Combined Dietary Education of Low Sodium and High Potassium Consumption
Research for the Effectiveness of Combined Dietary Education of Low Sodium and High Potassium Consumption
Reduction in sodium consumption is important approach in public health care. In general population, reduction of sodium intake can reduce the future development of hypertension and cardiovascular event. Meanwhile, enhancement of potassium consumption is also important to reduce blood pressure and cardiovascular events. We hypothesized that combined education of low sodium and high potassium consumption is more effective in reducing blood pressure compared to dietary education of low sodium consumption only.
The present survey study was designed to test the effectiveness of combined education of low sodium and high potassium consumption in blood pressure reduction and improvement of other variables.
研究概览
地位
研究类型
注册 (预期的)
阶段
- 不适用
联系人和位置
学习地点
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Gyeonggi
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Goyang、Gyeonggi、大韩民国、410-773
- 招聘中
- Dongguk University Ilsan Hospital
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接触：
- Moo-Yong Rhee, MD, PhD
- 电话号码：82 31 961 7125
- 邮箱：mooyong.rhee@gmail.com
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接触：
- Ji-Hyun Kim, MD, PhD
- 电话号码：82 31 961 7270
- 邮箱：mdangela79@gmail.com
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副研究员：
- Ji-Hyun Kim, MD, PhD
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首席研究员：
- Moo-Yong Rhee, MD, PhD
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Prehypertension: with a systolic pressure from 120 to 139 mm Hg or a diastolic pressure from 80 to 89 mm Hg
- Stage 1 hypertension: with a systolic pressure from 140 to 159 mm Hg or a diastolic pressure from 90 to 99 mm Hg
Exclusion Criteria:
- Urinary tract disease
- Secondary hypertension
- Previous history of unstable angina, heart failure, myocardial infarction, coronary revascularization, cerebrovascular disease within 12 months
- Ventricular tachycardia, atrial fibrillation and flutter
- Hypertrophic cardiomyopathy
- Known chronic kidney disease: serum creatinine = or > 2.0 mg/dL
- Hypokalemia (<3.5 mmol/L) or hyperkalemia (>5.5 mmol/L)
- Type 1 diabetes mellitus
- Poorly controlled diabetes mellitus (HbA1C = or > 9%)
- Unable to collect 24 hour urine sample
- Pregnancy
- Alcoholics
- Severe liver disease
- Night workers
- Mental retardation
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Group 1
dietary education of low sodium and high potassium consumption
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有源比较器：Group 2
dietary education of low sodium consumption only
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
changes of 24-hour ambulatory systolic and diastolic blood pressure
大体时间：3 months
|
Effectiveness of combined dietary education of low sodium and high potassium consumption on changes of 24-hour ambulatory systolic and diastolic blood pressure, compared to dietary education of low sodium consumption only.
|
3 months
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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changes of 24-hour urine sodium and potassium excretion
大体时间：3 months
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Difference of changes of 24-hour urine sodium and potassium excretion by each dietary education
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3 months
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changes of renin and aldosterone
大体时间：3 months
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Difference in changes of renin and aldosterone by each dietary education
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3 months
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其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Changes of renin and aldosterone
大体时间：3 months
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Changes of renin and aldosterone by low sodium consumption
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3 months
|
|
Changes of pulse wave velocity
大体时间：3 months
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Changes of pulse wave velocity by low sodium consumption
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3 months
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Changes of left ventricular mass index
大体时间：3 months
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Changes of left ventricular mass index by low sodium consumption
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3 months
|
合作者和调查者
调查人员
- 首席研究员：Moo-Yong Rhee, MD, PhD、Dongguk University
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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