The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Wheezing\Coughing Babies
2011年9月4日 更新者：Avigdor Mandelberg、Wolfson Medical Center
The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Asthmatic/Wheezing Babies Using Impedance and Wheezy Monitoring
GER and respiratory symptoms are both common phenomenon in children.
Both can coexist in the same patient by chance alone.
Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality.
Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises.
Both modalities will be recorded for 12-24 hours.
If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor and vice versa.
研究概览
详细说明
GER and respiratory symptoms are both common phenomenon in children.
Both can coexist in the same patient by chance alone.
Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality.
Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises.
Both modalities will be recorded for 12-24 hours.
If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor.However, If cough/wheeze precedes GER recordings it points to cough/wheeze being the possible precipitating factor.
The recordings will be investigated 1 minute before and one minute after each event.
研究类型
观察性的
注册 (实际的)
15
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
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Holon、以色列
- Wolfson Medical center and Sackler School of Medicine, Tel Aviv University, Tel
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
1个月 至 1年 (孩子)
接受健康志愿者
不
有资格学习的性别
全部
取样方法
概率样本
研究人群
We studied 23 consecutive Difficult to treat infants and children suspected of suffering from both RS and GER with chronic respiratory symptoms.
However, four dropted due to technical problems wiht the equipment.
In 19 patients We fully analyzed the respiratory sounds one minute during and one minute before and one minute after each GER episode, and in all parental markings of cough.
描述
Inclusion Criteria:
- Children 1 month - 18 years old
- Difficult to treat asthma
- Difficult to treat cough
- Difficult to treat other respiratory symptoms
Exclusion Criteria:
- Children on artificial ventilation
- Children not compliant with PH-Metria and/or WEEM
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 观测模型：仅案例
- 时间观点：预期
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
A
Babies and small children 1-24 months
|
loudspeaker recording (WEEM) is attached externally to the chest simultaneously with PH-Impedance.
|
|
B
Children 2-18 years old
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loudspeaker recording (WEEM) is attached externally to the chest simultaneously with PH-Impedance.
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 研究主任：Avigdor Mandelberg, MD、Edith Wolfson Medical Center, and Sackler School of Medicine, Tel Aviv University, Tel aviv
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始
2007年3月1日
初级完成 (实际的)
2011年3月1日
研究完成 (实际的)
2011年9月1日
研究注册日期
首次提交
2007年8月6日
首先提交符合 QC 标准的
2007年8月6日
首次发布 (估计)
2007年8月7日
研究记录更新
最后更新发布 (估计)
2011年9月7日
上次提交的符合 QC 标准的更新
2011年9月4日
最后验证
2011年9月1日
更多信息
与本研究相关的术语
其他研究编号
- 688 special
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