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Predictors of Postoperative Pain

2014年5月15日更新者：American University of Beirut Medical Center

Predictors of Postoperative Pain Following Abdominal Hysterectomy

The purpose of the study is to prove that pain scores generated from painful stimuli applied preoperatively may help identify the inter-individual variability in pain perception.

研究概览

地位

完全的

条件

术后疼痛

干预/治疗

设备：Thermal Sensory Analyzer (Senselab)

详细说明

Psychological factors and experimental pain models such as as electrical, pressure, heat, or cold stimuli have been identified as predictors of pain intensity and opioid consumption postoperatively. This study will investigate, in addition to the factors described above, the ability of pain scores generated from painful stimuli postoperatively in predicting postoperative pain.

研究类型

介入性

注册 (实际的)

阶段

不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习地点

黎巴嫩
- - Beirut、黎巴嫩
    - AUBMC
  - Beirut、黎巴嫩
    - American Unversity of Beirut Medical Center

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

35年至 65年 (成人、年长者)

接受健康志愿者

是的

有资格学习的性别

女性

描述

Inclusion Criteria:

Patients undergoing abdominal hysterectomy through a pfannenstiel incision
American Society of Anesthesiologists (ASA)Class I-III

Exclusion Criteria:

Patients with a history of psychiatric disease
Diabetic or alcoholic patients who may have impaired sensation due peripheral neuropathies
chronic opioid or nonsteroidal antiinflammatory drug use
chronic pain conditions

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

主要用途：支持治疗
分配：不适用
介入模型：单组作业
屏蔽：无（打开标签）

手臂数量

武器和干预

参与者组/臂	干预/治疗
无干预：Patients undergoing hysterectomy	设备：Thermal Sensory Analyzer (Senselab) Thermal stimuli will be administered to the ventral surface of the dominant forearm and then to the lower abdomen (surgical site)using the Thermal Sensory Analyser. Each thermal testing trial will be separated by approximately 2 min and at a separate site. To measure the thermal pain threshold temperature, The thermode will be applied to the ventral surface of the dominant forearm and the temperature will be increased at 1°C/s from 35 to 50°C. To measure the Suprathreshold Thermal Pain Intensity and unpleasantness, Stimulus responses for noxious heat stimuli will be performed by applying phasic heat stimuli at 8 different temperatures (35, 43, 44, 45, 46, 47, 48, and 49°C). 其他名称： Modular Sensory Analyzer, Senselab

参与者组/臂

干预/治疗

无干预：Patients undergoing hysterectomy

设备：Thermal Sensory Analyzer (Senselab)

Thermal stimuli will be administered to the ventral surface of the dominant forearm and then to the lower abdomen (surgical site)using the Thermal Sensory Analyser. Each thermal testing trial will be separated by approximately 2 min and at a separate site.

To measure the thermal pain threshold temperature, The thermode will be applied to the ventral surface of the dominant forearm and the temperature will be increased at 1°C/s from 35 to 50°C.

To measure the Suprathreshold Thermal Pain Intensity and unpleasantness, Stimulus responses for noxious heat stimuli will be performed by applying phasic heat stimuli at 8 different temperatures (35, 43, 44, 45, 46, 47, 48, and 49°C).

其他名称：

Modular Sensory Analyzer, Senselab

研究衡量的是什么？

主要结果指标

结果测量	大体时间
pain scores from IV insertion 大体时间：15 minutes prior to induction	15 minutes prior to induction

次要结果测量

结果测量	措施说明	大体时间
Anxiety 大体时间：24 to 48 hours before surgery		24 to 48 hours before surgery
Pain from thermal stimuli 大体时间：24 to 48 hours before surgery	Pain from thermal stimuli will be measure at two sites: site of surgery and at the forearm.	24 to 48 hours before surgery
Suprathreshold Thermal pain intensity 大体时间：24 to 48 hours before surgery	Suprathreshold Thermal pain intensity will be recorded at two site: site of surgery and forearm	24 to 48 hours before surgery
suprathreshold thermal unpleasantness intensity 大体时间：24 to 48 hours before surgery		24 to 48 hours before surgery
Expectation about pain 大体时间：24 to 48 hours before surgery		24 to 48 hours before surgery
postoperative pain 大体时间：within 1-2 hours after arrival to recovery room; and at 12 hours, 24 hours, 36 hours and 48 hours after surgery	Postoperative pain will be measured upon arrival to the Post Anesthesia Care Unit (PACU)before morphine consumption and after morphine consumption, at rest and at movement.	within 1-2 hours after arrival to recovery room; and at 12 hours, 24 hours, 36 hours and 48 hours after surgery
Morphine consumption 大体时间：within 1-2 hours after arrival to recovery room; and at 12 hours, 24 hours, 36 hours and 48 hours after surgery		within 1-2 hours after arrival to recovery room; and at 12 hours, 24 hours, 36 hours and 48 hours after surgery

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

American University of Beirut Medical Center

调查人员

首席研究员：Marie T Aouad, MD、American University of Beirut Medical Center

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2012年7月1日

初级完成 (实际的)

2014年3月1日

研究完成 (实际的)

2014年3月1日

研究注册日期

首次提交

2011年9月28日

首先提交符合 QC 标准的

2011年10月7日

首次发布 (估计)

2011年10月10日

研究记录更新

最后更新发布 (估计)

2014年5月16日

上次提交的符合 QC 标准的更新

2014年5月15日

最后验证

2013年9月1日

Predictors of Postoperative Pain