Cell-Wave Study: Combined Extracorporal Shock Wave Therapy and Intracoronary Cell Therapy in Chronic Ischemic Myocardium

Inclusion Criteria:

• Patients with chronic ischemic heart disease
• Patients with anterior myocardial infarction > 3months
• EF < 50% or NYHA II-IV
• Age 18-80
• Informed consent

Exclusion Criteria:

• Ventricular thrombus
• Infarct < 3 months.
• Active infection or fever
• Chronic inflammatory disease (e.g M. Crohn, Rheumatoid Arthritis)
• HIV Infection oder active Hepatitis
• Neoplastic disease w/o complete remission within 5 years
• Stroke < 3months
• Creatinine > 2 mg/dl
• Relevant Liver disease (GOT > twice the upper limit).
• Anemia (Hemoglobin <10 mg/dl)
• Thrombocytopenia < 100.000/µl
• Allergies to Aspirin, Clopidogrel, Heparin
• History of bleeding disorder
• History of coagulopathy
• Gastrointestinal Bleeding < 3 months
• Surgery or Trauma < 2 months
• Pregnancy
• Mental Retardation
• Participation in other clinical study < 1 month