The Correlation Between Testosterone and Cortisol Level and Inflammatory Markers Levels in Type 2 Diabetic Men. (BZMC)
Many type 2 diabetic men have low serum testosterone levels. Our aim in this trial is to check if there is a correlation between serum or hair testosteron levels and serum or hair cortisol levels in type 2 diabetic men. We'll also examine whether there is a correlation between serum and hair testosterone levels and cortisol levels and serum inflammatory markers.
If such correlation will be found- then it is possible that excess cortisol or an abnormal inflammatory status- may cause the low testosterone levels that seen in type 2 diabetic men.
研究概览
地位
条件
详细说明
Eligible participants are type 2 diabetic men who visit our clinic, as part of their routine medical surveillance, and other 10 healthy volunteers (men) as a control group.
All the participants will sign an informed consent form. The study will include 30 type 2 diabetic men, (40-55 years old) and 10 healthily volunteers (same age group).
In addition to routine blood test of blood count, kidney function and liver enzymes will be taken blood samples of total testosterone serum levels, total cortisol serum levels and serum inflammation markers levels, and also a sample of head-hair for cortisol and testosterone levels (1 cm of occipital hair weighing 50 mg).
Optional: from patients who will agree to visit the clinic after 8 hours-fast will be also taken one additional blood sample of fasting glucose, insulin and C-peptide levels, in order to estimate their insulin resistance status, and it's possible correlation to the other measures.
From the 10 healthy volunteers In addition will be taken blood and hair samples of the above parameters, as a control.
研究类型
注册 (预期的)
联系人和位置
学习地点
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Haifa、以色列
- 招聘中
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接触：
- Julia Sterlin
- 电话号码：97248359281
- 邮箱：julia.sterlin@gmail.com
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- men age 40-55
- type 2 diabetic
Exclusion Criteria:
- HIV
- septic disease
学习计划
研究是如何设计的？
设计细节
- 观测模型：其他
- 时间观点：预期
队列和干预
团体/队列 |
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two parallel group
group with inflammatory markers high levels and control group with inflammatory normal levels markers.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Testosterone level
大体时间：24 months
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single blood and hair sample will be drawn to measure Testosterone levels (nmol/L)
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24 months
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Cortisol level
大体时间：24 months
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single blood and hair sample will be drawn to measure cortisol levels (mcg/dl)
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24 months
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C-reactive protein levels
大体时间：24 months
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single blood sample will be drawn to measure c-reactive protein levels (mcg/dl)
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24 months
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Anti Tumor Necrosis Factor alpha
大体时间：24 months
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single blood sample will be drawn to measure Anti Tumor Necrosis Factor alpha levels (pg/ml)
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24 months
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
其他研究编号
- 0045-15BNZ
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
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