In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome
In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome.
Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication.
The INVOS (In Vivo Optical Spectroscopy) monitors tissular oxygenation continuously and non-invasively.
The objective is to develop a model mimicking the physiopathology of MCS to assess the interest of the INVOS in this case.
研究概览
详细说明
研究类型
注册 (实际的)
阶段
- 阶段1
联系人和位置
学习地点
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Brussels、比利时、1200
- Cliniques Universitaires Saint-Luc
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Healthy volunteers
- >18yr
- Informed consent
- Male
Exclusion Criteria:
- Neuropathies
- Vascular pathology
- Actual pain
- Anti-platelet or anticoagulant therapy
- Ipsilateral history of fracture
学习计划
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Tourniquet
Inflation of a tourniquet
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Inflation of a tourniquet (pressure equal to the mean arterial pressure) obtaining a model of slight venous congestion and arterial hypoperfusion
Near Infraread spectroscopy, non invasive
Electromyography, non invasive
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Comparison Between INVOS Monitoring and Electromyography
大体时间：45 minutes
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A comparison will be made between the INVOS monitoring and non invasive (transcutaneous) EMG monitoring (AP Block), to determine the accuracy of the INVOS monitoring to predict AP block. Measures were: [mean (SD)] INVOS (in %) value at baseline and at the time of the block |
45 minutes
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Intracompartmental Pressure (ICP)
大体时间：45 minutes
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[mean (SD)] ICP (in mmHg), value at baseline and at the time of the block
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45 minutes
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合作者和调查者
调查人员
- 首席研究员：Patrice Forget, M.D.、UCL
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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