo (a look-alike tablet with no active ingredients) to see if the supplement improves exercise recovery and sleep quality. In this crossover design, all participants will receive both the supplement and the placebo in separate 2-week periods, with a 2-week washout period in between.
Participants will:
- Take the supplement during one 2-week period and the placebo during another (order randomised), 30 minutes before bed each day
- Complete an exercise protocol involving repeated leg extensions designed to induce muscle fatigue
- Attend six laboratory visits, including baseline testing and follow-up assessments at 24 and 48 hours post-exercise
- Complete daily sleep questionnaires during each supplementation period
- Record food intake prior to exercise trials and replicate it for consistency
- Perform muscle soreness assessments and single-leg jump tests before and after exercise, and during recovery
Studieöversikt
Status
Har inte rekryterat ännu
Intervention / Behandling
Studietyp
Interventionell
Inskrivning (Beräknad)
25
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studiekontakt
- Namn: Tom G Gurney, PhD
- Telefonnummer: +44 (0) 1326 370400
- E-post: t.g.gurney@exeter.ac.uk
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
- Vuxen
Tar emot friska volontärer
Ja
Beskrivning
Inclusion Criteria:
- Aged between 18-40, healthy and non smokers
- Recreationally active, exercise at least 2 times a week
Exclusion Criteria:
• Not have any injuries that would affect performance
- Not taking any medications that could affect drowsiness or energy levels
- Not taking any other dietary supplements high in magnesium
- Not be pregnant
- Not have any illness or medical condition that could make intense exercise unsafe
- Not be participating in other studies that could interfere with the outcomes of this study
- Not have any current sleep problems e.g. Insomnia
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: Randomiserad
- Interventionsmodell: Crossover tilldelning
- Maskning: Dubbel
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
|
Experimentell: Magnesium-based sleep & recovery supplementation
Supplementation of a magnesium-based sleep & recovery supplement (2g/day for 2-weeks)
|
magnesium-based sleep & recovery supplement (2g/day for 2-weeks)
|
|
Placebo-jämförare: Placebo Supplementation
Supplementation of placebo (2g/day for 2-weeks)
|
Placebo Supplementation (2g/day for 2-weeks)
|
Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Changes in total work done
Tidsram: Following each 2-week supplementation period of either supplement
|
Changes in total work done as measured by the Biodex
|
Following each 2-week supplementation period of either supplement
|
|
Changes in work done (Flexion)
Tidsram: Following each 2-week supplementation period of either supplement
|
Changes in work done (Flexion) as measured by the Biodex
|
Following each 2-week supplementation period of either supplement
|
|
Changes in work done (Extension)
Tidsram: Following each 2-week supplementation period of either supplement
|
Changes in work done (Extension) as measured by the Biodex
|
Following each 2-week supplementation period of either supplement
|
|
Changes in Single Leg jump height
Tidsram: Before and Immediately After Muscle Damaging Protocol at the End of Each 2-Week Supplementation Period
|
Changes in Single Leg jump height (m)
|
Before and Immediately After Muscle Damaging Protocol at the End of Each 2-Week Supplementation Period
|
|
Changes in Single Leg Jump hang time
Tidsram: Before and Immediately After Muscle Damaging Protocol at the End of Each 2-Week Supplementation Period
|
Changes in Single Leg Jump hang time (s)
|
Before and Immediately After Muscle Damaging Protocol at the End of Each 2-Week Supplementation Period
|
Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Changes in sleep quality
Tidsram: Following each 2-week supplementation period of either supplement.
|
Changes in sleep quality as measured by the Groningen Sleep Quality questionnaire where a lower score indicates better sleep quality.
|
Following each 2-week supplementation period of either supplement.
|
|
Changes in perceived muscle soreness (Pain pressure threshold)
Tidsram: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol.
|
Changes in perceived muscle soreness (Pain pressure threshold in Newtons) as measured by the muscle algometer where a higher score means a better outcome
|
Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol.
|
|
Change in Self-Reported Readiness to Train Score (5-Point Likert Scale)
Tidsram: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
|
Change in perceived readiness to train or compete assessed using a self-reported 5-point Likert scale, where 1 = not at all ready (extremely fatigued/sore) and 5 = completely ready (fresh, no limitations)
|
Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
|
|
Changes in Sleep Quality
Tidsram: Following each 2-week supplementation period of either supplement.
|
Changes in Sleep Quality as measured by the Consensus Sleep Diary.
|
Following each 2-week supplementation period of either supplement.
|
|
Change in perceived recovery status (10-Point Likert Scale)
Tidsram: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
|
Change in perceived readiness to train or compete assessed using a self-reported 10-point Likert scale, where 0 = very poorly recovered and 10 = fully recovered
|
Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
|
|
Change in perceived overall muscle soreness (10-Point Likert Scale)
Tidsram: Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
|
Change in perceived readiness to train or compete assessed using a self-reported 10-point Likert scale, where 0 = no soreness and 10 = worse soreness imaginable
|
Following each 2-week supplementation period of either supplement and 24hr and 48hr following the muscle damaging protocol
|
Samarbetspartners och utredare
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Sponsor
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Beräknad)
1 augusti 2026
Primärt slutförande (Beräknad)
1 oktober 2026
Avslutad studie (Beräknad)
1 december 2026
Studieregistreringsdatum
Först inskickad
16 april 2026
Först inskickad som uppfyllde QC-kriterierna
5 augusti 2026
Första postat (Faktisk)
10 augusti 2026
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
10 augusti 2026
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
5 augusti 2026
Senast verifierad
1 augusti 2026
Mer information
Termer relaterade till denna studie
Nyckelord
Andra studie-ID-nummer
- 8096200
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- STUDY_PROTOCOL
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