Follow-up of Sollentuna Prevention Program (SoPP)
Long-term Follow-up of an Individual and Population-based Program Aimed at Preventing Cardiovascular Disease in Sollentuna Municipality
研究概览
地位
条件
详细说明
In Sweden there are unique opportunities to create a relevant comparison group for this study, which is of great importance to the value of this cohort study.
Of the three study populations two (2-3)will be created by using national registries.
- The screened group consists of the individuals (n = 5938) who had direct contact with the prevention program, ie undergone a voluntary opportunistic cardiovascular screening (questionnaire, physical examination and testing in connection with visits to health centers) and the rest of all individuals who lived in Sollentuna Municipality between 1988-1993.
- Relatives of individuals included in the screened group who lived in Stockholm county at the time of the intervention will be identified by the use of the Medical Birth Register and the Multi-Generation Register. Family members are defined as parents, siblings and children and husband / wife to those in thescreened group and will be analyzed in the same way as those who participated in the intervention for risk of developing cardiovascular disease and cancer.
- The comparison group consists of the entire population of Stockholm County minus Sollentuna 1988-93, taking into account population changes (migration, birth, death) during the period.
This three populations will be followed-up in national registries and databases
All subjects will be monitored for example disease history, socio-economics and biochemical risk factors presented below national registries and research databases. When all the matches of national registers and a local register (AMORIS)have been done the database will de-identified and anonymized data to be available for statistical processing.
研究类型
注册 (预期的)
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
The screened group who participated in the cardiovascular prevention program:
(n=5938) and the rest of the population in Sollentuna Municipality.
- To the screened group matched "controls" will be selected randomly from the population of Stockholm County minus Sollentuna. The population in Sollentuna will compared to the population of Stockholm County minus Sollentuna Municipality.
- Relatives of individuals included in the intervention group and who lived in Stockholm County at the time of the intervention will be identified by use of national registers.
描述
Inclusion Criteria in the risk intervention group:
- Individuals 15 years of age or more who visited three (four) health care centres in Sollentuna 1988-1993 were offered to participate in the prevention program
Exclusion Criteria in the screened intervention group:
- Age < 15 years
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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Screened group
Screened group is defined as those individuals who were willing to participate in the cardiovascular prevention program and all the individuals who lived in Sollentuna during the intervention.
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Relatives to the screened group
Relatives to individuals included in the screened group, who lived in Stockholm County at least during one year at the time of the intervention.
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Control group
Matched "controls" is going to be selected randomly from the population of Stockholm County minus Sollentuna Municipality with relevant background factors.
The whole population will be used as a comparison group when evaluating the result from all the municipality of Sollentuna during 1988-1993.
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Incidence and mortality in acute myocardial infarction, stroke, cardiovascular disease, and overall mortality, a twenty year follow-up of a prevention program.
大体时间:24 years
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Long term follow-up of a cardiovascular prevention program by using Swedish national patient registries
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24 years
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
A follow-up of drug treatment of diabetes, dyslipidemia and hypertension
大体时间:24 years
|
By using the drug register in Sweden do a follow-up of drug treatment in the cohort
|
24 years
|
其他结果措施
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Incidence and mortality in cancer
大体时间:24 years
|
Incidence and mortality in cancer - a twenty year follow-up by using the swedish cancer register
|
24 years
|
Consumption of medical care overall and for different diagnostic groups
大体时间:24 years
|
To study medical care consumption overall for different diagnostic groups by using different registers in Sweden
|
24 years
|
Health economic aspects
大体时间:24 years
|
Health economic aspects such as
|
24 years
|
Time trends of morbidity and mortality in acute myocardial infarction, stroke, cardiovascular disease and total mortality
大体时间:24 years
|
To study time trends of morbidity and mortality in acute myocardial infarction, stroke, cardiovascular disease and total mortality by use of National Swedish registries.
|
24 years
|
合作者和调查者
调查人员
- 首席研究员:Gunilla Journath, PhD、Karolinska Institutet
出版物和有用的链接
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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