EFFects of Thrombophilia on the Outcomes of Assisted Reproduction Technologies
EFFects of Thrombophilia on the Outcomes of Assisted Reproduction
Both hereditary and acquired thrombophilia have been associated with recurrent miscarriage and pregnancy complications. Thrombophilia could favor the development of thrombosis of the maternal vasculature and obstacle placentation. Some studies have suggested a role of thrombophilia in the failure of assisted reproductive techniques although this association has been recently questioned. The scope of this study is to evaluate the effect of thrombophilia on the implantation rate and live birth rate in women undergoing ART.
Design: prospective, observational study Primary end-point: live birth rate. Secondary end-points: implantation rate, venous thromboembolic events during ART up to 6 weeks post-partum
研究概览
地位
条件
研究类型
注册 (实际的)
联系人和位置
学习地点
-
-
-
Chieti、意大利、66100
- Universita degli Studi G. d'Annunzio Chieti e Pescara
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- women undergoing ART
- age 18 years or older
Exclusion Criteria:
- ongoing anticoagulant therapy
- previous venous thromboembolism
- no informed consent
学习计划
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
Live birth rate
大体时间：Participants will be followed for the duration of the pregnancy, an expected average of 9 months
|
Participants will be followed for the duration of the pregnancy, an expected average of 9 months
|
次要结果测量
结果测量 |
大体时间 |
|---|---|
|
implantation rate
大体时间：Participants will be followed from the implantation to the ultrasonography to document the gestational sac, an expected average of 7 weeks
|
Participants will be followed from the implantation to the ultrasonography to document the gestational sac, an expected average of 7 weeks
|
合作者和调查者
调查人员
- 首席研究员：Marcello Di Nisio、University G. D'Annunzio, Chieti, Italy
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.