Regional Distribution of Ventilation to Assess Respiratory Muscle Dysfunction (DREM)
Construction of a Database to Identify Early Indicators of Respiratory Muscle Dysfunction in Neuromuscular Patients From the Optoelectronic Plethysmography Assessment of the Thoracoabdominal Motion
研究概览
详细说明
All patients which had suspected respiratory muscle dysfunction will have usual exploration of the respiratory muscles according to the clinician prescription. These explorations can include :
- Lung volumes in seating and supine position
- Maximal inspiratory and expiratory pressures
- Maximal sniff pressures
And when diaphragmatic dysfunction is suspected :
- Maximal transdiaphragmatic pressure
- Phrenic nerve conduction
These patients will also beneficiate to the determination of volume variations of the upper rib cage, the lower rib cage and the abdominal compartments by using Opto-electronic plethysmography.
研究类型
注册 (预期的)
联系人和位置
学习地点
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-
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Garches、法国、92380
- Raymond Poincaré Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- suspicion of respiratory muscle dysfunction
- indication of diaphragm exploration
Exclusion Criteria:
- acute respiratory failure
学习计划
研究是如何设计的？
设计细节
- 观测模型：队列
- 时间观点：预期
队列和干预
团体/队列 |
|---|
|
respiratory muscle dysfunction patients
Neuromuscular patients
|
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diaphragmatic dysfunction
patients who present orthopnea, recruitment of accessory muscles, abdominal paradox, respiratory dysfunction or dyssynchronous movement
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
compartmental distribution of the inspired/expired volumes
大体时间：1 hour
|
Measurements of the thoraco-abdominal motion and of the global lung volume changes. Measurements will be done during spontaneous breathing and during vital capacity maneuvers. Therefore the tidal volume, the inspiratory capacity and the expiratory reserve volume will be measured in liters and for each compartiment (upper thorax, lower thorax, abdomen) contribution of these volumes will be expressed in percentage. |
1 hour
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
left side and right side contribution to the inspired/expired volumes
大体时间：1 hour
|
Measurements will be done during spontaneous breathing and during vital capacity maneuvers.
Therefore the tidal volume, the inspiratory capacity and the expiratory reserve volume will be measured in liters and each side contribution of these volumes will be expressed in percentage.
|
1 hour
|
合作者和调查者
调查人员
- 首席研究员：Frederic Lofaso, MD, PhD、Centre d'Investigation Clinique et Technologique 805
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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