Common Canister Protocol for Inhaler Administration in Mechanically Ventilated Patients
Common Canister Protocol for Metered Dose Inhaler Administration in Mechanically Ventilated Patients
Many hospitals employ a common canister inhaler protocol in patients that do not require mechanical ventilator support. Common canister refers to a single inhaler paired with standardized cleaning methods for use on more than one patient. Small reports suggest that this method does not pose an increased infectious risk and is associated with significant cost savings.
Common canister protocols offer a solution to the discordance between inhaler sizes and average inpatient use of the drugs. Metered dose inhaler canisters are contain enough drug for several days to weeks of daily use. However, the average length of stay for most inpatients is only several days. Therefore, most inpatients do not use all of the canister contents, an unused resource that is potentially wasted.
The common canister approach has not been previously described in mechanically ventilated patients (people requiring intensive care unit admission on breathing machines). This study aims to assess the safety of common canister utilization by assessment and comparison of infection rates in the study and control group.
研究概览
研究类型
注册 (实际的)
阶段
- 第四阶段
联系人和位置
学习地点
-
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Missouri
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Saint Louis、Missouri、美国、63110
- Barnes-Jewish Hospital
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- mechanically ventilated patients prescribed bronchodilator therapy in a medical intensive care unit
Exclusion Criteria:
- lung transplant
- neutropenic
- contact isolation
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:非随机化
- 介入模型:并行分配
- 屏蔽:无(打开标签)
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的:Common canister
Use of a single MDI (instead of assigning each patient an individual MDI) for multiple mechanically ventilated patients.
Inhalers will undergo a stringent cleaning protocol between administrations and storage.
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Drug administration via a shared canister with a standardized cleaning protocol.
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|
无干预:Control
Each patient will be assigned an individual inhaler as per standard of care practice.
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Ventilator-associated pneumonia (VAP)
大体时间:48 hours after intubation
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Pneumonia that developed in association with mechanical ventilation
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48 hours after intubation
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Inhaler drug cost
大体时间:During period of mechanical ventilation, which varies depending on patient's severity of illness and reason for intubation; on average may range from 3-5 days.
|
Inhaler charges accrued during mechanical ventilation
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During period of mechanical ventilation, which varies depending on patient's severity of illness and reason for intubation; on average may range from 3-5 days.
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合作者和调查者
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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