Analgesia in Children Using Caudal Epidural Ropivacaine
Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine: A Prospective, Randomized, Double-blinded, Controlled Study
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al 1994). Furthermore, studies have shown that children receiving caudal blocks have secondary benefits such as lower narcotic and anesthetic requirements, more rapid awakening from general anesthesia, decreased time to discharge home, and fewer pain-related behaviors postoperatively (Conroy et al 1993, Tobias et al 1995, Tobias 1996).
This proposed study involves the use of a caudal block in children undergoing elective inguinal herniorrhaphy or orchiopexy to evaluate the role of preemptive analgesia in pediatric pain management. We hypothesize that by inhibiting peripheral pain receptors with a caudal block before the onset of a painful stimulus, we can decrease central nervous system sensitization and reduce postoperative analgesic requirements
研究概览
研究类型
注册 (实际的)
联系人和位置
学习地点
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California
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Loma Linda、California、美国、92354
- Loma Linda University Medical Center
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Loma Linda、California、美国、92354
- Loma Linda University Outpatient Surgery Center
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Age 2 months to 2 years
- Weight 25kg or less
- ASA class 1, 2, 3
- Elective inguinal herniorrhaphy or orchiopexy
Exclusion Criteria:
- Contraindications to caudal epidural analgesia
- parent's refusal
- skeletal or spinal cord anomaly
- coagulopathy
- infection at the insertion site
- ongoing bacteremia
- allergy to ropivacaine
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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Group CB (Caudal Before-study group)
This group will receive caudal ropivacaine and epinephrine after induction of general anesthesia prior to surgical incision
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Caudal After (CA)-control group
This group will receive caudal ropivacaine with epinephrine after completion of surgery but before emergence from anesthesia
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Local Infiltration After (LIA) control group
This group will receive local infiltration of ropivacaine around the surgery site at the conclusion of surgery but before emergence from anesthesia
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
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Usage of pain medications
大体时间:over 24 hours
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over 24 hours
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次要结果测量
结果测量 |
大体时间 |
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Pain scores
大体时间:At various intervals for first 24 hours
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At various intervals for first 24 hours
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合作者和调查者
调查人员
- 首席研究员:Shannon Mulder, MD、Loma Linda University Medical Center
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- 5110235
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