Mechanisms of Change, Motivation, and Treatment Outcome in Alcohol Dependence - Posttraumatic Stress Disorder
2014年1月28日 更新者:Scott F. Coffey、University of Mississippi Medical Center
Mechanisms of Change, Motivation, and Treatment Outcome in AD-PTSD
The purpose of this study is to test if provision of an effective psychotherapy for Post-traumatic Stress Disorder (PTSD), prolonged exposure, can be tolerated in alcohol dependent patients with PTSD and if it is associated with better treatment outcomes compared to an active control condition.
研究概览
地位
完全的
研究类型
介入性
注册 (实际的)
126
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习地点
-
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Mississippi
-
Jackson、Mississippi、美国、39216
- University of Mississippi Medical Center
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-
参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
18年 至 60年 (成人)
接受健康志愿者
不
有资格学习的性别
全部
描述
Inclusion Criteria:
- Current PTSD
- Current Alcohol Dependence
- at least one heavy drinking day in the past 60 days
Exclusion Criteria:
- Psychotic disorder
- Untreated bi-polar disorder
- benzodiazepine use
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的:Healthy lifestyles sessions
Healthy lifestyles sessions is a structured 9-12 session intervention that provides education about a variety of health-related topics.
Each therapy session was 50-60 minutes long.
Sessions included the provision of information, discussing participants' understanding of information, and answering questions about the information provided.
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实验性的:Trauma-focused exposure therapy
Trauma focused exposure therapy is a well-described cognitive-behavioral therapy that utilizes imaginal and in vivo exposure techniques to reduce the symptoms of posttraumatic stress disorder.
In addition to imaginal and iv vivo exposure techniques, in the current study patients were provided psychoeducation about posttraumatic stress disorder, a rationale for trauma focused exposure therapy, and were taught breathing retraining as a method to manage arousal associated with posttraumatic stress disorder.
Nine to 12 50-60 minutes sessions were provided.
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cognitive behavioral therapy for PTSD
其他名称:
|
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实验性的:Motivational enhancement + trauma-focused exposure therapy
A one session, 90 min.
trauma-focused motivational enhancement therapy session was provided prior to starting the trauma-focused exposure therapy.
Trauma focused exposure therapy is a well-described cognitive-behavioral therapy that utilizes imaginal and in vivo exposure techniques to reduce the symptoms of posttraumatic stress disorder.
In addition to imaginal and iv vivo exposure techniques, in the current study patients were provided psychoeducation about posttraumatic stress disorder, a rationale for trauma focused exposure therapy, and were taught breathing retraining as a method to manage arousal associated with posttraumatic stress disorder.
Nine to 12 50-60 minutes sessions were provided.
|
Cognitive behavioral therapy for PTSD
其他名称:
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Impact of Event Scale-Revised
大体时间:3-months posttreatment
|
The Impact of Event Scale-Revised is a 22-item self-report measure of posttraumatic stress disorder symptoms.
The total score for the Impact of Event Scale-Revised ranges from 0 to 88 with lower scores representing less severe symptoms of posttraumatic stress disorder and higher scores representing more severe symptoms of posttraumatic stress disorder.
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3-months posttreatment
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Timeline Follow Back
大体时间:3-months posttreatment
|
The timeline follow back is a measure of drug and alcohol consumption in the prior 90 days.
The timeline follow back is a calendar-based retrospective account of drug and alcohol consumption for a specified period of time (e.g., past 90 days).
One of the most commonly reported metrics of drug and alcohol consumption from this measure is percent days abstinent (PDA).
Percent days abstinent is simply the proportion of days for the specified period of time (e.g., 90 days) in which drugs or alcohol were not consumed.
Percent days abstinent can range from 0 to 100 with 0 representing no abstinence during a specified period of time (i.e., consumed alcohol every day) and 100 representing complete abstinence during a specified period of time.
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3-months posttreatment
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员:Scott F. Coffey, Ph.D.、University of Mississippi Medical Center
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始
2008年7月1日
初级完成 (实际的)
2012年1月1日
研究完成 (实际的)
2013年5月1日
研究注册日期
首次提交
2011年8月2日
首先提交符合 QC 标准的
2011年8月3日
首次发布 (估计)
2011年8月4日
研究记录更新
最后更新发布 (估计)
2014年3月10日
上次提交的符合 QC 标准的更新
2014年1月28日
最后验证
2014年1月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.